30 items (Histoplasma capsulatum H88) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCEG_03636	Armadillo repeat protein. (580 aa)
	HCEG_04227	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (508 aa)
	HCEG_03922	Uncharacterized protein. (550 aa)
	HCEG_03752	ATG16 domain-containing protein. (208 aa)
	HCEG_08149	Autophagy-related protein 3. (378 aa)
	HCEG_08634	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (665 aa)
	HCEG_08635	Uncharacterized protein. (86 aa)
	HCEG_08664	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (179 aa)
	HCEG_08940	Autophagy protein Atg2. (2159 aa)
	HCEG_07457	GTP-binding protein ypt1. (205 aa)
	HCEG_07896	Uncharacterized protein. (463 aa)
	HCEG_07947	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (702 aa)
	HCEG_08140	DUF1649 domain-containing protein. (245 aa)
	HCEG_06609	Vacuolar targeting protein Atg18. (438 aa)
	HCEG_09293	Autophagy_act_C domain-containing protein. (265 aa)
	HCEG_04558	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (333 aa)
	HCEG_02780	Uncharacterized protein. (310 aa)
	HCEG_02104	ZZ type zinc finger domain-containing protein. (846 aa)
	HCEG_00824	Serine/threonine protein kinase. (1019 aa)
	HCEG_03040	Uncharacterized protein. (611 aa)
	HCEG_01703	UDP-glucose:sterol glycosyltransferase. (1468 aa)
	HCEG_01789	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (966 aa)
	HCEG_00196	ATG11 domain-containing protein. (1303 aa)
	HCEG_06595	Uncharacterized protein. (536 aa)
	HCEG_07373	Uncharacterized protein; Belongs to the CTL (choline transporter-like) family. (785 aa)
	HCEG_06481	SVP1-like protein. (370 aa)
	HCEG_06453	Phosphatidylinositol 3-kinase VPS34. (912 aa)
	HCEG_04576	Viral A-type inclusion protein repeat protein. (1194 aa)
	HCEG_05804	Kinase activator. (587 aa)
	HCEG_04469	AGC family protein kinase. (427 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_00196	HCEG_00824	F0U812	F0U6C6	ATG11 domain-containing protein.	Serine/threonine protein kinase.	0.986
HCEG_00196	HCEG_01703	F0U812	F0U6X0	ATG11 domain-containing protein.	UDP-glucose:sterol glycosyltransferase.	0.438
HCEG_00196	HCEG_01789	F0U812	F0U7G0	ATG11 domain-containing protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.987
HCEG_00196	HCEG_03636	F0U812	F0UH22	ATG11 domain-containing protein.	Armadillo repeat protein.	0.582
HCEG_00196	HCEG_03922	F0U812	F0UEH7	ATG11 domain-containing protein.	Uncharacterized protein.	0.765
HCEG_00196	HCEG_04227	F0U812	F0UFW3	ATG11 domain-containing protein.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.	0.510
HCEG_00196	HCEG_04469	F0U812	F0UH67	ATG11 domain-containing protein.	AGC family protein kinase.	0.587
HCEG_00196	HCEG_04558	F0U812	F0UDY2	ATG11 domain-containing protein.	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	0.511
HCEG_00196	HCEG_05804	F0U812	F0UJJ8	ATG11 domain-containing protein.	Kinase activator.	0.891
HCEG_00196	HCEG_06453	F0U812	F0UM41	ATG11 domain-containing protein.	Phosphatidylinositol 3-kinase VPS34.	0.715
HCEG_00196	HCEG_06609	F0U812	F0UMS7	ATG11 domain-containing protein.	Vacuolar targeting protein Atg18.	0.520
HCEG_00196	HCEG_07457	F0U812	F0UQR5	ATG11 domain-containing protein.	GTP-binding protein ypt1.	0.478
HCEG_00196	HCEG_07947	F0U812	F0US55	ATG11 domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.655
HCEG_00196	HCEG_08140	F0U812	F0USP8	ATG11 domain-containing protein.	DUF1649 domain-containing protein.	0.948
HCEG_00196	HCEG_08149	F0U812	F0USQ7	ATG11 domain-containing protein.	Autophagy-related protein 3.	0.511
HCEG_00196	HCEG_08634	F0U812	F0UU42	ATG11 domain-containing protein.	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily.	0.964
HCEG_00196	HCEG_08635	F0U812	F0UU43	ATG11 domain-containing protein.	Uncharacterized protein.	0.842
HCEG_00196	HCEG_08664	F0U812	F0UU72	ATG11 domain-containing protein.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	0.637
HCEG_00196	HCEG_08940	F0U812	F0UUZ8	ATG11 domain-containing protein.	Autophagy protein Atg2.	0.511
HCEG_00824	HCEG_00196	F0U6C6	F0U812	Serine/threonine protein kinase.	ATG11 domain-containing protein.	0.986