(31 nodes) Protein transmembrane import into intracellular organelle network (Histoplasma capsulatum H88)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCEG_07755	Metallo-beta-lactamase. (344 aa)
	HCEG_07735	Mitochondrial import inner membrane translocase subunit tim16. (215 aa)
	HCEG_07654	Inner membrane translocase subunit tim21. (240 aa)
	HCEG_07522	Mitochondrial import receptor subunit TOM40. (352 aa)
	HCEG_07404	ATP-dependent Clp protease ATP-binding subunit clpX. (621 aa)
	HCEG_06088	CHY-type domain-containing protein. (477 aa)
	HCEG_05983	Mitochondrial import receptor subunit tom-20. (175 aa)
	HCEG_07196	Mitochondrial import receptor subunit tom22. (159 aa)
	HCEG_05246	Peroxisomal biogenesis factor 2. (479 aa)
	HCEG_05174	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (554 aa)
	HCEG_05948	Mitochondrial import inner membrane translocase subunit tim23. (213 aa)
	HCEG_04995	Sulfhydryl oxidase. (221 aa)
	HCEG_05769	Intermembrane space import and assembly protein. (294 aa)
	HCEG_05698	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (252 aa)
	HCEG_04433	S import receptor. (631 aa)
	HCEG_04141	Protein transporter SEC61 alpha subunit. (479 aa)
	HCEG_03923	Peroxin 13. (462 aa)
	HCEG_03801	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (928 aa)
	HCEG_02799	Peroxin 7. (358 aa)
	HCEG_03214	Peroxin 1. (1218 aa)
	HCEG_03197	Peroxin 10. (217 aa)
	HCEG_02259	Mitochondrial inner membrane translocase subunit TIM44. (541 aa)
	HCEG_03034	Peroxin 12. (516 aa)
	HCEG_00280	Peroxin 14. (363 aa)
	HCEG_01777	NADH-ubiquinone oxidoreductase. (196 aa)
	HCEG_00947	Ubiquitin-conjugating enzyme. (174 aa)
	HCEG_01731	Mitochondrial genome maintenance protein Mgr2. (114 aa)
	HCEG_00589	Mitochondrial import inner membrane translocase subunit tim14. (104 aa)
	HCEG_08746	DNL zinc finger domain-containing protein. (219 aa)
	HCEG_08684	Mitochondrial import inner membrane translocase subunit tim17. (160 aa)
	HCEG_07867	DnaJ domain-containing protein. (481 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_00280	HCEG_00947	F0U8L3	F0U7B1	Peroxin 14.	Ubiquitin-conjugating enzyme.	0.834
HCEG_00280	HCEG_02799	F0U8L3	F0UDQ3	Peroxin 14.	Peroxin 7.	0.988
HCEG_00280	HCEG_03034	F0U8L3	F0UB65	Peroxin 14.	Peroxin 12.	0.968
HCEG_00280	HCEG_03197	F0U8L3	F0UC36	Peroxin 14.	Peroxin 10.	0.959
HCEG_00280	HCEG_03214	F0U8L3	F0UC53	Peroxin 14.	Peroxin 1.	0.902
HCEG_00280	HCEG_03801	F0U8L3	F0UE56	Peroxin 14.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	0.662
HCEG_00280	HCEG_03923	F0U8L3	F0UEH8	Peroxin 14.	Peroxin 13.	0.999
HCEG_00589	HCEG_01731	F0U526	F0U6Z8	Mitochondrial import inner membrane translocase subunit tim14.	Mitochondrial genome maintenance protein Mgr2.	0.515
HCEG_00589	HCEG_01777	F0U526	F0U7E8	Mitochondrial import inner membrane translocase subunit tim14.	NADH-ubiquinone oxidoreductase.	0.833
HCEG_00589	HCEG_02259	F0U526	F0UBD5	Mitochondrial import inner membrane translocase subunit tim14.	Mitochondrial inner membrane translocase subunit TIM44.	0.955
HCEG_00589	HCEG_04433	F0U526	F0UH31	Mitochondrial import inner membrane translocase subunit tim14.	S import receptor.	0.473
HCEG_00589	HCEG_05174	F0U526	F0UKK5	Mitochondrial import inner membrane translocase subunit tim14.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.842
HCEG_00589	HCEG_05698	F0U526	F0UIY6	Mitochondrial import inner membrane translocase subunit tim14.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.873
HCEG_00589	HCEG_05769	F0U526	F0UJA9	Mitochondrial import inner membrane translocase subunit tim14.	Intermembrane space import and assembly protein.	0.516
HCEG_00589	HCEG_05948	F0U526	F0UKF2	Mitochondrial import inner membrane translocase subunit tim14.	Mitochondrial import inner membrane translocase subunit tim23.	0.975
HCEG_00589	HCEG_05983	F0U526	F0UNF3	Mitochondrial import inner membrane translocase subunit tim14.	Mitochondrial import receptor subunit tom-20.	0.469
HCEG_00589	HCEG_07196	F0U526	F0ULN3	Mitochondrial import inner membrane translocase subunit tim14.	Mitochondrial import receptor subunit tom22.	0.740
HCEG_00589	HCEG_07522	F0U526	F0UQY0	Mitochondrial import inner membrane translocase subunit tim14.	Mitochondrial import receptor subunit TOM40.	0.595
HCEG_00589	HCEG_07654	F0U526	F0URB2	Mitochondrial import inner membrane translocase subunit tim14.	Inner membrane translocase subunit tim21.	0.848
HCEG_00589	HCEG_07735	F0U526	F0URJ3	Mitochondrial import inner membrane translocase subunit tim14.	Mitochondrial import inner membrane translocase subunit tim16.	0.990