(7 nodes) Thiamine pyrophosphate enzyme, TPP-binding network (Thermococcus chitonophagus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CUX77464.1	Acetolactate synthase large subunit. (562 aa)
	CUX78017.1	Indolepyruvate oxidoreductase subunit IorA; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (646 aa)
	CUX78670.1	2-oxoglutarate oxidoreductase, beta subunit. (281 aa)
	CUX78673.1	2-oxoglutarate oxidoreductase, beta subunit. (282 aa)
	CUX77450.1	Pyruvate:ferredoxin oxidoreductase, beta subunit. (331 aa)
	CUX77447.1	Ketoisovalerate oxidoreductase subunit VorB. (311 aa)
	CHITON_0996	Indolepyruvate oxidoreductase subunit IorA; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. (615 aa)

Your Current Organism:

Thermococcus chitonophagus

NCBI taxonomy Id: 54262
Other names: DSM 10152, T. chitonophagus, strain GC74

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUX77447.1	CUX77450.1	CHITON_0668	CHITON_0671	Ketoisovalerate oxidoreductase subunit VorB.	Pyruvate:ferredoxin oxidoreductase, beta subunit.	0.702
CUX77450.1	CUX77447.1	CHITON_0671	CHITON_0668	Pyruvate:ferredoxin oxidoreductase, beta subunit.	Ketoisovalerate oxidoreductase subunit VorB.	0.702
CUX77450.1	CUX77464.1	CHITON_0671	CHITON_0685	Pyruvate:ferredoxin oxidoreductase, beta subunit.	Acetolactate synthase large subunit.	0.916
CUX77450.1	CUX78670.1	CHITON_0671	CHITON_1891	Pyruvate:ferredoxin oxidoreductase, beta subunit.	2-oxoglutarate oxidoreductase, beta subunit.	0.900
CUX77450.1	CUX78673.1	CHITON_0671	CHITON_1894	Pyruvate:ferredoxin oxidoreductase, beta subunit.	2-oxoglutarate oxidoreductase, beta subunit.	0.900
CUX77464.1	CUX77450.1	CHITON_0685	CHITON_0671	Acetolactate synthase large subunit.	Pyruvate:ferredoxin oxidoreductase, beta subunit.	0.916
CUX77464.1	CUX78670.1	CHITON_0685	CHITON_1891	Acetolactate synthase large subunit.	2-oxoglutarate oxidoreductase, beta subunit.	0.916
CUX77464.1	CUX78673.1	CHITON_0685	CHITON_1894	Acetolactate synthase large subunit.	2-oxoglutarate oxidoreductase, beta subunit.	0.916
CUX78670.1	CUX77450.1	CHITON_1891	CHITON_0671	2-oxoglutarate oxidoreductase, beta subunit.	Pyruvate:ferredoxin oxidoreductase, beta subunit.	0.900
CUX78670.1	CUX77464.1	CHITON_1891	CHITON_0685	2-oxoglutarate oxidoreductase, beta subunit.	Acetolactate synthase large subunit.	0.916
CUX78670.1	CUX78673.1	CHITON_1891	CHITON_1894	2-oxoglutarate oxidoreductase, beta subunit.	2-oxoglutarate oxidoreductase, beta subunit.	0.979
CUX78673.1	CUX77450.1	CHITON_1894	CHITON_0671	2-oxoglutarate oxidoreductase, beta subunit.	Pyruvate:ferredoxin oxidoreductase, beta subunit.	0.900
CUX78673.1	CUX77464.1	CHITON_1894	CHITON_0685	2-oxoglutarate oxidoreductase, beta subunit.	Acetolactate synthase large subunit.	0.916
CUX78673.1	CUX78670.1	CHITON_1894	CHITON_1891	2-oxoglutarate oxidoreductase, beta subunit.	2-oxoglutarate oxidoreductase, beta subunit.	0.979