(7 nodes) HOPS complex network (Histoplasma capsulatum H88)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCEG_02980	Vacuolar assembly protein. (1283 aa)
	HCEG_03619	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (830 aa)
	HCEG_05905	Vacuolar morphogenesis protein AvaB. (1071 aa)
	HCEG_05286	Vacuolar sorting protein; Belongs to the STXBP/unc-18/SEC1 family. (663 aa)
	HCEG_06059	E3 ubiquitin-protein ligase PEP5. (948 aa)
	HCEG_08103	Vacuolar sorting-associated protein. (973 aa)
	HCEG_09086	Uncharacterized protein. (344 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_02980	HCEG_03619	F0UAV8	F0UH05	Vacuolar assembly protein.	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	0.996
HCEG_02980	HCEG_05286	F0UAV8	F0UKW7	Vacuolar assembly protein.	Vacuolar sorting protein; Belongs to the STXBP/unc-18/SEC1 family.	0.997
HCEG_02980	HCEG_05905	F0UAV8	F0UK55	Vacuolar assembly protein.	Vacuolar morphogenesis protein AvaB.	0.997
HCEG_02980	HCEG_06059	F0UAV8	F0UNT2	Vacuolar assembly protein.	E3 ubiquitin-protein ligase PEP5.	0.997
HCEG_02980	HCEG_08103	F0UAV8	F0USL1	Vacuolar assembly protein.	Vacuolar sorting-associated protein.	0.997
HCEG_02980	HCEG_09086	F0UAV8	F0UVE4	Vacuolar assembly protein.	Uncharacterized protein.	0.970
HCEG_03619	HCEG_02980	F0UH05	F0UAV8	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Vacuolar assembly protein.	0.996
HCEG_03619	HCEG_05286	F0UH05	F0UKW7	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Vacuolar sorting protein; Belongs to the STXBP/unc-18/SEC1 family.	0.996
HCEG_03619	HCEG_05905	F0UH05	F0UK55	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Vacuolar morphogenesis protein AvaB.	0.993
HCEG_03619	HCEG_06059	F0UH05	F0UNT2	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	E3 ubiquitin-protein ligase PEP5.	0.991
HCEG_03619	HCEG_08103	F0UH05	F0USL1	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	Vacuolar sorting-associated protein.	0.996
HCEG_05286	HCEG_02980	F0UKW7	F0UAV8	Vacuolar sorting protein; Belongs to the STXBP/unc-18/SEC1 family.	Vacuolar assembly protein.	0.997
HCEG_05286	HCEG_03619	F0UKW7	F0UH05	Vacuolar sorting protein; Belongs to the STXBP/unc-18/SEC1 family.	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	0.996
HCEG_05286	HCEG_05905	F0UKW7	F0UK55	Vacuolar sorting protein; Belongs to the STXBP/unc-18/SEC1 family.	Vacuolar morphogenesis protein AvaB.	0.997
HCEG_05286	HCEG_06059	F0UKW7	F0UNT2	Vacuolar sorting protein; Belongs to the STXBP/unc-18/SEC1 family.	E3 ubiquitin-protein ligase PEP5.	0.997
HCEG_05286	HCEG_08103	F0UKW7	F0USL1	Vacuolar sorting protein; Belongs to the STXBP/unc-18/SEC1 family.	Vacuolar sorting-associated protein.	0.997
HCEG_05286	HCEG_09086	F0UKW7	F0UVE4	Vacuolar sorting protein; Belongs to the STXBP/unc-18/SEC1 family.	Uncharacterized protein.	0.975
HCEG_05905	HCEG_02980	F0UK55	F0UAV8	Vacuolar morphogenesis protein AvaB.	Vacuolar assembly protein.	0.997
HCEG_05905	HCEG_03619	F0UK55	F0UH05	Vacuolar morphogenesis protein AvaB.	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	0.993
HCEG_05905	HCEG_05286	F0UK55	F0UKW7	Vacuolar morphogenesis protein AvaB.	Vacuolar sorting protein; Belongs to the STXBP/unc-18/SEC1 family.	0.997