STRINGSTRING
HCEG_06134 HCEG_06134 HCEG_00503 HCEG_00503 HCEG_01348 HCEG_01348 HCEG_01365 HCEG_01365 HCEG_01397 HCEG_01397 HCEG_00608 HCEG_00608 HCEG_00625 HCEG_00625 HCEG_00630 HCEG_00630 HCEG_01432 HCEG_01432 HCEG_01451 HCEG_01451 HCEG_01510 HCEG_01510 HCEG_01528 HCEG_01528 HCEG_00693 HCEG_00693 HCEG_00694 HCEG_00694 HCEG_00695 HCEG_00695 HCEG_01540 HCEG_01540 HCEG_01634 HCEG_01634 HCEG_00807 HCEG_00807 HCEG_01679 HCEG_01679 HCEG_00019 HCEG_00019 HCEG_00041 HCEG_00041 HCEG_01743 HCEG_01743 HCEG_00908 HCEG_00908 HCEG_00927 HCEG_00927 NTH1 NTH1 HCEG_01756 HCEG_01756 HCEG_01760 HCEG_01760 HCEG_01761 HCEG_01761 HCEG_01781 HCEG_01781 HCEG_00155 HCEG_00155 HCEG_01827 HCEG_01827 HCEG_00179 HCEG_00179 HCEG_00199 HCEG_00199 HCEG_01097 HCEG_01097 HCEG_00319 HCEG_00319 HCEG_01115 HCEG_01115 HCEG_01151 HCEG_01151 HCEG_00465 HCEG_00465 HCEG_01304 HCEG_01304 HCEG_01982 HCEG_01982 HCEG_01985 HCEG_01985 HCEG_02800 HCEG_02800 HCEG_02823 HCEG_02823 HCEG_02846 HCEG_02846 HCEG_02033 HCEG_02033 HCEG_02058 HCEG_02058 HCEG_02071 HCEG_02071 HCEG_02916 HCEG_02916 HCEG_02964 HCEG_02964 HCEG_02181 HCEG_02181 HCEG_02186 HCEG_02186 HCEG_02196 HCEG_02196 HCEG_02199 HCEG_02199 HCEG_03023 HCEG_03023 HCEG_03038 HCEG_03038 HCEG_03053 HCEG_03053 HCEG_03103 HCEG_03103 HCEG_02297 HCEG_02297 HCEG_02315 HCEG_02315 HCEG_02322 HCEG_02322 HCEG_03144 HCEG_03144 HCEG_03145 HCEG_03145 HCEG_02351 HCEG_02351 HCEG_02358 HCEG_02358 MCM7 MCM7 HCEG_02404 HCEG_02404 HCEG_02405 HCEG_02405 HCEG_03223 HCEG_03223 HCEG_02436 HCEG_02436 HCEG_02441 HCEG_02441 HCEG_02461 HCEG_02461 HCEG_02467 HCEG_02467 HCEG_02477 HCEG_02477 HCEG_02479 HCEG_02479 HCEG_02555 HCEG_02555 HCEG_02556 HCEG_02556 HCEG_02649 HCEG_02649 HCEG_02675 HCEG_02675 HCEG_01865 HCEG_01865 HCEG_02708 HCEG_02708 HCEG_02758 HCEG_02758 HCEG_02775 HCEG_02775 HCEG_04557 HCEG_04557 HCEG_03750 HCEG_03750 HCEG_03761 HCEG_03761 HCEG_03767 HCEG_03767 HCEG_03787 HCEG_03787 HCEG_03807 HCEG_03807 HCEG_03879 HCEG_03879 HCEG_03939 HCEG_03939 HCEG_03978 HCEG_03978 HCEG_04069 HCEG_04069 HCEG_04085 HCEG_04085 HCEG_04161 HCEG_04161 HCEG_03341 HCEG_03341 HCEG_04169 HCEG_04169 HCEG_04201 HCEG_04201 HCEG_04214 HCEG_04214 HCEG_03411 HCEG_03411 HCEG_04229 HCEG_04229 HCEG_03494 HCEG_03494 HCEG_03572 HCEG_03572 HCEG_04414 HCEG_04414 PIF1 PIF1 HCEG_03632 HCEG_03632 HCEG_04440 HCEG_04440 HCEG_03672 HCEG_03672 HCEG_03676 HCEG_03676 HCEG_03677 HCEG_03677 HCEG_03683 HCEG_03683 HCEG_04483 HCEG_04483 HCEG_04515 HCEG_04515 HCEG_04520 HCEG_04520 HCEG_04526 HCEG_04526 HCEG_04655 HCEG_04655 HCEG_05498 HCEG_05498 HCEG_04708 HCEG_04708 HCEG_05535 HCEG_05535 HCEG_04725 HCEG_04725 HCEG_04728 HCEG_04728 HCEG_04744 HCEG_04744 HCEG_05571 HCEG_05571 UNG1 UNG1 HCEG_05608 HCEG_05608 HCEG_04780 HCEG_04780 HCEG_05620 HCEG_05620 HCEG_04841 HCEG_04841 HCEG_05683 HCEG_05683 HCEG_05707 HCEG_05707 HCEG_05708 HCEG_05708 HCEG_04880 HCEG_04880 HCEG_04892 HCEG_04892 HCEG_04910 HCEG_04910 HCEG_05753 HCEG_05753 HCEG_05761 HCEG_05761 HCEG_05767 HCEG_05767 HCEG_04968 HCEG_04968 HCEG_05855 