(32 nodes) Ubiquitin-like protein binding network (Histoplasma capsulatum H88)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCEG_03856	Cytoskeleton assembly control protein Sla1. (1124 aa)
	HCEG_01567	VHS domain-containing protein. (646 aa)
	HCEG_02104	ZZ type zinc finger domain-containing protein. (846 aa)
	HCEG_02998	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (236 aa)
	HCEG_03180	UBX domain-containing protein Ubx2. (581 aa)
	HCEG_02562	RPN13_C domain-containing protein. (401 aa)
	HCEG_01897	AMFR protein. (197 aa)
	HCEG_01903	NOT2 family protein. (533 aa)
	HCEG_03729	Uncharacterized protein. (560 aa)
	HCEG_03787	WD40 repeat-containing protein. (1040 aa)
	HCEG_04069	Pre-mRNA-splicing factor Cwc24. (826 aa)
	HCEG_04186	CUE domain-containing protein. (719 aa)
	HCEG_03436	GAT domain-containing protein. (558 aa)
	HCEG_03448	UBX domain-containing protein. (524 aa)
	HCEG_04976	STAM-binding protein. (524 aa)
	HCEG_05802	Sulfur metabolite repression control protein. (701 aa)
	HCEG_05382	Endoplasmic reticulum and nuclear membrane protein. (658 aa)
	HCEG_06349	UBA/TS-N domain-containing protein. (885 aa)
	HCEG_06508	Ubiquitin homeostasis protein lub1. (788 aa)
	HCEG_06567	Vacuolar sorting-associated protein. (790 aa)
	HCEG_06575	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (113 aa)
	HCEG_07829	Multidrug transporter. (808 aa)
	HCEG_07017	ESCRT-I component. (590 aa)
	HCEG_06275	UBX domain-containing protein. (387 aa)
	HCEG_07383	Ubiquitin fusion degradation protein. (444 aa)
	HCEG_09228	Spindle assembly checkpoint protein SLDB. (374 aa)
	HCEG_08629	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane. (755 aa)
	HCEG_08510	Uncharacterized protein. (505 aa)
	HCEG_08461	Class E vacuolar protein-sorting machinery protein hse1. (604 aa)
	HCEG_08441	Smr domain-containing protein. (557 aa)
	HCEG_08026	CUE domain-containing protein. (428 aa)
	HCEG_07994	Poly(A)+ RNA export protein. (362 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_01567	HCEG_06567	F0U5X0	F0UMN5	VHS domain-containing protein.	Vacuolar sorting-associated protein.	0.429
HCEG_01567	HCEG_08629	F0U5X0	F0UU37	VHS domain-containing protein.	Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.	0.466
HCEG_02104	HCEG_04069	F0UAH0	F0UEZ7	ZZ type zinc finger domain-containing protein.	Pre-mRNA-splicing factor Cwc24.	0.984
HCEG_02104	HCEG_07017	F0UAH0	F0UPK3	ZZ type zinc finger domain-containing protein.	ESCRT-I component.	0.426
HCEG_02562	HCEG_04069	F0UCS1	F0UEZ7	RPN13_C domain-containing protein.	Pre-mRNA-splicing factor Cwc24.	0.820
HCEG_02562	HCEG_04976	F0UCS1	F0UJG5	RPN13_C domain-containing protein.	STAM-binding protein.	0.874
HCEG_02562	HCEG_06567	F0UCS1	F0UMN5	RPN13_C domain-containing protein.	Vacuolar sorting-associated protein.	0.451
HCEG_02562	HCEG_08026	F0UCS1	F0USD4	RPN13_C domain-containing protein.	CUE domain-containing protein.	0.451
HCEG_02998	HCEG_03180	F0UAX6	F0UC19	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	UBX domain-containing protein Ubx2.	0.647
HCEG_02998	HCEG_04069	F0UAX6	F0UEZ7	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	Pre-mRNA-splicing factor Cwc24.	0.761
HCEG_02998	HCEG_04976	F0UAX6	F0UJG5	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	STAM-binding protein.	0.630
HCEG_02998	HCEG_05802	F0UAX6	F0UJJ6	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	Sulfur metabolite repression control protein.	0.633
HCEG_03180	HCEG_02998	F0UC19	F0UAX6	UBX domain-containing protein Ubx2.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.647
HCEG_03180	HCEG_03448	F0UC19	F0UG27	UBX domain-containing protein Ubx2.	UBX domain-containing protein.	0.909
HCEG_03180	HCEG_03729	F0UC19	F0UDU1	UBX domain-containing protein Ubx2.	Uncharacterized protein.	0.414
HCEG_03180	HCEG_04069	F0UC19	F0UEZ7	UBX domain-containing protein Ubx2.	Pre-mRNA-splicing factor Cwc24.	0.740
HCEG_03180	HCEG_04976	F0UC19	F0UJG5	UBX domain-containing protein Ubx2.	STAM-binding protein.	0.598
HCEG_03180	HCEG_05382	F0UC19	F0UL63	UBX domain-containing protein Ubx2.	Endoplasmic reticulum and nuclear membrane protein.	0.998
HCEG_03180	HCEG_06275	F0UC19	F0UQ10	UBX domain-containing protein Ubx2.	UBX domain-containing protein.	0.950
HCEG_03180	HCEG_06508	F0UC19	F0UME9	UBX domain-containing protein Ubx2.	Ubiquitin homeostasis protein lub1.	0.578