(46 nodes) Steroid biosynthetic process, and Cutin, suberine and wax biosynthesis network (Histoplasma capsulatum H88)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	HCEG_00516	FAD binding domain-containing protein. (499 aa)
	HCEG_00758	C-3 sterol dehydrogenase/C-4 decarboxylase. (380 aa)
	HCEG_00805	Sterol desaturase; Belongs to the sterol desaturase family. (253 aa)
	HCEG_00873	Ergosterol biosynthetic protein. (133 aa)
	HCEG_00090	C-3 sterol dehydrogenase/C-4 decarboxylase. (426 aa)
	HCEG_01817	C-3 sterol dehydrogenase/C-4 decarboxylase. (352 aa)
	HCEG_01066	Secreted protein. (391 aa)
	HCEG_00388	C-14 sterol reductase. (503 aa)
	HCEG_01248	Cytochrome b5; Belongs to the cytochrome b5 family. (84 aa)
	HCEG_02953	QDE-2-interacting protein. (751 aa)
	HCEG_02970	Uncharacterized protein. (357 aa)
	HCEG_03125	FAD binding domain-containing protein. (660 aa)
	HCEG_02370	3-ketosteroid reductase. (456 aa)
	HCEG_03177	Cytochrome P450 monooxygenase; Belongs to the cytochrome P450 family. (494 aa)
	HCEG_02402	Uncharacterized protein. (333 aa)
	HCEG_02499	C-24(28) sterol reductase. (472 aa)
	HCEG_02560	Sterol desaturase; Belongs to the sterol desaturase family. (337 aa)
	HCEG_01898	Methyltransf_25 domain-containing protein. (280 aa)
	HCEG_02773	EXPERA domain-containing protein. (248 aa)
	HCEG_03864	7-dehydrosterol-delta 7-reductase. (459 aa)
	HCEG_04091	Squalene epoxidase. (484 aa)
	HCEG_03383	Inositolphosphorylceramide-B C-26 hydroxylase; Belongs to the cytochrome b5 family. (431 aa)
	HCEG_04628	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (380 aa)
	HCEG_04710	C4-methylsterol oxidase; Belongs to the sterol desaturase family. (249 aa)
	HCEG_05517	Uncharacterized protein; Belongs to the cytochrome P450 family. (583 aa)
	HCEG_05891	Zn(2)-C6 fungal-type domain-containing protein. (758 aa)
	HCEG_05132	Cytochrome P450 sterol 14 alpha-demethylase; Belongs to the cytochrome P450 family. (515 aa)
	HCEG_05442	NAD dependent epimerase/dehydratase. (374 aa)
	HCEG_06407	Triacylglycerol lipase. (519 aa)
	HCEG_07316	C-24(28) sterol reductase. (539 aa)
	HCEG_07340	Uncharacterized protein. (201 aa)
	HCEG_07016	C-8 sterol isomerase. (213 aa)
	HCEG_06301	O-methyltransferase. (248 aa)
	HCEG_06343	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (728 aa)
	HCEG_07463	Cytochrome P450; Belongs to the cytochrome P450 family. (505 aa)
	HCEG_07464	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (700 aa)
	HCEG_07513	C-5 sterol desaturase; Belongs to the sterol desaturase family. (356 aa)
	HCEG_07868	Squalene synthetase. (472 aa)
	HCEG_07940	Sterigmatocystin biosynthesis P450 monooxygenase StcS. (521 aa)
	HCEG_08078	Methyltransferase. (342 aa)
	HCEG_08276	Cytochrome P450 oxidoreductase; Belongs to the cytochrome P450 family. (500 aa)
	HCEG_08776	Cytochrome P450 alkane hydroxylase. (471 aa)
	HCEG_08874	Cytochrome P450 sterol C-22 desaturase; Belongs to the cytochrome P450 family. (533 aa)
