STRINGSTRING
HCEG_06046 HCEG_06046 HCEG_09296 HCEG_09296 HCEG_09127 HCEG_09127 HCEG_09065 HCEG_09065 HCEG_09058 HCEG_09058 HCEG_08935 HCEG_08935 HCEG_08916 HCEG_08916 HCEG_08863 HCEG_08863 HCEG_08812 HCEG_08812 HCEG_08802 HCEG_08802 HCEG_08482 HCEG_08482 HCEG_08481 HCEG_08481 HCEG_08455 HCEG_08455 HCEG_08439 HCEG_08439 HCEG_08430 HCEG_08430 HCEG_08425 HCEG_08425 HCEG_08359 HCEG_08359 HCEG_08250 HCEG_08250 HCEG_08189 HCEG_08189 HCEG_07958 HCEG_07958 HCEG_07945 HCEG_07945 HCEG_07870 HCEG_07870 HCEG_07817 HCEG_07817 HCEG_07806 HCEG_07806 HCEG_07782 HCEG_07782 HCEG_07652 HCEG_07652 HCEG_07651 HCEG_07651 HCEG_07553 HCEG_07553 HCEG_07389 HCEG_07389 HCEG_06336 HCEG_06336 HCEG_07108 HCEG_07108 HCEG_06279 HCEG_06279 HCEG_06225 HCEG_06225 HCEG_06977 HCEG_06977 PSD2 PSD2 HCEG_06946 HCEG_06946 HCEG_06930 HCEG_06930 HCEG_06082 HCEG_06082 HCEG_06076 HCEG_06076 HCEG_06859 HCEG_06859 HCEG_06009 HCEG_06009 HCEG_05974 HCEG_05974 HCEG_06711 HCEG_06711 HCEG_06691 HCEG_06691 HCEG_06686 HCEG_06686 HCEG_06566 HCEG_06566 HCEG_06561 HCEG_06561 HCEG_06517 HCEG_06517 HCEG_07299 HCEG_07299 HCEG_06470 HCEG_06470 HCEG_06463 HCEG_06463 HCEG_07257 HCEG_07257 HCEG_07219 HCEG_07219 HCEG_05307 HCEG_05307 HCEG_05301 HCEG_05301 HCEG_05242 HCEG_05242 HCEG_05173 HCEG_05173 HCEG_05170 HCEG_05170 HCEG_05944 HCEG_05944 HCEG_05131 HCEG_05131 HCEG_05100 HCEG_05100 HCEG_05921 HCEG_05921 HCEG_05918 HCEG_05918 HCEG_05883 HCEG_05883 HCEG_05875 HCEG_05875 HCEG_05024 HCEG_05024 HCEG_04941 HCEG_04941 HCEG_05753 HCEG_05753 HCEG_05744 HCEG_05744 HCEG_05737 HCEG_05737 HCEG_05690 HCEG_05690 HCEG_05689 HCEG_05689 HCEG_05685 HCEG_05685 HCEG_04828 HCEG_04828 HCEG_05666 HCEG_05666 HCEG_05622 HCEG_05622 HCEG_04809 HCEG_04809 HCEG_04795 HCEG_04795 HCEG_04779 HCEG_04779 HCEG_04756 HCEG_04756 HCEG_04754 HCEG_04754 HCEG_05477 HCEG_05477 HCEG_04641 HCEG_04641 HCEG_03663 HCEG_03663 HCEG_04459 HCEG_04459 HCEG_04415 HCEG_04415 HCEG_04411 HCEG_04411 HCEG_04287 HCEG_04287 HCEG_04286 HCEG_04286 HCEG_04232 HCEG_04232 PSD1 PSD1 HCEG_03382 HCEG_03382 HCEG_03356 HCEG_03356 HCEG_04149 HCEG_04149 HCEG_04136 HCEG_04136 HCEG_03309 HCEG_03309 HCEG_04086 HCEG_04086 HCEG_04008 HCEG_04008 HCEG_03925 HCEG_03925 USB1 USB1 HCEG_03828 HCEG_03828 HCEG_03819 HCEG_03819 HCEG_03759 HCEG_03759 HCEG_03705 HCEG_03705 HCEG_03695 HCEG_03695 HCEG_01954 HCEG_01954 HCEG_01950 HCEG_01950 HCEG_01934 HCEG_01934 HCEG_01929 HCEG_01929 HCEG_02647 HCEG_02647 HCEG_02545 HCEG_02545 HCEG_02511 HCEG_02511 HCEG_02509 HCEG_02509 HCEG_02417 HCEG_02417 HCEG_02408 HCEG_02408 HCEG_02381 HCEG_02381 HCEG_03191 HCEG_03191 HCEG_02322 HCEG_02322 HCEG_02282 HCEG_02282 cyn1 cyn1 HCEG_03021 HCEG_03021 HCEG_02215 HCEG_02215 HCEG_02983 HCEG_02983 HCEG_02965 HCEG_02965 HCEG_02962 HCEG_02962 HCEG_02938 HCEG_02938 HCEG_02864 HCEG_02864 HCEG_02034 HCEG_02034 HCEG_00468 HCEG_00468 HCEG_00453 HCEG_00453 HCEG_01258 HCEG_01258 HCEG_01170 HCEG_01170 HCEG_01169 HCEG_01169 HCEG_01145 HCEG_01145 HCEG_01115 HCEG_01115 HCEG_00250 HCEG_00250 HCEG_00243 HCEG_00243 HCEG_00212 HCEG_00212 HCEG_00188 HCEG_00188 HCEG_01823 HCEG_01823 HCEG_00986 HCEG_00986 HCEG_00964 HCEG_00964 HCEG_00135 HCEG_00135 NTH1 NTH1 HCEG_00905 HCEG_00905 HCEG_00106 HCEG_00106 HCEG_00072 HCEG_00072 HCEG_00843 HCEG_00843 hxB hxB HCEG_00751 HCEG_00751 HCEG_01556 HCEG_01556 HCEG_01536 HCEG_01536 MDE1 MDE1 HCEG_00660 HCEG_00660 HCEG_01475 HCEG_01475 HCEG_01474 HCEG_01474 HCEG_00634 HCEG_00634 HCEG_00594 HCEG_00594 HCEG_00578 HCEG_00578 HCEG_00560 HCEG_00560 HCEG_00515 HCEG_00515 HCEG_00490 HCEG_00490
