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MED8 MED8 MED5 MED5 MED18 MED18 HCEG_00759 HCEG_00759 MED9 MED9 HCEG_00150 HCEG_00150 HCEG_01111 HCEG_01111 MED10 MED10 HCEG_00381 HCEG_00381 HCEG_01218 HCEG_01218 MED16 MED16 HCEG_02287 HCEG_02287 HCEG_02613 HCEG_02613 HCEG_03766 HCEG_03766 HCEG_04018 HCEG_04018 MED17 MED17 HCEG_05502 HCEG_05502 HCEG_05572 HCEG_05572 HCEG_05261 HCEG_05261 MED11 MED11 MED20 MED20 HCEG_06821 HCEG_06821 HCEG_06090 HCEG_06090 HCEG_06957 HCEG_06957 HCEG_06148 HCEG_06148 HCEG_07042 HCEG_07042 HCEG_07088 HCEG_07088 HCEG_07627 HCEG_07627 HCEG_07709 HCEG_07709 HCEG_07887 HCEG_07887 HCEG_08057 HCEG_08057 HCEG_08619 HCEG_08619 HCEG_08641 HCEG_08641 HCEG_08819 HCEG_08819 HCEG_08993 HCEG_08993 HCEG_09156 HCEG_09156 MED4 MED4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (256 aa)
MED5Mediator of RNA polymerase II transcription subunit 5; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (999 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (274 aa)
HCEG_00759Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (753 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (209 aa)
HCEG_00150Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (172 aa)
HCEG_01111Uncharacterized protein. (117 aa)
MED10Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (158 aa)
HCEG_00381Uncharacterized protein. (336 aa)
HCEG_01218C6 zinc finger domain-containing protein. (1078 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (944 aa)
HCEG_02287PAP2 domain-containing protein. (388 aa)
HCEG_02613Cytochrome P450 oxidoreductase; Belongs to the cytochrome P450 family. (508 aa)
HCEG_03766Nitrogen assimilation transcription factor nirA. (905 aa)
HCEG_04018AMP dependent CoA ligase. (550 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (695 aa)
HCEG_05502Benzoate 4-monooxygenase cytochrome P450. (539 aa)
HCEG_05572Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1071 aa)
HCEG_05261Benzoate 4-monooxygenase cytochrome P450; Belongs to the cytochrome P450 family. (440 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (171 aa)
MED20Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (369 aa)
HCEG_06821Cyclin; Belongs to the cyclin family. (301 aa)
HCEG_06090AMP dependent CoA ligase. (533 aa)
HCEG_06957Meiotic mRNA stability protein kinase UME5. (428 aa)
HCEG_06148Trichothecene C-15 hydroxylase; Belongs to the cytochrome P450 family. (507 aa)
HCEG_07042RNA polymerase II mediator complex component Srb8. (1569 aa)
HCEG_07088Uncharacterized protein. (249 aa)
HCEG_07627RNA polymerase II transcription mediator complex subunit. (398 aa)
HCEG_07709N-alkane-inducible cytochrome P450. (504 aa)
HCEG_07887CoA synthetase. (630 aa)
HCEG_08057Cytochrome P450 monooxygenase; Belongs to the cytochrome P450 family. (449 aa)
HCEG_08619Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (253 aa)
HCEG_08641Mediator of RNA polymerase II transcription subunit 13; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. (1527 aa)
HCEG_08819Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (178 aa)
HCEG_08993Cytochrome P450 family protein; Belongs to the cytochrome P450 family. (406 aa)
HCEG_09156Uncharacterized protein. (153 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (339 aa)
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
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