node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS16973.1 | panD | Vapar_0310 | Vapar_2075 | PFAM: Aldehyde Dehydrogenase; KEGG: rfr:Rfer_0880 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.905 |
ACS16973.1 | panD-2 | Vapar_0310 | Vapar_6002 | PFAM: Aldehyde Dehydrogenase; KEGG: rfr:Rfer_0880 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.905 |
ACS17694.1 | ACS18382.1 | Vapar_1043 | Vapar_1732 | PFAM: Aldehyde Dehydrogenase; KEGG: aav:Aave_2256 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | PFAM: Aldehyde Dehydrogenase; KEGG: pna:Pnap_1598 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.902 |
ACS18382.1 | ACS17694.1 | Vapar_1732 | Vapar_1043 | PFAM: Aldehyde Dehydrogenase; KEGG: pna:Pnap_1598 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | PFAM: Aldehyde Dehydrogenase; KEGG: aav:Aave_2256 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.902 |
ACS18971.1 | panD | Vapar_2344 | Vapar_2075 | PFAM: Aldehyde Dehydrogenase; KEGG: pol:Bpro_2290 aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.905 |
ACS18971.1 | panD-2 | Vapar_2344 | Vapar_6002 | PFAM: Aldehyde Dehydrogenase; KEGG: pol:Bpro_2290 aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.905 |
ACS22548.1 | panD | Vapar_5977 | Vapar_2075 | PFAM: Aldehyde Dehydrogenase; KEGG: reu:Reut_A1842 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.905 |
ACS22548.1 | panD-2 | Vapar_5977 | Vapar_6002 | PFAM: Aldehyde Dehydrogenase; KEGG: reu:Reut_A1842 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.905 |
ACS22834.1 | panD | Vapar_6271 | Vapar_2075 | PFAM: Aldehyde Dehydrogenase; KEGG: pfo:Pfl01_2261 aldehyde dehydrogenase. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.905 |
ACS22834.1 | panD-2 | Vapar_6271 | Vapar_6002 | PFAM: Aldehyde Dehydrogenase; KEGG: pfo:Pfl01_2261 aldehyde dehydrogenase. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.905 |
clpP | clpX | Vapar_2511 | Vapar_2512 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.995 |
clpP | dnaJ | Vapar_2511 | Vapar_1711 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.532 |
clpP | dnaK | Vapar_2511 | Vapar_1712 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.724 |
clpP | groS | Vapar_2511 | Vapar_1119 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.875 |
clpP | panD | Vapar_2511 | Vapar_2075 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.435 |
clpP | panD-2 | Vapar_2511 | Vapar_6002 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.435 |
clpX | clpP | Vapar_2512 | Vapar_2511 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.995 |
clpX | dnaJ | Vapar_2512 | Vapar_1711 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.438 |
clpX | groS | Vapar_2512 | Vapar_1119 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.667 |
clpX | htpG | Vapar_2512 | Vapar_4976 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.480 |