HCEG_05855 HCEG_05050 HCEG_05050 HCEG_05066 HCEG_05066 HCEG_05105 HCEG_05105 HCEG_05124 HCEG_05124 HCEG_05134 HCEG_05134 HCEG_05170 HCEG_05170 SLX4 SLX4 HCEG_05299 HCEG_05299 HCEG_05307 HCEG_05307 HCEG_05316 HCEG_05316 HCEG_05390 HCEG_05390 HCEG_04585 HCEG_04585 HCEG_04606 HCEG_04606 HCEG_05458 HCEG_05458 HCEG_06375 HCEG_06375 HCEG_06376 HCEG_06376 HCEG_07276 HCEG_07276 HCEG_06459 HCEG_06459 HCEG_07330 HCEG_07330 HCEG_07331 HCEG_07331 HCEG_06508 HCEG_06508 HCEG_06518 HCEG_06518 HCEG_06546 HCEG_06546 HCEG_07366 HCEG_07366 HCEG_06621 HCEG_06621 HCEG_06721 HCEG_06721 HCEG_06763 HCEG_06763 HCEG_06771 HCEG_06771 HCEG_06815 HCEG_06815 HCEG_05980 HCEG_05980 HCEG_05998 HCEG_05998 HCEG_05999 HCEG_05999 HCEG_06054 HCEG_06054 HCEG_06921 HCEG_06921 HCEG_06125 HCEG_06125 HCEG_06937 HCEG_06937 HCEG_06939 HCEG_06939 HCEG_06955 HCEG_06955 HCEG_06145 HCEG_06145 HCEG_07027 HCEG_07027 HCEG_06219 HCEG_06219 HCEG_07035 HCEG_07035 HCEG_07040 HCEG_07040 SLX1 SLX1 HCEG_06342 HCEG_06342 FEN1 FEN1 HCEG_07381 HCEG_07381 HCEG_07470 HCEG_07470 HCEG_07540 HCEG_07540 HCEG_07550 HCEG_07550 HCEG_07586 HCEG_07586 HCEG_07616 HCEG_07616 HCEG_07637 HCEG_07637 HCEG_07774 HCEG_07774 HCEG_07802 HCEG_07802 HCEG_07847 HCEG_07847 HCEG_07865 HCEG_07865 HCEG_07939 HCEG_07939 HCEG_07953 HCEG_07953 HCEG_08056 HCEG_08056 HCEG_08074 HCEG_08074 HCEG_08081 HCEG_08081 HCEG_08122 HCEG_08122 HCEG_08146 HCEG_08146 HCEG_08250 HCEG_08250 HCEG_08255 HCEG_08255 HCEG_08291 HCEG_08291 HCEG_08325 HCEG_08325 HCEG_08337 HCEG_08337 HCEG_08434 HCEG_08434 HCEG_08487 HCEG_08487 HCEG_08488 HCEG_08488 HCEG_08492 HCEG_08492 HCEG_08590 HCEG_08590 HCEG_08618 HCEG_08618 HCEG_08654 HCEG_08654 HCEG_08706 HCEG_08706 HCEG_08731 HCEG_08731 HCEG_08762 HCEG_08762 HCEG_08818 HCEG_08818 HCEG_08829 HCEG_08829 HCEG_08870 HCEG_08870 HCEG_08877 HCEG_08877 HCEG_08962 HCEG_08962 HCEG_08971 HCEG_08971 HCEG_09028 HCEG_09028 HCEG_09083 HCEG_09083 HCEG_09088 HCEG_09088 HCEG_09203 HCEG_09203 HCEG_09236 HCEG_09236 HCEG_09266 HCEG_09266 HCEG_09275 HCEG_09275 HCEG_09380 HCEG_09380 HCEG_09418 HCEG_09418
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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HCEG_06134DNA helicase; Belongs to the MCM family. (718 aa)
HCEG_00503DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1178 aa)
HCEG_01348RSC complex subunit. (577 aa)
HCEG_01365Mating-type switching protein swi10. (361 aa)
HCEG_01397DNA mismatch repair protein. (994 aa)
HCEG_00608Uncharacterized protein. (747 aa)
HCEG_00625Uncharacterized protein. (518 aa)
HCEG_00630BRCT domain-containing protein. (857 aa)
HCEG_01432DNA-3-methyladenine glycosylase. (394 aa)
HCEG_01451RAD52 DNA repair protein RADC. (567 aa)
HCEG_01510DNA methyltransferase. (613 aa)
HCEG_01528Polynucleotide kinase. (476 aa)
HCEG_00693DNA repair protein RAD50. (1298 aa)
HCEG_00694DNA repair protein RAD1. (401 aa)
HCEG_00695Predicted protein. (77 aa)
HCEG_01540Predicted protein. (125 aa)
HCEG_01634DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (941 aa)
