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HCEG_00656 HCEG_00656 hxB hxB HCEG_00037 HCEG_00037 HCEG_00909 HCEG_00909 HCEG_00926 HCEG_00926 HCEG_01778 HCEG_01778 HCEG_00956 HCEG_00956 HCEG_01809 HCEG_01809 HCEG_01127 HCEG_01127 HCEG_00380 HCEG_00380 HCEG_01235 HCEG_01235 HCEG_01287 HCEG_01287 HCEG_01320 HCEG_01320 HCEG_02871 HCEG_02871 HCEG_02872 HCEG_02872 HCEG_03074 HCEG_03074 HCEG_03094 HCEG_03094 HCEG_02324 HCEG_02324 HCEG_02464 HCEG_02464 HCEG_02465 HCEG_02465 HCEG_02538 HCEG_02538 HCEG_01894 HCEG_01894 HCEG_02786 HCEG_02786 HCEG_03800 HCEG_03800 HCEG_03858 HCEG_03858 HCEG_03899 HCEG_03899 HCEG_03939 HCEG_03939 HCEG_04057 HCEG_04057 HCEG_04086 HCEG_04086 HCEG_03309 HCEG_03309 HCEG_03594 HCEG_03594 HCEG_05477 HCEG_05477 HCEG_05531 HCEG_05531 HCEG_05557 HCEG_05557 HCEG_05615 HCEG_05615 HCEG_04882 HCEG_04882 HCEG_04982 HCEG_04982 HCEG_05836 HCEG_05836 HCEG_05921 HCEG_05921 HCEG_07244 HCEG_07244 HCEG_06463 HCEG_06463 HCEG_06528 HCEG_06528 HCEG_07349 HCEG_07349 HCEG_06566 HCEG_06566 HCEG_06588 HCEG_06588 HCEG_06669 HCEG_06669 HCEG_06762 HCEG_06762 NBP35 NBP35 HCEG_06846 HCEG_06846 HCEG_06852 HCEG_06852 HCEG_06861 HCEG_06861 HCEG_06922 HCEG_06922 HCEG_06099 HCEG_06099 cprA cprA HCEG_07013 HCEG_07013 HCEG_07075 HCEG_07075 CFD1 CFD1 HCEG_07087 HCEG_07087 MET3 MET3 HCEG_07101 HCEG_07101 HCEG_07110 HCEG_07110 HCEG_06297 HCEG_06297 HCEG_07651 HCEG_07651 HCEG_07758 HCEG_07758 HCEG_07886 HCEG_07886 HCEG_07900 HCEG_07900 HCEG_07917 HCEG_07917 DRE2 DRE2 HCEG_07958 HCEG_07958 CIA1 CIA1 HCEG_07992 HCEG_07992 HCEG_08091 HCEG_08091 HCEG_08177 HCEG_08177 HCEG_08543 HCEG_08543 HCEG_08547 HCEG_08547 HCEG_08564 HCEG_08564 HCEG_08597 HCEG_08597 HCEG_08621 HCEG_08621 HCEG_08773 HCEG_08773 HCEG_08812 HCEG_08812
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCEG_00656Mitochondrial iron uptake protein. (228 aa)
hxBMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (861 aa)
HCEG_00037Monothiol glutaredoxin-4. (278 aa)
HCEG_00909MOSC domain-containing protein. (485 aa)
HCEG_00926Bis(5'-adenosyl)-triphosphatase. (182 aa)
HCEG_01778PH domain-containing protein. (841 aa)
HCEG_00956Nitrate reductase. (1034 aa)
HCEG_01809BolA domain-containing protein; Belongs to the BolA/IbaG family. (94 aa)
HCEG_01127RING finger domain-containing protein. (364 aa)
HCEG_00380Inositol phospholipid biosynthesis protein Scs3. (311 aa)
HCEG_01235MOSC domain-containing protein. (380 aa)
HCEG_01287Iron-sulfur cluster assembly protein. (142 aa)
HCEG_01320Monothiol glutaredoxin-5. (117 aa)
HCEG_02871Oligonucleotide transporter. (325 aa)
HCEG_02872Oligonucleotide transporter. (414 aa)
HCEG_03074Uncharacterized protein. (187 aa)
HCEG_03094Essential protein Yae1. (241 aa)
HCEG_02324Iron-sulfur cluster assembly protein; Belongs to the NARF family. (632 aa)
HCEG_02464Uncharacterized protein. (394 aa)
HCEG_02465Iron-sulfur cluster assembly protein. (236 aa)
HCEG_02538Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (216 aa)
HCEG_01894Bifunctional P-450:NADPH-P450 reductase; Belongs to the cytochrome P450 family. (457 aa)
HCEG_02786N2227 domain-containing protein. (421 aa)
HCEG_03800Porphobilinogen deaminase. (352 aa)
HCEG_03858DnaJ domain-containing protein. (279 aa)
HCEG_03899Bis(5'-nucleosyl)-tetraphosphatase. (350 aa)