	HCEG_09279	C-4 methylsterol oxidase; Belongs to the sterol desaturase family. (239 aa)
	HCEG_09325	Uncharacterized protein; Belongs to the cytochrome P450 family. (600 aa)
	HCEG_09351	Serine/threonine protein kinase chk2; Belongs to the cytochrome P450 family. (1213 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_00090	HCEG_00388	F0U746	F0U976	C-3 sterol dehydrogenase/C-4 decarboxylase.	C-14 sterol reductase.	0.783
HCEG_00090	HCEG_00758	F0U746	F0U605	C-3 sterol dehydrogenase/C-4 decarboxylase.	C-3 sterol dehydrogenase/C-4 decarboxylase.	0.755
HCEG_00090	HCEG_00805	F0U746	F0U6A7	C-3 sterol dehydrogenase/C-4 decarboxylase.	Sterol desaturase; Belongs to the sterol desaturase family.	0.810
HCEG_00090	HCEG_00873	F0U746	F0U6T2	C-3 sterol dehydrogenase/C-4 decarboxylase.	Ergosterol biosynthetic protein.	0.874
HCEG_00090	HCEG_01066	F0U746	F0U8F4	C-3 sterol dehydrogenase/C-4 decarboxylase.	Secreted protein.	0.509
HCEG_00090	HCEG_01817	F0U746	F0U7U3	C-3 sterol dehydrogenase/C-4 decarboxylase.	C-3 sterol dehydrogenase/C-4 decarboxylase.	0.824
HCEG_00090	HCEG_02370	F0U746	F0UC02	C-3 sterol dehydrogenase/C-4 decarboxylase.	3-ketosteroid reductase.	0.990
HCEG_00090	HCEG_02402	F0U746	F0UC87	C-3 sterol dehydrogenase/C-4 decarboxylase.	Uncharacterized protein.	0.509
HCEG_00090	HCEG_02499	F0U746	F0UCK8	C-3 sterol dehydrogenase/C-4 decarboxylase.	C-24(28) sterol reductase.	0.766
HCEG_00090	HCEG_02560	F0U746	F0UCR9	C-3 sterol dehydrogenase/C-4 decarboxylase.	Sterol desaturase; Belongs to the sterol desaturase family.	0.810
HCEG_00090	HCEG_02970	F0U746	F0UAU8	C-3 sterol dehydrogenase/C-4 decarboxylase.	Uncharacterized protein.	0.509
HCEG_00090	HCEG_03177	F0U746	F0UC16	C-3 sterol dehydrogenase/C-4 decarboxylase.	Cytochrome P450 monooxygenase; Belongs to the cytochrome P450 family.	0.509
HCEG_00090	HCEG_03864	F0U746	F0UEB9	C-3 sterol dehydrogenase/C-4 decarboxylase.	7-dehydrosterol-delta 7-reductase.	0.783
HCEG_00090	HCEG_04091	F0U746	F0UF19	C-3 sterol dehydrogenase/C-4 decarboxylase.	Squalene epoxidase.	0.909
HCEG_00090	HCEG_04628	F0U746	F0UHK2	C-3 sterol dehydrogenase/C-4 decarboxylase.	Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.	0.865
HCEG_00090	HCEG_04710	F0U746	F0UHY6	C-3 sterol dehydrogenase/C-4 decarboxylase.	C4-methylsterol oxidase; Belongs to the sterol desaturase family.	0.991
HCEG_00090	HCEG_05132	F0U746	F0UKD0	C-3 sterol dehydrogenase/C-4 decarboxylase.	Cytochrome P450 sterol 14 alpha-demethylase; Belongs to the cytochrome P450 family.	0.882
HCEG_00090	HCEG_05517	F0U746	F0UHZ7	C-3 sterol dehydrogenase/C-4 decarboxylase.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.722
HCEG_00090	HCEG_05891	F0U746	F0UK41	C-3 sterol dehydrogenase/C-4 decarboxylase.	Zn(2)-C6 fungal-type domain-containing protein.	0.652
HCEG_00090	HCEG_06343	F0U746	F0UQD0	C-3 sterol dehydrogenase/C-4 decarboxylase.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.788