HCEG_00807CDK-activating kinase assembly factor MAT1. (379 aa)
HCEG_01679DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2232 aa)
HCEG_00019DNA cross-link repair protein pso2/snm1. (841 aa)
HCEG_00041Serine/threonine protein kinase. (1106 aa)
HCEG_01743Casein kinase I; Belongs to the protein kinase superfamily. (401 aa)
HCEG_00908Rad51 domain-containing protein. (456 aa)
HCEG_00927Rad4 family protein. (907 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (533 aa)
HCEG_01756ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (723 aa)
HCEG_01760DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (130 aa)
HCEG_01761DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (450 aa)
HCEG_01781Acetamidase/formamidase. (324 aa)
HCEG_00155MAGE domain-containing protein. (336 aa)
HCEG_01827DNA repair and recombination protein RAD54. (830 aa)
HCEG_00179Rnapii degradation factor def1. (884 aa)
HCEG_00199Nucleosome binding protein. (102 aa)
HCEG_01097DNA ligase. (945 aa)
HCEG_00319Uncharacterized protein. (180 aa)
HCEG_01115High-affinity nickel transporter. (694 aa)
HCEG_01151DNA directed RNA polymerase II 15 kDa subunit. (126 aa)
HCEG_00465Pms1-prov protein. (903 aa)
HCEG_01304Protein kinase domain-containing protein. (390 aa)
HCEG_01982Zn(2)-C6 fungal-type domain-containing protein. (661 aa)
HCEG_01985ATP-dependent DNA helicase. (1490 aa)
HCEG_02800GRF zinc finger domain-containing protein. (432 aa)
HCEG_02823Uncharacterized protein. (512 aa)
HCEG_02846DNA repair helicase RAD3. (797 aa)
HCEG_0203326S protease regulatory subunit S10B; Belongs to the AAA ATPase family. (392 aa)
HCEG_02058RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (485 aa)
HCEG_02071Serine/threonine protein kinase. (501 aa)
HCEG_02916Crossover junction endonuclease mus81. (650 aa)
HCEG_02964DNA ligase. (844 aa)
HCEG_02181Sir2 family histone deacetylase Hst4. (574 aa)
HCEG_02186Polymerase. (717 aa)
HCEG_02196DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa)
HCEG_02199Predicted protein. (122 aa)
HCEG_03023Uncharacterized protein. (1565 aa)
HCEG_03038Postreplication repair E3 ubiquitin-protein ligase rad18. (420 aa)
HCEG_03053DNA polymerase. (1111 aa)
HCEG_03103Histidine triad nucleotide-binding protein. (281 aa)
HCEG_02297DNA replication helicase Dna2. (1609 aa)
HCEG_02315Ubiquitin-conjugating enzyme. (139 aa)
HCEG_02322Formamidopyrimidine-DNA glycosylase lyase mutM. (383 aa)
HCEG_03144DNA repair protein RAD16. (848 aa)
HCEG_03145DNA repair protein RAD7. (622 aa)
HCEG_02351RNA polymerase II transcription factor. (644 aa)
HCEG_02358DNA replication complex GINS protein psf3. (177 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (818 aa)
HCEG_02404Proteasome activator subunit 4. (250 aa)
HCEG_02405Proteasome activator subunit 4. (2188 aa)
HCEG_03223DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1166 aa)
HCEG_02436DNA polymerase iota. (660 aa)
HCEG_02441DNA replication ATPase. (547 aa)
HCEG_02461RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (459 aa)
