STRINGSTRING
CUX76794.1 CUX76794.1 tpiA tpiA CUX76804.1 CUX76804.1 ppcA ppcA CUX76887.1 CUX76887.1 apgM apgM CUX77007.1 CUX77007.1 CUX77016.1 CUX77016.1 CUX77027.1 CUX77027.1 CUX77031.1 CUX77031.1 CUX77033.1 CUX77033.1 CUX77105.1 CUX77105.1 pgiA pgiA pckG pckG eno eno CUX77229.1 CUX77229.1 prs prs CUX77278.1 CUX77278.1 CUX77287.1 CUX77287.1 CUX77288.1 CUX77288.1 CUX77289.1 CUX77289.1 CUX77351.1 CUX77351.1 rbcL rbcL CUX77401.1 CUX77401.1 CUX77442.1 CUX77442.1 CUX77444.1 CUX77444.1 porD porD porA-2 porA-2 CUX77450.1 CUX77450.1 CUX77489.1 CUX77489.1 CUX77528.1 CUX77528.1 CUX77535.1 CUX77535.1 CUX77546.1 CUX77546.1 CUX77573.1 CUX77573.1 CUX77580.1 CUX77580.1 CUX77606.1 CUX77606.1 CUX77607.1 CUX77607.1 pgk pgk CHITON_0909 CHITON_0909 CUX77689.1 CUX77689.1 thrB thrB CUX77691.1 CUX77691.1 CUX77692.1 CUX77692.1 CUX77745.1 CUX77745.1 ubiX ubiX CUX77776.1 CUX77776.1 CUX77869.1 CUX77869.1 CUX77870.1 CUX77870.1 CUX77871.1 CUX77871.1 CUX77874.1 CUX77874.1 CUX77996.1 CUX77996.1 CUX78016.1 CUX78016.1 fbp fbp CUX78069.1 CUX78069.1 CUX78070.1 CUX78070.1 CUX78097.1 CUX78097.1 glkA glkA gyaR gyaR CUX78159.1 CUX78159.1 CUX78173.1 CUX78173.1 CUX78223.1 CUX78223.1 CUX78238.1 CUX78238.1 CUX78276.1 CUX78276.1 rpiA rpiA CUX78338.1 CUX78338.1 CUX78385.1 CUX78385.1 CUX78435.1 CUX78435.1 CUX78449.1 CUX78449.1 CUX78461.1 CUX78461.1 CUX78494.1 CUX78494.1 CUX78525.1 CUX78525.1 CUX78547.1 CUX78547.1 CUX78553.1 CUX78553.1 CUX78608.1 CUX78608.1 CUX78641.1 CUX78641.1 CUX78643.1 CUX78643.1 pfkC pfkC glyA glyA CUX78669.1 CUX78669.1 CUX78670.1 CUX78670.1 CUX78671.1 CUX78671.1 CUX78672.1 CUX78672.1 CUX78673.1 CUX78673.1 CUX78674.1 CUX78674.1 CUX78675.1 CUX78675.1 CUX78696.1 CUX78696.1 CUX78697.1 CUX78697.1 gltX gltX CUX78751.1 CUX78751.1 CUX78752.1 CUX78752.1 CUX78760.1 CUX78760.1 CUX78804.1 CUX78804.1 CUX78855.1 CUX78855.1 CUX78874.1 CUX78874.1 gap gap
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CUX76794.1Glutamate synthase [NADPH] small chain. (476 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (229 aa)
CUX76804.1Phosphoserine phosphatase. (206 aa)
ppcAPhosphoenolpyruvate carboxylase, archaeal; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (469 aa)
CUX76887.1Tungsten-containing ferredoxin oxidoreductase WOR4. (616 aa)
apgM2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal type; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (410 aa)
CUX77007.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (817 aa)
CUX77016.1Fructose bisphosphate aldolase. (281 aa)
CUX77027.1PUA-PAPS reductase like fusion. (633 aa)
CUX77031.1Methylmalonyl-CoA epimerase. (133 aa)
CUX77033.1B12 binding domain of Methylmalonyl-CoA mutase. (143 aa)
CUX77105.1Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases. (187 aa)
pgiAGlucose-6-phosphate isomerase, archaeal; Belongs to the archaeal-type GPI family. (189 aa)
pckGPhosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (624 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
CUX77229.1Archaeal succinyl-CoA ligase [ADP-forming] alpha chain. (468 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (278 aa)
CUX77278.1Acylphosphate phosphohydrolase, putative. (91 aa)
CUX77287.1Citrate synthase (si). (371 aa)
CUX77288.1Isocitrate dehydrogenase [NADP]. (399 aa)
CUX77289.1Aconitate hydratase. (827 aa)
CUX77351.1D-glycerate 2-kinase. (431 aa)
rbcLRibulose-1,5-bisphosphate carboxylase, Type III; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (420 aa)
CUX77401.1Pyruvate kinase; Belongs to the pyruvate kinase family. (476 aa)
CUX77442.1Nonspecific lipid-transfer protein (acethyl CoA synthetase). (388 aa)
CUX77444.1Pyruvate:ferredoxin oxidoreductase, gamma subunit / Ketoisovalerate oxidoreductase subunit VorG. (185 aa)
porDPyruvate:ferredoxin oxidoreductase, delta subunit. (105 aa)
porA-2Pyruvate:ferredoxin oxidoreductase, alpha subunit. (395 aa)
CUX77450.1Pyruvate:ferredoxin oxidoreductase, beta subunit. (331 aa)
CUX77489.1COG1720: Uncharacterized conserved protein / Uncharacterized protein MA0381. (230 aa)
CUX77528.1Acetamidase/formamidase. (291 aa)
CUX77535.1Homoserine dehydrogenase. (320 aa)
CUX77546.1Acetylornithine deacetylase. (411 aa)
CUX77573.1Glutamate synthase [NADPH] small chain. (475 aa)
CUX77580.1Hypothetical protein. (267 aa)