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCEG_06046Uncharacterized protein. (171 aa)
HCEG_09296Fumarylacetoacetate hydrolase. (289 aa)
HCEG_09127Glutamate decarboxylase; Belongs to the group II decarboxylase family. (569 aa)
HCEG_09065Isocitrate lyase. (600 aa)
HCEG_090582-methylcitrate dehydratase. (557 aa)
HCEG_089353,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (235 aa)
HCEG_08916Anthranilate synthase component I. (518 aa)
HCEG_08863Acetolactate synthase; Belongs to the TPP enzyme family. (603 aa)
HCEG_08812Aminotransferase. (573 aa)
HCEG_08802Tryptophan synthase. (723 aa)
HCEG_08482Phosphoenolpyruvate carboxykinase AcuF. (473 aa)
HCEG_08481Uncharacterized protein. (217 aa)
HCEG_08455Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (309 aa)
HCEG_08439Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (479 aa)
HCEG_08430Citrate lyase subunit beta-like protein. (321 aa)
HCEG_08425ZIP Zinc transporter. (642 aa)
HCEG_083593-hydroxyisobutyrate dehydrogenase. (444 aa)
HCEG_08250Fumarate hydratase class II. (567 aa)
HCEG_08189Threonine aldolase. (374 aa)
HCEG_07958Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (378 aa)
HCEG_07945Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (549 aa)
HCEG_07870Uncharacterized protein. (66 aa)
HCEG_07817Cystathionine beta-lyase MetG. (447 aa)
HCEG_07806Acetoacetyl-CoA reductase. (901 aa)
HCEG_07782Enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (293 aa)
HCEG_07652Folic acid synthesis protein. (494 aa)
HCEG_07651Cysteine desulfurase. (543 aa)
HCEG_07553Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (797 aa)
HCEG_07389DUF4396 domain-containing protein. (173 aa)
HCEG_06336tRNA-splicing endonuclease subunit SEN2. (497 aa)
HCEG_07108Deoxyribose-phosphate aldolase. (277 aa)
HCEG_06279S-adenosylmethionine decarboxylase proenzyme. (551 aa)
HCEG_06225ThiJ/PfpI family protein. (245 aa)
HCEG_06977Von Willebrand domain-containing protein. (1069 aa)
PSD2Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (1063 aa)
HCEG_06946Amidase. (623 aa)
HCEG_06930Uncharacterized protein. (69 aa)
HCEG_06082Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (306 aa)
HCEG_06076Uncharacterized protein. (152 aa)
HCEG_06859Pkinase_fungal domain-containing protein. (700 aa)
HCEG_06009Enoyl-CoA hydratase. (244 aa)
HCEG_05974Flavodoxin and radical SAM domain-containing protein. (809 aa)
HCEG_06711Uncharacterized protein. (419 aa)
HCEG_06691APH domain-containing protein. (301 aa)
HCEG_06686tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...] (310 aa)
HCEG_06566Uncharacterized protein. (776 aa)
HCEG_06561Threonine synthase. (536 aa)
HCEG_06517Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (770 aa)
HCEG_07299DNA repair protein RAD26. (809 aa)
HCEG_06470Pkinase_fungal domain-containing protein. (110 aa)