HCEG_02467Histone acetylase complex subunit. (331 aa)
HCEG_02477Transcription regulator BDF1. (845 aa)
HCEG_02479PSF1 domain-containing protein. (277 aa)
HCEG_02555DNA mismatch repair protein. (738 aa)
HCEG_02556DNA_MISMATCH_REPAIR_2 domain-containing protein. (216 aa)
HCEG_02649RecA family ATPase Rhp57. (701 aa)
HCEG_02675Cell cycle control protein. (967 aa)
HCEG_01865WD40 repeat-containing protein. (487 aa)
HCEG_02708Cell wall protein. (251 aa)
HCEG_02758Uncharacterized protein. (827 aa)
HCEG_02775DsDNA-dependent ATPase. (974 aa)
HCEG_04557Tyrosyl-DNA phosphodiesterase. (682 aa)
HCEG_03750Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (530 aa)
HCEG_03761DNA ligase. (1023 aa)
HCEG_03767Serine/threonine-protein phosphatase. (467 aa)
HCEG_03787WD40 repeat-containing protein. (1040 aa)
HCEG_03807DNA binding protein. (736 aa)
HCEG_03879MutS2 protein. (999 aa)
HCEG_03939DNA repair/transcription protein. (1045 aa)
HCEG_03978Poly [ADP-ribose] polymerase. (617 aa)
HCEG_04069Pre-mRNA-splicing factor Cwc24. (826 aa)
HCEG_04085Ku70 protein. (655 aa)
HCEG_04161Plus3 domain-containing protein. (638 aa)
HCEG_03341Uncharacterized protein. (306 aa)
HCEG_041696-O-methylguanine DNA methyltransferase. (197 aa)
HCEG_04201Exonuclease. (830 aa)
HCEG_04214DNA repair protein RAD18. (1161 aa)
HCEG_03411DNA replication initiation factor Cdc45. (846 aa)
HCEG_04229Histone H2A; Belongs to the histone H2A family. (134 aa)
HCEG_03494DNA repair protein Dds20/Mei5. (277 aa)
HCEG_03572Telomere length regulator protein. (1231 aa)
HCEG_04414Rad51 family DNA repair protein. (449 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (794 aa)
HCEG_03632Ubiquitin-protein ligase E4. (476 aa)
HCEG_04440RNA polymerase II transcription factor B subunit 5. (120 aa)
HCEG_03672SsDNA binding protein Ssb3. (117 aa)
HCEG_03676Nuclear pore complex subunit Nup192; Belongs to the cullin family. (2530 aa)
HCEG_03677Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2803 aa)
HCEG_03683DNA repair protein RAD5. (1196 aa)
HCEG_04483Mitochondrial genome maintenance protein MGM101. (303 aa)
HCEG_04515DNA repair and recombination protein RAD26. (1092 aa)
HCEG_04520DNA polymerase. (1458 aa)
HCEG_04526DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (450 aa)
HCEG_04655DNA repair protein Nse1. (325 aa)
HCEG_05498Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (914 aa)
HCEG_04708XPG_I_2 domain-containing protein. (728 aa)
HCEG_05535DNA repair protein. (705 aa)
HCEG_04725Phosphatidyl inositol 3-kinase; Belongs to the PI3/PI4-kinase family. (2474 aa)
HCEG_04728Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (344 aa)
HCEG_0474426S protease regulatory subunit 8; Belongs to the AAA ATPase family. (389 aa)
HCEG_05571DNA polymerase epsilon subunit B. (747 aa)
UNG1Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (886 aa)
HCEG_05608Double-strand-break repair protein. (600 aa)
HCEG_04780Topoisomerase 1-associated factor. (1110 aa)
