(92 nodes) Mixed, incl. Cytochrome P450 - arranged by substrate type, and AMP-binding enzyme network (Histoplasma capsulatum H88)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCEG_00583	Thiol methyltransferase. (284 aa)
	HCEG_01429	Cytochrome P450. (555 aa)
	HCEG_01438	Peroxisomal CoA synthetase. (513 aa)
	HCEG_00651	Uncharacterized protein. (498 aa)
	HCEG_00686	AMP binding enzyme. (539 aa)
	HCEG_01484	Uncharacterized protein. (330 aa)
	HCEG_00017	Methyltransf_11 domain-containing protein. (950 aa)
	HCEG_00068	Nonribosomal peptide synthetase. (1955 aa)
	HCEG_00906	GA14-synthase; Belongs to the cytochrome P450 family. (524 aa)
	HCEG_01792	Cytochrome P450; Belongs to the cytochrome P450 family. (598 aa)
	HCEG_00160	Uncharacterized protein. (1146 aa)
	HCEG_01089	Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa)
	HCEG_00295	Iterative type I polyketide synthase. (2645 aa)
	HCEG_00350	AMP dependent synthetase and ligase. (581 aa)
	HCEG_01251	Nonribosomal peptide synthase. (516 aa)
	HCEG_01252	Nonribosomal peptide synthetase. (4322 aa)
	HCEG_00450	Uncharacterized protein. (236 aa)
	HCEG_02007	FK506 suppressor Sfk1. (102 aa)
	HCEG_02895	Predicted protein. (227 aa)
	HCEG_02904	Predicted protein. (323 aa)
	HCEG_02982	Uncharacterized protein. (267 aa)
	HCEG_03006	D-lysergyl-peptide-synthetase. (1949 aa)
	HCEG_02235	4-coumarate-CoA ligase. (142 aa)
	HCEG_02251	FAD binding domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (593 aa)
	HCEG_02279	Uncharacterized protein. (753 aa)
	HCEG_03182	Benzoate 4-monooxygenase cytochrome P450. (508 aa)
	HCEG_03189	AMP-binding domain-containing protein. (755 aa)
	HCEG_03210	Phenylacetyl-CoA ligase. (557 aa)
	HCEG_02600	Fatty acid synthase. (82 aa)
	HCEG_02616	Nonribosomal peptide synthase. (2502 aa)
	HCEG_02631	Uncharacterized protein; Belongs to the cytochrome P450 family. (506 aa)
	HCEG_03692	Cytochrome P450. (404 aa)
	HCEG_03696	Polyketide synthase. (2335 aa)
	HCEG_03783	Phosphotransferase enzyme family protein. (323 aa)
	HCEG_03857	Uncharacterized protein. (488 aa)
	HCEG_03891	Uncharacterized protein. (438 aa)
	HCEG_03892	Uncharacterized protein. (140 aa)
	HCEG_03896	MFS transporter. (610 aa)
	HCEG_03945	Oxidoreductase. (327 aa)
	HCEG_03947	Nonribosomal peptide synthetase. (1276 aa)
	HCEG_03948	Uncharacterized protein. (330 aa)
	HCEG_04002	AMP dependent CoA ligase. (582 aa)
	HCEG_04070	APH domain-containing protein. (507 aa)
	HCEG_04147	APH domain-containing protein. (520 aa)
	HCEG_04176	FAD binding domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (631 aa)
	HCEG_03405	VWFA domain-containing protein. (283 aa)
	HCEG_03491	Carrier domain-containing protein. (1039 aa)
	HCEG_03544	Meiotically up-regulated gene 62 protein. (1889 aa)
	HCEG_03563	Peroxin 11C. (350 aa)
	HCEG_03690	Uncharacterized protein. (292 aa)
	HCEG_04666	Antibiotic synthetase. (1016 aa)
	HCEG_04772	Uncharacterized protein. (429 aa)
	HCEG_04825	Uncharacterized protein. (716 aa)
	HCEG_05778	Sterigmatocystin biosynthesis P450 monooxygenase StcS; Belongs to the cytochrome P450 family. (554 aa)
	HCEG_05785	F-box domain-containing protein. (723 aa)
	HCEG_05839	Phosphotransferase enzyme family protein. (322 aa)
	HCEG_05925	Cytochrome P450. (530 aa)
	HCEG_05409	MesA protein. (787 aa)
	HCEG_07290	Isoamyl alcohol oxidase; Belongs to the oxygen-dependent FAD-linked oxidoreductase family. (587 aa)
	HCEG_07304	Armadillo repeat protein. (997 aa)
	HCEG_07310	Glyoxalase/bleomycin resistance protein/dioxygenase. (157 aa)
	HCEG_06665	Short-chain dehydrogenase/reductase. (325 aa)
	HCEG_06712	Short-chain dehydrogenase. (340 aa)
	HCEG_06804	Benzoate 4-monooxygenase cytochrome P450. (506 aa)
	HCEG_06855	Uncharacterized protein. (462 aa)
	HCEG_06857	Uncharacterized protein. (400 aa)
	HCEG_06094	Benzoate 4-monooxygenase cytochrome P450; Belongs to the cytochrome P450 family. (536 aa)
