58 items (Histoplasma capsulatum H88) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCEG_00514	Uncharacterized protein. (377 aa)
	HCEG_01369	Fungal specific transcription factor domain-containing protein. (766 aa)
	HCEG_01401	Protein kinase domain-containing protein. (252 aa)
	HCEG_01525	Uncharacterized protein. (126 aa)
	HCEG_01543	Serine/threonine protein kinase ssp1. (1216 aa)
	HCEG_01558	CBS and PB1 domain-containing protein. (668 aa)
	HCEG_01570	CBS domain-containing protein; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (540 aa)
	HCEG_00760	Uncharacterized protein. (114 aa)
	HCEG_00790	C-x8-C-x5-C-x3-H zinc finger protein. (582 aa)
	HCEG_01607	Uncharacterized protein. (377 aa)
	HCEG_00824	Serine/threonine protein kinase. (1019 aa)
	HCEG_01684	Calmodulin-binding coil-coil protein. (1234 aa)
	HCEG_01789	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (966 aa)
	HCEG_00196	ATG11 domain-containing protein. (1303 aa)
	HCEG_00311	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (415 aa)
	HCEG_02016	Protein kinase. (987 aa)
	HCEG_02897	Protein kinase domain-containing protein. (309 aa)
	HCEG_02569	Non-specific serine/threonine protein kinase. (955 aa)
	HCEG_02677	Protein phosphatase type 1 complex subunit Hex2/Reg1. (638 aa)
	HCEG_03701	Zn(2)-C6 fungal-type domain-containing protein. (621 aa)
	HCEG_04558	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (333 aa)
	HCEG_03752	ATG16 domain-containing protein. (208 aa)
	HCEG_03922	Uncharacterized protein. (550 aa)
	HCEG_04227	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (508 aa)
	HCEG_04320	Protein kinase. (202 aa)
	HCEG_04334	Calcium/calmodulin-dependent protein kinase. (800 aa)
	HCEG_04405	Non-specific serine/threonine protein kinase. (837 aa)
	HCEG_03600	UV radiation resistance protein. (550 aa)
	HCEG_04469	AGC family protein kinase. (427 aa)
	HCEG_03647	Nuclear protein SNF4. (379 aa)
	HCEG_03648	Uncharacterized protein. (674 aa)
	HCEG_04615	Glycosyl hydrolase. (513 aa)
	HCEG_05804	Kinase activator. (587 aa)
	HCEG_05300	Glycosyl hydrolase. (382 aa)
	HCEG_05357	Protein phosphatase; Belongs to the PP2C family. (397 aa)
	HCEG_07208	Serine/threonine protein kinase DCLK1. (636 aa)
	HCEG_06453	Phosphatidylinositol 3-kinase VPS34. (912 aa)
	HCEG_06481	SVP1-like protein. (370 aa)
	HCEG_07347	Autophagy-related protein. (118 aa)
	HCEG_06609	Vacuolar targeting protein Atg18. (438 aa)
	HCEG_06872	Protein kinase domain-containing protein. (257 aa)
	HCEG_06903	Uncharacterized protein. (1626 aa)
	HCEG_06927	Predicted protein. (99 aa)
	HCEG_06928	Predicted protein. (166 aa)
	HCEG_07119	Calcium/calmodulin dependent protein kinase. (302 aa)
	HCEG_07490	Meiosis protein MEI2. (677 aa)
	HCEG_07602	Snf1 kinase complex beta-subunit Gal83. (552 aa)
	HCEG_07947	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (702 aa)
	HCEG_08096	Serine/threonine protein kinase ksp1. (643 aa)
	HCEG_08140	DUF1649 domain-containing protein. (245 aa)
	HCEG_08149	Autophagy-related protein 3. (378 aa)
	HCEG_08562	BTB domain-containing protein. (341 aa)
	HCEG_08580	Uncharacterized protein. (528 aa)
	HCEG_08634	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (665 aa)
	HCEG_08635	Uncharacterized protein. (86 aa)
	HCEG_08664	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (179 aa)
	HCEG_08940	Autophagy protein Atg2. (2159 aa)
	HCEG_09293	Autophagy_act_C domain-containing protein. (265 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_00196	HCEG_00760	F0U812	F0U607	ATG11 domain-containing protein.	Uncharacterized protein.	0.506
HCEG_00196	HCEG_00824	F0U812	F0U6C6	ATG11 domain-containing protein.	Serine/threonine protein kinase.	0.986
HCEG_00196	HCEG_01789	F0U812	F0U7G0	ATG11 domain-containing protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.987
HCEG_00196	HCEG_02016	F0U812	F0UA29	ATG11 domain-containing protein.	Protein kinase.	0.575
HCEG_00196	HCEG_02569	F0U812	F0UCS8	ATG11 domain-containing protein.	Non-specific serine/threonine protein kinase.	0.528
HCEG_00196	HCEG_03647	F0U812	F0UH85	ATG11 domain-containing protein.	Nuclear protein SNF4.	0.477
HCEG_00196	HCEG_03648	F0U812	F0UH86	ATG11 domain-containing protein.	Uncharacterized protein.	0.477
HCEG_00196	HCEG_03922	F0U812	F0UEH7	ATG11 domain-containing protein.	Uncharacterized protein.	0.765
HCEG_00196	HCEG_04227	F0U812	F0UFW3	ATG11 domain-containing protein.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.	0.510
HCEG_00196	HCEG_04405	F0U812	F0UGV1	ATG11 domain-containing protein.	Non-specific serine/threonine protein kinase.	0.544
HCEG_00196	HCEG_04469	F0U812	F0UH67	ATG11 domain-containing protein.	AGC family protein kinase.	0.587
HCEG_00196	HCEG_04558	F0U812	F0UDY2	ATG11 domain-containing protein.	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	0.511
HCEG_00196	HCEG_04615	F0U812	F0UHI9	ATG11 domain-containing protein.	Glycosyl hydrolase.	0.480
HCEG_00196	HCEG_05300	F0U812	F0UKY1	ATG11 domain-containing protein.	Glycosyl hydrolase.	0.480
HCEG_00196	HCEG_05804	F0U812	F0UJJ8	ATG11 domain-containing protein.	Kinase activator.	0.891
HCEG_00196	HCEG_06453	F0U812	F0UM41	ATG11 domain-containing protein.	Phosphatidylinositol 3-kinase VPS34.	0.715
HCEG_00196	HCEG_06609	F0U812	F0UMS7	ATG11 domain-containing protein.	Vacuolar targeting protein Atg18.	0.520
HCEG_00196	HCEG_06903	F0U812	F0UNY4	ATG11 domain-containing protein.	Uncharacterized protein.	0.679
HCEG_00196	HCEG_07347	F0U812	F0UME0	ATG11 domain-containing protein.	Autophagy-related protein.	0.546
HCEG_00196	HCEG_07947	F0U812	F0US55	ATG11 domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.655