HCEG_05620DNA helicase; Belongs to the MCM family. (1806 aa)
HCEG_04841MYB and HSA domain-containing protein. (1491 aa)
HCEG_05683DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1162 aa)
HCEG_05707PAPA-1 domain-containing protein. (425 aa)
HCEG_05708Uncharacterized protein. (2266 aa)
HCEG_04880Uncharacterized protein. (293 aa)
HCEG_04892NUDIX domain-containing protein. (313 aa)
HCEG_04910Activator 1 41 kDa subunit. (394 aa)
HCEG_05753Uncharacterized protein. (281 aa)
HCEG_05761Activator 1 subunit 5. (352 aa)
HCEG_05767Replication factor C subunit 1. (1071 aa)
HCEG_04968DUF1767 domain-containing protein. (261 aa)
HCEG_05855Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (500 aa)
HCEG_05050Meiotic recombination protein dmc1; Belongs to the RecA family. (381 aa)
HCEG_05066Uncharacterized protein. (425 aa)
HCEG_05105FYVE zinc finger protein. (679 aa)
HCEG_05124Chromatin modification-related protein. (444 aa)
HCEG_05134Uncharacterized protein. (1032 aa)
HCEG_05170C6 zinc finger domain-containing protein. (847 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (843 aa)
HCEG_05299FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (575 aa)
HCEG_053078-oxoguanine DNA glycosylase. (422 aa)
HCEG_05316Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (820 aa)
HCEG_05390Helicase C-terminal domain-containing protein. (1142 aa)
HCEG_04585Uncharacterized protein. (119 aa)
HCEG_04606HD superfamily hydrolase. (383 aa)
HCEG_05458DNA-directed DNA polymerase theta. (934 aa)
HCEG_06375Zn(2)-C6 fungal-type domain-containing protein. (624 aa)
HCEG_06376Uncharacterized protein. (269 aa)
HCEG_07276YEATS family protein. (279 aa)
HCEG_06459Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (472 aa)
HCEG_07330Uncharacterized protein. (376 aa)
HCEG_07331Chromosome segregation protein. (849 aa)
HCEG_06508Ubiquitin homeostasis protein lub1. (788 aa)
HCEG_06518BRCT domain-containing protein. (269 aa)
HCEG_06546Ubiquitin/metalloprotease fusion protein. (344 aa)
HCEG_07366Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (341 aa)
HCEG_06621RNA polymerase II transcription factor B subunit 4. (412 aa)
HCEG_06721DNA helicase; Belongs to the MCM family. (965 aa)
HCEG_06763Sister chromatid cohesion protein. (1772 aa)
HCEG_06771Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (516 aa)
HCEG_06815Mitotic spindle checkpoint protein. (181 aa)
HCEG_05980Double-strand break repair protein; Belongs to the MRE11/RAD32 family. (1016 aa)
HCEG_05998Uncharacterized protein. (111 aa)
HCEG_05999RNA binding domain-containing protein. (162 aa)
HCEG_06054ERCC4 domain-containing protein. (627 aa)
HCEG_06921Single-stranded DNA binding protein p30 subunit. (276 aa)
HCEG_06125ATP-dependent DNA ligase. (1087 aa)
HCEG_06937DNA damage-binding protein 1a. (1201 aa)
HCEG_06939Uncharacterized protein. (100 aa)
HCEG_06955DNA helicase; Belongs to the MCM family. (882 aa)
HCEG_06145Histone acetylase complex subunit Paf400; Belongs to the PI3/PI4-kinase family. (3841 aa)
HCEG_07027DNA polymerase. (1637 aa)