CUX77606.1Formate dehydrogenase-O, major subunit. (682 aa)
CUX77607.1Fe-S-cluster-containing hydrogenase components 1. (164 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (409 aa)
CHITON_0909Aspartate-semialdehyde dehydrogenase. (334 aa)
CUX77689.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (394 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (292 aa)
CUX77691.1Aspartokinase; Belongs to the aspartokinase family. (356 aa)
CUX77692.1Aspartokinase. (376 aa)
CUX77745.1Phosphomannomutase. (455 aa)
ubiXUbiX family decarboxylase associated with menaquinone via futalosine; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (187 aa)
CUX77776.1Tungsten-containing aldehyde:ferredoxin oxidoreductase. (607 aa)
CUX77869.1Methylmalonyl-CoA decarboxylase, gamma chain. (124 aa)
CUX77870.1Biotin carboxyl carrier protein of methylmalonyl-CoA decarboxylase. (146 aa)
CUX77871.1Methylmalonyl-CoA decarboxylase, beta chain. (400 aa)
CUX77874.1Carbamate kinase; Belongs to the carbamate kinase family. (314 aa)
CUX77996.1Putative glutamate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa)
CUX78016.1Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (457 aa)
fbpFructose-1,6-bisphosphatase, type V, archaeal; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (375 aa)
CUX78069.1Putative FMN hydrolase; 5-Amino-6-(5'-phosphoribitylamino)uracil phosphatase. (233 aa)
CUX78070.1Glyceraldehyde-3-phosphate: ferredoxin oxidoreductase. (653 aa)
CUX78097.1Glutamine synthetase type I. (439 aa)
glkAADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. (455 aa)
gyaRGlyoxylate reductase / Hydroxypyruvate reductase. (334 aa)
CUX78159.1Hypothetical NagD-like phosphatase. (280 aa)
CUX78173.1D-isomer specific 2-hydroxyacid dehydrogenase family protein. (334 aa)
CUX78223.1Pyruvate carboxyl transferase subunit B. (469 aa)
CUX78238.1Arylmalonate decarboxylase. (236 aa)
CUX78276.1Tungsten-containing formaldehyde:ferredoxin oxidoreductase. (619 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (229 aa)
CUX78338.1Formate dehydrogenase H. (659 aa)
CUX78385.1Methylmalonyl-CoA mutase. (562 aa)
CUX78435.14-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (454 aa)
CUX78449.1Threonine synthase. (441 aa)
CUX78461.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (304 aa)
CUX78494.1Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (443 aa)
CUX78525.1Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (462 aa)
CUX78547.1Leucyl aminopeptidase. (350 aa)
CUX78553.1Hydantoin racemase. (218 aa)
CUX78608.1NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (420 aa)
CUX78641.1Threonine synthase. (341 aa)
CUX78643.1Enolase. (341 aa)
pfkCADP-dependent phosphofructokinase; Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor. (454 aa)
glyASerine hydroxymethyltransferase / H4MPt-dependent SHMT; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (427 aa)
CUX78669.12-oxoglutarate oxidoreductase, gamma subunit. (181 aa)
CUX78670.12-oxoglutarate oxidoreductase, beta subunit. (281 aa)
CUX78671.12-oxoglutarate oxidoreductase, alpha subunit. (385 aa)
CUX78672.12-oxoglutarate oxidoreductase, gamma subunit. (170 aa)
CUX78673.12-oxoglutarate oxidoreductase, beta subunit. (282 aa)
CUX78674.12-oxoglutarate oxidoreductase, alpha subunit. (396 aa)
CUX78675.12-oxoglutarate oxidoreductase, delta subunit, putative. (89 aa)
CUX78696.1Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase alpha subunit. (273 aa)
CUX78697.1Fumarate hydratase class I, aerobic; L(+)-tartrate dehydratase beta subunit. (164 aa)
gltXGlutamyl-tRNA synthetase @ Glutamyl-tRNA(Gln) synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (572 aa)
CUX78751.1Transketolase, C-terminal section. (306 aa)
CUX78752.1Transketolase, N-terminal section. (217 aa)
CUX78760.1Homoisocitrate dehydrogenase. (345 aa)
CUX78804.1Acetyl-CoA synthetase (ADP-forming) alpha and beta chains, putative. (232 aa)
CUX78855.1Archaeal succinyl-CoA ligase [ADP-forming] beta chain. (252 aa)
CUX78874.1Glutamate synthase [NADPH] small chain. (348 aa)
gapNAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase archaeal. (334 aa)
Your Current Organism:
Thermococcus chitonophagus
NCBI taxonomy Id: 54262
Other names: DSM 10152, T. chitonophagus, strain GC74
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