STRINGSTRING
HCEG_04779 HCEG_04779 HCEG_00516 HCEG_00516 HCEG_01475 HCEG_01475 HCEG_00751 HCEG_00751 HCEG_00758 HCEG_00758 HCEG_00805 HCEG_00805 HCEG_00873 HCEG_00873 HCEG_01703 HCEG_01703 HCEG_00068 HCEG_00068 HCEG_00074 HCEG_00074 HCEG_00075 HCEG_00075 HCEG_00090 HCEG_00090 HCEG_01817 HCEG_01817 HCEG_00165 HCEG_00165 HCEG_00388 HCEG_00388 HCEG_02080 HCEG_02080 HCEG_03125 HCEG_03125 HCEG_02370 HCEG_02370 HCEG_02499 HCEG_02499 HCEG_02560 HCEG_02560 HCEG_02773 HCEG_02773 HCEG_03864 HCEG_03864 HCEG_04091 HCEG_04091 HCEG_03348 HCEG_03348 HCEG_04195 HCEG_04195 HCEG_03663 HCEG_03663 HCEG_04628 HCEG_04628 HCEG_04710 HCEG_04710 HCEG_05531 HCEG_05531 HCEG_04797 HCEG_04797 HCEG_04820 HCEG_04820 HCEG_05132 HCEG_05132 HCEG_05140 HCEG_05140 HCEG_06492 HCEG_06492 HCEG_07316 HCEG_07316 HCEG_06590 HCEG_06590 HCEG_06745 HCEG_06745 cprA cprA HCEG_07016 HCEG_07016 HCEG_07513 HCEG_07513 HCEG_07547 HCEG_07547 HCEG_07569 HCEG_07569 HCEG_07868 HCEG_07868 HCEG_08621 HCEG_08621 HCEG_08874 HCEG_08874 HCEG_09279 HCEG_09279 HCEG_09351 HCEG_09351
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCEG_04779Enoyl-CoA hydratase. (158 aa)
HCEG_00516FAD binding domain-containing protein. (499 aa)
HCEG_01475Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (406 aa)
HCEG_00751Enoyl-CoA hydratase. (215 aa)
HCEG_00758C-3 sterol dehydrogenase/C-4 decarboxylase. (380 aa)
HCEG_00805Sterol desaturase; Belongs to the sterol desaturase family. (253 aa)
HCEG_00873Ergosterol biosynthetic protein. (133 aa)
HCEG_01703UDP-glucose:sterol glycosyltransferase. (1468 aa)
HCEG_00068Nonribosomal peptide synthetase. (1955 aa)
HCEG_00074Long-chain-fatty-acid-CoA ligase. (589 aa)
HCEG_00075Acetylase. (439 aa)
HCEG_00090C-3 sterol dehydrogenase/C-4 decarboxylase. (426 aa)
HCEG_01817C-3 sterol dehydrogenase/C-4 decarboxylase. (352 aa)
HCEG_001653-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (376 aa)
HCEG_00388C-14 sterol reductase. (503 aa)
HCEG_02080Uncharacterized protein. (308 aa)
HCEG_03125FAD binding domain-containing protein. (660 aa)
HCEG_023703-ketosteroid reductase. (456 aa)
HCEG_02499C-24(28) sterol reductase. (472 aa)
HCEG_02560Sterol desaturase; Belongs to the sterol desaturase family. (337 aa)
HCEG_02773EXPERA domain-containing protein. (248 aa)
HCEG_038647-dehydrosterol-delta 7-reductase. (459 aa)
HCEG_04091Squalene epoxidase. (484 aa)
HCEG_03348Predicted protein. (151 aa)
HCEG_04195Sucrase/ferredoxin domain-containing protein. (344 aa)
HCEG_03663Enoyl-CoA hydratase. (135 aa)
HCEG_04628Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol. (380 aa)
HCEG_04710C4-methylsterol oxidase; Belongs to the sterol desaturase family. (249 aa)
HCEG_05531NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (321 aa)
HCEG_04797Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (581 aa)
HCEG_04820INSIG domain-containing protein. (440 aa)
HCEG_05132Cytochrome P450 sterol 14 alpha-demethylase; Belongs to the cytochrome P450 family. (515 aa)
HCEG_051403-hydroxy-3-methylglutaryl coenzyme A reductase. (1135 aa)
HCEG_06492AMP dependent synthetase and ligase. (600 aa)
HCEG_07316C-24(28) sterol reductase. (539 aa)
HCEG_06590Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (388 aa)
HCEG_06745Phosphomevalonate kinase; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (542 aa)
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (694 aa)
HCEG_07016C-8 sterol isomerase. (213 aa)
HCEG_07513C-5 sterol desaturase; Belongs to the sterol desaturase family. (356 aa)
HCEG_07547Cytochrome c mitochondrial import factor. (413 aa)
HCEG_07569Sucrose cleavage family protein. (357 aa)
HCEG_07868Squalene synthetase. (472 aa)
HCEG_08621Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (137 aa)
HCEG_08874Cytochrome P450 sterol C-22 desaturase; Belongs to the cytochrome P450 family. (533 aa)
HCEG_09279C-4 methylsterol oxidase; Belongs to the sterol desaturase family. (239 aa)
HCEG_09351Serine/threonine protein kinase chk2; Belongs to the cytochrome P450 family. (1213 aa)
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
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