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fusA fusA rpl37ae rpl37ae rpl12p rpl12p rpl1 rpl1 rps15 rps15 rps3ae rps3ae rpl44e rpl44e rps24e rps24e rpl10e rpl10e rpl15e rpl15e rpl18a rpl18a rpl21e rpl21e rpl14e rpl14e rpl34e rpl34e rps17e rps17e rpl40e rpl40e rpl24e rpl24e rps28e rps28e rps7 rps7 rps12 rps12 rpl30e rpl30e eif1a eif1a rpl13 rpl13 rpl18e rpl18e rps13 rps13 rpl30p rpl30p rpl18 rpl18 rpl19e rpl19e rpl32e rpl32e rpl6 rpl6 rps8 rps8 rps14P rps14P rpl5 rpl5 rps4e rps4e rpl24p rpl24p rpl14 rpl14 rps17 rps17 rpl29 rpl29 rps3 rps3 rpl22 rpl22 rpl2p rpl2p rpl23 rpl23 rpl3 rpl3 rpl35ae rpl35ae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fusATranslation elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (732 aa)
rpl37aeLSU ribosomal protein L37Ae; Binds to the 23S rRNA. (83 aa)
rpl12pLSU ribosomal protein L12a (P1/P2); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (107 aa)
rpl1LSU ribosomal protein L10Ae (L1p); Binds directly to 23S rRNA. Probably involved in E site tRNA release. (216 aa)
rps15SSU ribosomal protein S13e (S15p). (159 aa)
rps3aeSSU ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (199 aa)
rpl44eLSU ribosomal protein L44e; Binds to the 23S rRNA. (94 aa)
rps24eSSU ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (99 aa)
rpl10eLSU ribosomal protein L10e (L16p); Belongs to the universal ribosomal protein uL16 family. (181 aa)
rpl15eLSU ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (194 aa)
rpl18aLSU ribosomal protein L18Ae. (77 aa)
rpl21eLSU ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa)
rpl14eLSU ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family. (83 aa)
rpl34eLSU ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family. (87 aa)
rps17eSSU ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (67 aa)
rpl40e50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (51 aa)
rpl24eLSU ribosomal protein L24e; Binds to the 23S rRNA. (67 aa)
rps28eSSU ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (71 aa)
rps7SSU ribosomal protein S5e (S7p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (215 aa)
rps12SSU ribosomal protein S23e (S12p); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa)
rpl30eLSU ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family. (99 aa)
eif1aTranslation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (113 aa)
rpl1350S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa)
rpl18eLSU ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family. (120 aa)
rps13SSU ribosomal protein S18e (S13p); Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (148 aa)
rpl30pLSU ribosomal protein L7e (L30p). (155 aa)
rpl18LSU ribosomal protein L5e (L18p); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (203 aa)
rpl19eLSU ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (150 aa)
rpl32eLSU ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family. (130 aa)
rpl6LSU ribosomal protein L9e (L6p); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (184 aa)
rps8SSU ribosomal protein S15Ae (S8p); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rps14PSSU ribosomal protein S29e (S14p); Binds 16S rRNA, required for the assembly of 30S particles. (56 aa)
rpl5LSU ribosomal protein L11e (L5p); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (186 aa)
rps4eSSU ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. (243 aa)
rpl24pLSU ribosomal protein L26e (L24p); Located at the polypeptide exit tunnel on the outside of the subunit. (121 aa)
rpl14LSU ribosomal protein L23e (L14p); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (141 aa)
rps17SSU ribosomal protein S11e (S17p); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (112 aa)
rpl29LSU ribosomal protein L35e (L29p); Belongs to the universal ribosomal protein uL29 family. (68 aa)
rps3SSU ribosomal protein S3e (S3p); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (210 aa)
rpl22LSU ribosomal protein L17e (L22p); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (155 aa)
rpl2pLSU ribosomal protein L8e (L2p); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (239 aa)
rpl23LSU ribosomal protein L23Ae (L23p); Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (86 aa)
rpl3LSU ribosomal protein L3e (L3p); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (359 aa)
rpl35aeLSU ribosomal protein L35Ae; Belongs to the eukaryotic ribosomal protein eL33 family. (87 aa)
Your Current Organism:
Thermococcus chitonophagus
NCBI taxonomy Id: 54262
Other names: DSM 10152, T. chitonophagus, strain GC74
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