(25 nodes) Cellular response to topologically incorrect protein network (Histoplasma capsulatum H88)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCEG_02198	Mitochondrial outer membrane protein iml2. (752 aa)
	HCEG_02074	Zinc finger protein. (354 aa)
	HCEG_01710	UDP-glucose:glycoprotein glucosyltransferase. (1631 aa)
	HCEG_00022	Protein kinase domain-containing protein. (275 aa)
	HCEG_01576	Golgi phosphoprotein 3 domain-containing protein. (359 aa)
	HCEG_01505	ER associated DnaJ chaperone. (352 aa)
	HCEG_01481	Nuclear envelope protein; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins. (312 aa)
	HCEG_08404	Serine/threonine protein kinase. (1157 aa)
	HCEG_08624	DnaK-type molecular chaperone bipA; Belongs to the heat shock protein 70 family. (676 aa)
	HCEG_03566	Cell division control protein; Belongs to the AAA ATPase family. (771 aa)
	HCEG_04359	Sulfate transporter. (453 aa)
	HCEG_09143	AN1 zinc finger protein. (73 aa)
	HCEG_06357	Clock controlled protein. (503 aa)
	HCEG_06386	Bax inhibitor family protein; Belongs to the BI1 family. (276 aa)
	HCEG_07383	Ubiquitin fusion degradation protein. (444 aa)
	HCEG_04288	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (257 aa)
	HCEG_07668	Uncharacterized protein; Belongs to the heat shock protein 70 family. (675 aa)
	HCEG_03368	Ubiquitin carboxyl-terminal hydrolase. (332 aa)
	HCEG_04750	Ubiquitin fusion degradation protein. (743 aa)
	HCEG_04121	Ankyrin repeat protein. (664 aa)
	HCEG_04836	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (456 aa)
	HCEG_03854	PRKCSH domain-containing protein. (515 aa)
	HCEG_04540	U-box domain-containing protein. (284 aa)
	HCEG_02776	Uncharacterized protein; Belongs to the ClpA/ClpB family. (925 aa)
	HCEG_03241	Calcium/calmodulin dependent protein kinase. (163 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_00022	HCEG_03854	F0U6M1	F0UEA9	Protein kinase domain-containing protein.	PRKCSH domain-containing protein.	0.422
HCEG_00022	HCEG_04540	F0U6M1	F0UDW4	Protein kinase domain-containing protein.	U-box domain-containing protein.	0.608
HCEG_00022	HCEG_08624	F0U6M1	F0UU32	Protein kinase domain-containing protein.	DnaK-type molecular chaperone bipA; Belongs to the heat shock protein 70 family.	0.922
HCEG_00022	HCEG_09143	F0U6M1	F0UVK1	Protein kinase domain-containing protein.	AN1 zinc finger protein.	0.485
HCEG_01505	HCEG_02776	F0U5K6	F0UDN0	ER associated DnaJ chaperone.	Uncharacterized protein; Belongs to the ClpA/ClpB family.	0.611
HCEG_01505	HCEG_04836	F0U5K6	F0UIR8	ER associated DnaJ chaperone.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.404
HCEG_01505	HCEG_07668	F0U5K6	F0URC6	ER associated DnaJ chaperone.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.813
HCEG_01505	HCEG_08624	F0U5K6	F0UU32	ER associated DnaJ chaperone.	DnaK-type molecular chaperone bipA; Belongs to the heat shock protein 70 family.	0.829
HCEG_01710	HCEG_03854	F0U6X7	F0UEA9	UDP-glucose:glycoprotein glucosyltransferase.	PRKCSH domain-containing protein.	0.621
HCEG_01710	HCEG_08624	F0U6X7	F0UU32	UDP-glucose:glycoprotein glucosyltransferase.	DnaK-type molecular chaperone bipA; Belongs to the heat shock protein 70 family.	0.454
HCEG_02074	HCEG_03566	F0UAE0	F0UGQ1	Zinc finger protein.	Cell division control protein; Belongs to the AAA ATPase family.	0.993
HCEG_02074	HCEG_04750	F0UAE0	F0UI79	Zinc finger protein.	Ubiquitin fusion degradation protein.	0.925
HCEG_02074	HCEG_07383	F0UAE0	F0UQJ1	Zinc finger protein.	Ubiquitin fusion degradation protein.	0.973
HCEG_02074	HCEG_09143	F0UAE0	F0UVK1	Zinc finger protein.	AN1 zinc finger protein.	0.790
HCEG_02776	HCEG_01505	F0UDN0	F0U5K6	Uncharacterized protein; Belongs to the ClpA/ClpB family.	ER associated DnaJ chaperone.	0.611
HCEG_02776	HCEG_04836	F0UDN0	F0UIR8	Uncharacterized protein; Belongs to the ClpA/ClpB family.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.625
HCEG_02776	HCEG_07668	F0UDN0	F0URC6	Uncharacterized protein; Belongs to the ClpA/ClpB family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.803
HCEG_02776	HCEG_08624	F0UDN0	F0UU32	Uncharacterized protein; Belongs to the ClpA/ClpB family.	DnaK-type molecular chaperone bipA; Belongs to the heat shock protein 70 family.	0.746
HCEG_03241	HCEG_03854	F0UCD3	F0UEA9	Calcium/calmodulin dependent protein kinase.	PRKCSH domain-containing protein.	0.422
HCEG_03241	HCEG_04540	F0UCD3	F0UDW4	Calcium/calmodulin dependent protein kinase.	U-box domain-containing protein.	0.608