STRINGSTRING
HCEG_00503 HCEG_00503 HCEG_01397 HCEG_01397 HCEG_01423 HCEG_01423 HCEG_00616 HCEG_00616 HCEG_00625 HCEG_00625 HCEG_01470 HCEG_01470 HCEG_01490 HCEG_01490 HCEG_01500 HCEG_01500 HCEG_00693 HCEG_00693 HCEG_01540 HCEG_01540 HCEG_01569 HCEG_01569 HCEG_00792 HCEG_00792 HCEG_00794 HCEG_00794 HCEG_01634 HCEG_01634 HCEG_01679 HCEG_01679 HCEG_00019 HCEG_00019 HCEG_00102 HCEG_00102 HCEG_00908 HCEG_00908 NTH1 NTH1 HCEG_00950 HCEG_00950 HCEG_01756 HCEG_01756 HCEG_01760 HCEG_01760 HCEG_01761 HCEG_01761 HCEG_01781 HCEG_01781 HCEG_01787 HCEG_01787 HCEG_01827 HCEG_01827 HCEG_01097 HCEG_01097 HCEG_00319 HCEG_00319 HCEG_01115 HCEG_01115 HCEG_01128 HCEG_01128 HCEG_00376 HCEG_00376 HCEG_00379 HCEG_00379 HCEG_00465 HCEG_00465 HCEG_01982 HCEG_01982 HCEG_01985 HCEG_01985 HCEG_02846 HCEG_02846 HCEG_02863 HCEG_02863 HCEG_02079 HCEG_02079 HCEG_02916 HCEG_02916 HCEG_02964 HCEG_02964 HCEG_02186 HCEG_02186 HCEG_02196 HCEG_02196 HCEG_02210 HCEG_02210 HCEG_03053 HCEG_03053 HCEG_03103 HCEG_03103 HCEG_02297 HCEG_02297 HCEG_02322 HCEG_02322 HCEG_03144 HCEG_03144 HCEG_03145 HCEG_03145 MCM7 MCM7 HCEG_03223 HCEG_03223 HCEG_02436 HCEG_02436 HCEG_02441 HCEG_02441 HCEG_02461 HCEG_02461 HCEG_02555 HCEG_02555 HCEG_02556 HCEG_02556 HCEG_02649 HCEG_02649 HCEG_02675 HCEG_02675 HCEG_02704 HCEG_02704 HCEG_02758 HCEG_02758 HCEG_02775 HCEG_02775 HCEG_03734 HCEG_03734 HCEG_04557 HCEG_04557 HCEG_03761 HCEG_03761 HCEG_03807 HCEG_03807 HCEG_03879 HCEG_03879 HCEG_04085 HCEG_04085 HCEG_04201 HCEG_04201 HCEG_04214 HCEG_04214 HCEG_04414 HCEG_04414 HCEG_03601 HCEG_03601 PIF1 PIF1 HCEG_03680 HCEG_03680 HCEG_03683 HCEG_03683 HCEG_04515 HCEG_04515 HCEG_04520 HCEG_04520 HCEG_05535 HCEG_05535 UNG1 UNG1 HCEG_04789 HCEG_04789 HCEG_05620 HCEG_05620 HCEG_05628 HCEG_05628 HCEG_05664 HCEG_05664 HCEG_05683 HCEG_05683 HCEG_04920 HCEG_04920 HCEG_05767 HCEG_05767 HCEG_05807 HCEG_05807 HCEG_05029 HCEG_05029 HCEG_05050 HCEG_05050 HCEG_05108 HCEG_05108 HCEG_05134 HCEG_05134 HCEG_05170 HCEG_05170 SLX4 SLX4 HCEG_05307 HCEG_05307 HCEG_05316 HCEG_05316 HCEG_05390 HCEG_05390 HCEG_04606 HCEG_04606 HCEG_05443 HCEG_05443 HCEG_05458 HCEG_05458 HCEG_06375 HCEG_06375 HCEG_07330 HCEG_07330 HCEG_06520 HCEG_06520 HCEG_06721 HCEG_06721 HCEG_06722 HCEG_06722 HCEG_06815 HCEG_06815 HCEG_05980 HCEG_05980 HCEG_06015 HCEG_06015 HCEG_06054 HCEG_06054 HCEG_06125 HCEG_06125 HCEG_07027 HCEG_07027 HCEG_06219 HCEG_06219 HCEG_07035 HCEG_07035 HCEG_07040 HCEG_07040 SLX1 SLX1 HCEG_06342 HCEG_06342 FEN1 FEN1 HCEG_07381 HCEG_07381 HCEG_07586 HCEG_07586 HCEG_07802 HCEG_07802 HCEG_07865 