	HCEG_06115	Oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (338 aa)
	HCEG_06282	AMP-binding domain-containing protein. (705 aa)
	HCEG_07104	Short chain alcohol dehydrogenase. (401 aa)
	HCEG_07141	Glyoxalase. (598 aa)
	HCEG_07150	4-coumarate-CoA ligase. (616 aa)
	HCEG_07462	Cytochrome P450; Belongs to the cytochrome P450 family. (492 aa)
	HCEG_07497	DDE_Tnp_1_7 domain-containing protein. (211 aa)
	HCEG_07589	Short chain dehydrogenase/reductase. (375 aa)
	HCEG_07694	Benzoate 4-monooxygenase cytochrome P450. (495 aa)
	HCEG_07869	Fungal specific transcription factor domain-containing protein. (709 aa)
	HCEG_07871	AMP dependent synthetase and ligase. (341 aa)
	HCEG_07916	F-box domain-containing protein. (710 aa)
	HCEG_08046	Uncharacterized protein; Belongs to the cytochrome P450 family. (514 aa)
	HCEG_08104	Uncharacterized protein. (943 aa)
	HCEG_08168	Uncharacterized protein. (943 aa)
	HCEG_08188	Uncharacterized protein. (513 aa)
	HCEG_08411	Cytochrome P450; Belongs to the cytochrome P450 family. (490 aa)
	cnxH	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the cytochrome P450 family. (423 aa)
	HCEG_08528	Uncharacterized protein. (297 aa)
	HCEG_09009	Short chain dehydrogenase/reductase. (411 aa)
	HCEG_09203	UV-damage endonuclease. (704 aa)
	HCEG_09204	Actin patch protein. (877 aa)
	HCEG_09323	Polyketide synthase. (2479 aa)
	HCEG_09324	Phenylacetyl-CoA ligase. (560 aa)
	HCEG_09326	Peptide synthetase. (5717 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_00017	HCEG_00068	F0U6L6	F0U724	Methyltransf_11 domain-containing protein.	Nonribosomal peptide synthetase.	0.551
HCEG_00017	HCEG_00160	F0U6L6	F0U7M1	Methyltransf_11 domain-containing protein.	Uncharacterized protein.	0.543
HCEG_00017	HCEG_00295	F0U6L6	F0U8M8	Methyltransf_11 domain-containing protein.	Iterative type I polyketide synthase.	0.483
HCEG_00017	HCEG_00350	F0U6L6	F0U8Y6	Methyltransf_11 domain-containing protein.	AMP dependent synthetase and ligase.	0.543
HCEG_00017	HCEG_00686	F0U6L6	F0U5H6	Methyltransf_11 domain-containing protein.	AMP binding enzyme.	0.543
HCEG_00017	HCEG_01251	F0U6L6	F0U9E7	Methyltransf_11 domain-containing protein.	Nonribosomal peptide synthase.	0.560
HCEG_00017	HCEG_01252	F0U6L6	F0U9E8	Methyltransf_11 domain-containing protein.	Nonribosomal peptide synthetase.	0.560
HCEG_00017	HCEG_01438	F0U6L6	F0U585	Methyltransf_11 domain-containing protein.	Peroxisomal CoA synthetase.	0.591
HCEG_00017	HCEG_02235	F0U6L6	F0UBB1	Methyltransf_11 domain-containing protein.	4-coumarate-CoA ligase.	0.591
HCEG_00017	HCEG_02279	F0U6L6	F0UBK8	Methyltransf_11 domain-containing protein.	Uncharacterized protein.	0.591
HCEG_00017	HCEG_02600	F0U6L6	F0UCV9	Methyltransf_11 domain-containing protein.	Fatty acid synthase.	0.734
HCEG_00017	HCEG_02616	F0U6L6	F0UCX5	Methyltransf_11 domain-containing protein.	Nonribosomal peptide synthase.	0.551
HCEG_00017	HCEG_02982	F0U6L6	F0UAW0	Methyltransf_11 domain-containing protein.	Uncharacterized protein.	0.483
HCEG_00017	HCEG_03006	F0U6L6	F0UAY4	Methyltransf_11 domain-containing protein.	D-lysergyl-peptide-synthetase.	0.551
HCEG_00017	HCEG_03189	F0U6L6	F0UC28	Methyltransf_11 domain-containing protein.	AMP-binding domain-containing protein.	0.551
HCEG_00017	HCEG_03210	F0U6L6	F0UC49	Methyltransf_11 domain-containing protein.	Phenylacetyl-CoA ligase.	0.591
HCEG_00017	HCEG_03491	F0U6L6	F0UGC3	Methyltransf_11 domain-containing protein.	Carrier domain-containing protein.	0.551
HCEG_00017	HCEG_03544	F0U6L6	F0UGM9	Methyltransf_11 domain-containing protein.	Meiotically up-regulated gene 62 protein.	0.543
HCEG_00017	HCEG_03696	F0U6L6	F0UDQ8	Methyltransf_11 domain-containing protein.	Polyketide synthase.	0.483
HCEG_00017	HCEG_03857	F0U6L6	F0UEB2	Methyltransf_11 domain-containing protein.	Uncharacterized protein.	0.483