HCEG_03939DNA repair/transcription protein. (1045 aa)
HCEG_04057Electron transfer flavoprotein beta-subunit. (899 aa)
HCEG_04086Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (427 aa)
HCEG_03309Molybdopterin cofactor biosynthetic protein. (769 aa)
HCEG_03594DUF614 domain-containing protein. (301 aa)
HCEG_05477Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (323 aa)
HCEG_05531NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (321 aa)
HCEG_05557HIRA-interacting protein. (314 aa)
HCEG_05615Riboflavin kinase. (227 aa)
HCEG_04882Uncharacterized protein. (734 aa)
HCEG_04982Uncharacterized protein. (210 aa)
HCEG_05836Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (156 aa)
HCEG_05921Siroheme biosynthesis protein MET8. (260 aa)
HCEG_07244FAD binding domain-containing protein. (643 aa)
HCEG_06463Ubiquitin-protein ligase molybdopterin-converting factor. (605 aa)
HCEG_06528Nitrate reductase. (855 aa)
HCEG_07349Coproporphyrinogen III oxidase. (422 aa)
HCEG_06566Uncharacterized protein. (776 aa)
HCEG_06588FeS_assembly_P domain-containing protein. (206 aa)
HCEG_06669Molybdopterin binding domain-containing protein. (335 aa)
HCEG_06762Mitochondrial NADH dehydrogenase. (681 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (363 aa)
HCEG_06846DUF323 domain-containing protein. (816 aa)
HCEG_06852Sulfite reductase beta subunit. (1535 aa)
HCEG_06861Molybdenum cofactor biosynthesis protein; Belongs to the V-ATPase proteolipid subunit family. (1075 aa)
HCEG_06922FAD synthetase. (323 aa)
HCEG_06099Sulfite oxidase. (403 aa)
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (694 aa)
HCEG_07013Cysteine desulfurase. (799 aa)
HCEG_07075Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (549 aa)
CFD1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (407 aa)
HCEG_07087LYR family protein; Belongs to the complex I LYR family. (758 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
HCEG_071013'-phosphoadenosine-5'-phosphosulfate reductase. (300 aa)
HCEG_07110Uroporphyrin methyltransferase; Belongs to the precorrin methyltransferase family. (568 aa)
HCEG_062972Fe-2S cluster binding domain-containing protein. (214 aa)
HCEG_07651Cysteine desulfurase. (543 aa)
HCEG_07758Iron-sulfur cluster assembly protein. (236 aa)
HCEG_07886BolA domain-containing protein; Belongs to the BolA/IbaG family. (137 aa)
HCEG_07900Thiosulfate sulfurtransferase. (341 aa)
HCEG_07917MOSC domain-containing protein. (197 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (351 aa)
HCEG_07958Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (378 aa)
CIA1Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (485 aa)
HCEG_07992Yae1_N domain-containing protein. (258 aa)
HCEG_08091Uncharacterized protein. (121 aa)
HCEG_08177Uncharacterized protein. (156 aa)
HCEG_085433',5'-bisphosphate nucleotidase. (353 aa)
HCEG_08547Sulfite reductase flavoprotein component. (1082 aa)
HCEG_08564Sugar isomerase. (455 aa)
HCEG_08597ATPase. (336 aa)
HCEG_08621Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (137 aa)
HCEG_08773Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (595 aa)
HCEG_08812Aminotransferase. (573 aa)
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
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