HCEG_06219DNA repair helicase RAD25. (1416 aa)
HCEG_07035Predicted protein. (266 aa)
HCEG_07040Endo/exonuclease/phosphatase domain-containing protein. (636 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (421 aa)
HCEG_06342Meiotic recombination protein spo11. (376 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (359 aa)
HCEG_07381RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (467 aa)
HCEG_07470General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (505 aa)
HCEG_07540Activator 1 37 kDa subunit. (354 aa)
HCEG_07550Serine/threonine protein kinase. (681 aa)
HCEG_07586Tyrosyl-DNA phosphodiesterase domain-containing protein. (652 aa)
HCEG_07616Enhancer of polycomb-like protein. (588 aa)
HCEG_07637Uncharacterized protein. (320 aa)
HCEG_07774Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (1245 aa)
HCEG_07802Uncharacterized protein. (1198 aa)
HCEG_07847Serine/threonine protein kinase. (581 aa)
HCEG_07865DNA polymerase kappa. (604 aa)
HCEG_07939FACT complex subunit spt16. (1023 aa)
HCEG_07953Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (602 aa)
HCEG_08056DNA ATP-dependent helicase. (1676 aa)
HCEG_08074SNF2-family ATP dependent chromatin remodeling factor. (1423 aa)
HCEG_08081Methylated-DNA-protein-cysteine methyltransferase. (479 aa)
HCEG_08122SNF2 family helicase/ATPase. (1787 aa)
HCEG_08146DUF1337 domain-containing protein. (144 aa)
HCEG_08250Fumarate hydratase class II. (567 aa)
HCEG_08255Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (156 aa)
HCEG_08291Serine/threonine protein kinase cds1. (701 aa)
HCEG_08325DNA repair protein RAD1. (975 aa)
HCEG_08337ENDO3c domain-containing protein. (270 aa)
HCEG_08434DNA excision repair protein Rad2. (1159 aa)
HCEG_08487Uncharacterized protein. (204 aa)
HCEG_08488Uncharacterized protein. (166 aa)
HCEG_08492SP-RING-type domain-containing protein. (502 aa)
HCEG_08590Nitrilase. (1056 aa)
HCEG_08618Uncharacterized protein. (1589 aa)
HCEG_08654ATP-dependent helicase RIS1. (1052 aa)
HCEG_08706Oxidoreductase. (420 aa)
HCEG_08731DNA lyase. (528 aa)
HCEG_08762Uncharacterized protein. (653 aa)
HCEG_08818Uncharacterized protein. (238 aa)
HCEG_08829DNA mismatch repair protein. (1515 aa)
HCEG_08870DNA helicase; Belongs to the MCM family. (877 aa)
HCEG_08877Thermotolerance protein. (1294 aa)
HCEG_08962Uracil DNA glycosylase superfamily protein. (371 aa)
HCEG_08971RING-13 protein. (1188 aa)
HCEG_09028Checkpoint protein; Belongs to the HUS1 family. (361 aa)
HCEG_09083Rad21/Rec8 N terminal domain-containing protein. (713 aa)
HCEG_09088SMC_N domain-containing protein. (1160 aa)
HCEG_09203UV-damage endonuclease. (704 aa)
HCEG_09236DNA polymerase delta subunit 4. (214 aa)
HCEG_09266Activator 1 subunit 3. (443 aa)
HCEG_09275DNA repair protein RAD14. (334 aa)
HCEG_09380Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
HCEG_09418BTB domain-containing protein. (649 aa)
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
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