(10 nodes) Lysine biosynthetic process via aminoadipic acid network (Thermococcus chitonophagus)

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Your Input:
	CUX77458.1	(R)-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (534 aa)
	lysZ	Acetylaminoadipate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (249 aa)
	lysJ	N-acetyl-lysine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (369 aa)
	lysK	N-acetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. Belongs to the peptidase M20A family. LysK subfamily. (326 aa)
	argC	N-acetyl-gamma-aminoadipyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (330 aa)
	CUX78763.1	Homocitrate synthase. (359 aa)
	CUX78759.1	Lysine biosynthesis protein LysW. (55 aa)
	leuA	2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). (498 aa)
	CUX77546.1	Acetylornithine deacetylase. (411 aa)
	CUX78225.1	N-succinyl-L,L-diaminopimelate desuccinylase. (353 aa)

Your Current Organism:

Thermococcus chitonophagus

NCBI taxonomy Id: 54262
Other names: DSM 10152, T. chitonophagus, strain GC74

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUX77458.1	CUX78763.1	CHITON_0679	CHITON_1984	(R)-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	Homocitrate synthase.	0.910
CUX77458.1	leuA	CHITON_0679	CHITON_0683	(R)-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate).	0.977
CUX77546.1	argC	CHITON_0767	CHITON_1978	Acetylornithine deacetylase.	N-acetyl-gamma-aminoadipyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.	0.481
CUX78225.1	argC	CHITON_1446	CHITON_1978	N-succinyl-L,L-diaminopimelate desuccinylase.	N-acetyl-gamma-aminoadipyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.	0.569
CUX78225.1	lysJ	CHITON_1446	CHITON_1976	N-succinyl-L,L-diaminopimelate desuccinylase.	N-acetyl-lysine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.	0.609
CUX78225.1	lysK	CHITON_1446	CHITON_1975	N-succinyl-L,L-diaminopimelate desuccinylase.	N-acetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. Belongs to the peptidase M20A family. LysK subfamily.	0.925
CUX78759.1	CUX78763.1	CHITON_1980	CHITON_1984	Lysine biosynthesis protein LysW.	Homocitrate synthase.	0.531
CUX78759.1	argC	CHITON_1980	CHITON_1978	Lysine biosynthesis protein LysW.	N-acetyl-gamma-aminoadipyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.	0.843
CUX78759.1	lysJ	CHITON_1980	CHITON_1976	Lysine biosynthesis protein LysW.	N-acetyl-lysine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.	0.735
CUX78759.1	lysK	CHITON_1980	CHITON_1975	Lysine biosynthesis protein LysW.	N-acetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. Belongs to the peptidase M20A family. LysK subfamily.	0.892
CUX78759.1	lysZ	CHITON_1980	CHITON_1977	Lysine biosynthesis protein LysW.	Acetylaminoadipate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	0.872
CUX78763.1	CUX77458.1	CHITON_1984	CHITON_0679	Homocitrate synthase.	(R)-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.910
CUX78763.1	CUX78759.1	CHITON_1984	CHITON_1980	Homocitrate synthase.	Lysine biosynthesis protein LysW.	0.531
CUX78763.1	argC	CHITON_1984	CHITON_1978	Homocitrate synthase.	N-acetyl-gamma-aminoadipyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.	0.608
CUX78763.1	leuA	CHITON_1984	CHITON_0683	Homocitrate synthase.	2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate).	0.911
CUX78763.1	lysJ	CHITON_1984	CHITON_1976	Homocitrate synthase.	N-acetyl-lysine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.	0.538
CUX78763.1	lysK	CHITON_1984	CHITON_1975	Homocitrate synthase.	N-acetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. Belongs to the peptidase M20A family. LysK subfamily.	0.506
CUX78763.1	lysZ	CHITON_1984	CHITON_1977	Homocitrate synthase.	Acetylaminoadipate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.	0.540
argC	CUX77546.1	CHITON_1978	CHITON_0767	N-acetyl-gamma-aminoadipyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.	Acetylornithine deacetylase.	0.481
argC	CUX78225.1	CHITON_1978	CHITON_1446	N-acetyl-gamma-aminoadipyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.	N-succinyl-L,L-diaminopimelate desuccinylase.	0.569