HCEG_06463Ubiquitin-protein ligase molybdopterin-converting factor. (605 aa)
HCEG_07257Alpha-1,2 mannosyltransferase. (487 aa)
HCEG_07219Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (243 aa)
HCEG_053078-oxoguanine DNA glycosylase. (422 aa)
HCEG_05301Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (222 aa)
HCEG_05242Dihydroxy acid dehydratase. (610 aa)
HCEG_05173Threonine aldolase. (408 aa)
HCEG_05170C6 zinc finger domain-containing protein. (847 aa)
HCEG_05944Dihydroxy acid dehydratase. (611 aa)
HCEG_05131Uncharacterized protein. (307 aa)
HCEG_05100Cystathionine gamma-synthase. (402 aa)
HCEG_05921Siroheme biosynthesis protein MET8. (260 aa)
HCEG_05918DUF5353 domain-containing protein. (194 aa)
HCEG_05883Uncharacterized protein. (650 aa)
HCEG_05875Glutathione-dependent formaldehyde-activating protein. (149 aa)
HCEG_05024HET domain-containing protein. (619 aa)
HCEG_04941Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (227 aa)
HCEG_05753Uncharacterized protein. (281 aa)
HCEG_05744Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (575 aa)
HCEG_05737Hydroxymethylglutaryl-CoA lyase. (355 aa)
HCEG_05690Adenylate cyclase. (1046 aa)
HCEG_05689Adenylate cyclase. (781 aa)
HCEG_05685DJ-1/PfpI family protein. (227 aa)
HCEG_04828Phosphotransferase enzyme family protein. (247 aa)
HCEG_05666Pyridoxal-dependent decarboxylase. (444 aa)
HCEG_05622IdgA domain-containing protein. (809 aa)
HCEG_04809Predicted protein. (345 aa)
HCEG_04795L-serine dehydratase. (502 aa)
HCEG_04779Enoyl-CoA hydratase. (158 aa)
HCEG_04756Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (338 aa)
HCEG_04754Uncharacterized protein. (348 aa)
HCEG_05477Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (323 aa)
HCEG_04641Aromatic-L-amino acid decarboxylase. (539 aa)
HCEG_03663Enoyl-CoA hydratase. (135 aa)
HCEG_04459Glutamate decarboxylase; Belongs to the group II decarboxylase family. (516 aa)
HCEG_04415Serine racemase. (404 aa)
HCEG_04411Uncharacterized protein. (322 aa)
HCEG_04287MaoC-like domain-containing protein. (393 aa)
HCEG_04286Chorismate mutase/prephenate dehydratase. (345 aa)
HCEG_04232Uncharacterized protein. (299 aa)
PSD1Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (546 aa)
HCEG_03382Orotidine-5'-phosphate decarboxylase. (482 aa)
HCEG_03356Enoyl-CoA hydratase/isomerase. (316 aa)
HCEG_04149Pkinase_fungal domain-containing protein. (141 aa)
HCEG_04136Pyridoxine biosynthesis protein pyroA; Belongs to the PdxS/SNZ family. (320 aa)
HCEG_03309Molybdopterin cofactor biosynthetic protein. (769 aa)
HCEG_04086Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (427 aa)
HCEG_04008Phosphotransferase enzyme family protein. (299 aa)
HCEG_03925Peroxisomal targeting signal-1 receptor. (1286 aa)
USB1U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (330 aa)
HCEG_03828Cystathionine gamma-lyase. (425 aa)
HCEG_03819ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (386 aa)
HCEG_03759C6 zinc finger domain-containing protein. (642 aa)
HCEG_03705Uracil-5-carboxylate decarboxylase; Belongs to the metallo-dependent hydrolases superfamily. (285 aa)
HCEG_03695Pyruvate decarboxylase dehydrogenase E1 component alpha subunit. (592 aa)
HCEG_01954Uncharacterized protein. (323 aa)
HCEG_01950F-box domain-containing protein. (846 aa)
HCEG_01934Argininosuccinate lyase. (471 aa)
HCEG_01929Uncharacterized protein. (410 aa)
HCEG_02647Predicted protein. (100 aa)
HCEG_02545Urea hydro-lyase/cyanamide hydratase. (254 aa)
HCEG_02511D-ser_dehydrat domain-containing protein. (465 aa)
HCEG_02509Dihydrodipicolinate synthetase; Belongs to the DapA family. (331 aa)
HCEG_02417DlpA domain-containing protein. (242 aa)
HCEG_02408Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (228 aa)
HCEG_02381Uncharacterized protein. (204 aa)
HCEG_031913-dehydroshikimate dehydratase. (405 aa)
HCEG_02322Formamidopyrimidine-DNA glycosylase lyase mutM. (383 aa)
HCEG_02282DUF636 domain-containing protein. (163 aa)
cyn1Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (163 aa)
HCEG_03021Scytalone dehydratase. (162 aa)
HCEG_02215TIM-barrel enzyme family protein. (298 aa)
HCEG_02983Ribonuclease T2-like protein; Belongs to the RNase T2 family. (433 aa)
HCEG_02965Macrophage binding protein. (244 aa)
HCEG_02962Glutamate decarboxylase. (566 aa)
HCEG_02938Phosphoketolase. (801 aa)
HCEG_028643-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1574 aa)
HCEG_02034Enolase. (438 aa)
HCEG_00468Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (446 aa)
HCEG_00453Uncharacterized protein. (161 aa)
HCEG_01258Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (534 aa)
HCEG_01170Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (287 aa)
HCEG_01169Glutathione-s-transferase. (157 aa)
HCEG_01145Glutamine amidotransferase subunit pdxT. (279 aa)
HCEG_01115High-affinity nickel transporter. (694 aa)
HCEG_00250Peroxisomal dehydratase. (308 aa)
HCEG_00243CAIB/BAIF family enzyme. (451 aa)
HCEG_00212Enoyl-CoA hydratase/isomerase. (304 aa)
HCEG_00188Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
HCEG_01823Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (778 aa)
HCEG_00986Dihydrodipicolinate synthetase; Belongs to the DapA family. (313 aa)
HCEG_00964L-allo-threonine aldolase. (414 aa)
HCEG_00135Pyruvate decarboxylase. (546 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (533 aa)
HCEG_00905APH domain-containing protein. (334 aa)
HCEG_00106Predicted protein. (140 aa)
HCEG_00072Peroxisomal dehydratase. (322 aa)
HCEG_008433-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (773 aa)
hxBMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (861 aa)
HCEG_00751Enoyl-CoA hydratase. (215 aa)
HCEG_01556Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (868 aa)
HCEG_01536Chorismate synthase. (407 aa)
MDE1Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (240 aa)
HCEG_00660Sphingosine-1-phosphate lyase. (573 aa)
HCEG_01475Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (406 aa)
HCEG_01474Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (307 aa)
HCEG_00634ThiJ/PfpI family protein. (232 aa)
HCEG_00594Dihydrodipicolinate synthetase. (63 aa)
HCEG_00578Isocitrate lyase. (537 aa)
HCEG_00560Uncharacterized protein. (255 aa)
HCEG_00515PEP phosphonomutase. (263 aa)
HCEG_00490Threonine dehydratase. (562 aa)
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
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