HCEG_07865 HCEG_08056 HCEG_08056 HCEG_08074 HCEG_08074 HCEG_08122 HCEG_08122 HCEG_08197 HCEG_08197 HCEG_08325 HCEG_08325 HCEG_08337 HCEG_08337 HCEG_08379 HCEG_08379 HCEG_08434 HCEG_08434 HCEG_08487 HCEG_08487 HCEG_08488 HCEG_08488 HCEG_08618 HCEG_08618 HCEG_08654 HCEG_08654 HCEG_08731 HCEG_08731 HCEG_08829 HCEG_08829 HCEG_08929 HCEG_08929 HCEG_08962 HCEG_08962 HCEG_08971 HCEG_08971 HCEG_09401 HCEG_09401 HCEG_09418 HCEG_09418
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCEG_00503DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1178 aa)
HCEG_01397DNA mismatch repair protein. (994 aa)
HCEG_01423Predicted protein. (205 aa)
HCEG_00616Uncharacterized protein. (634 aa)
HCEG_00625Uncharacterized protein. (518 aa)
HCEG_01470Hydrolase. (299 aa)
HCEG_01490ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (572 aa)
HCEG_01500SAP domain-containing protein. (421 aa)
HCEG_00693DNA repair protein RAD50. (1298 aa)
HCEG_01540Predicted protein. (125 aa)
HCEG_01569Uncharacterized protein. (554 aa)
HCEG_00792Chromodomain helicase. (1530 aa)
HCEG_00794Chromatin remodelling complex ATPase chain ISW1. (1112 aa)
HCEG_01634DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (941 aa)
HCEG_01679DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2232 aa)
HCEG_00019DNA cross-link repair protein pso2/snm1. (841 aa)
HCEG_00102Uncharacterized protein. (265 aa)
HCEG_00908Rad51 domain-containing protein. (456 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (533 aa)
HCEG_00950Helicase. (732 aa)
HCEG_01756ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (723 aa)
HCEG_01760DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (130 aa)
HCEG_01761DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (450 aa)
HCEG_01781Acetamidase/formamidase. (324 aa)
HCEG_01787DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1234 aa)
HCEG_01827DNA repair and recombination protein RAD54. (830 aa)
HCEG_01097DNA ligase. (945 aa)
HCEG_00319Uncharacterized protein. (180 aa)
HCEG_01115High-affinity nickel transporter. (694 aa)
HCEG_01128Endonuclease. (333 aa)
HCEG_00376TBP associated factor. (1756 aa)
HCEG_00379Uncharacterized protein. (369 aa)
HCEG_00465Pms1-prov protein. (903 aa)
HCEG_01982Zn(2)-C6 fungal-type domain-containing protein. (661 aa)
HCEG_01985ATP-dependent DNA helicase. (1490 aa)
HCEG_02846DNA repair helicase RAD3. (797 aa)
HCEG_02863Uncharacterized protein. (704 aa)
HCEG_02079DEAD-box protein. (507 aa)
HCEG_02916Crossover junction endonuclease mus81. (650 aa)
HCEG_02964DNA ligase. (844 aa)
HCEG_02186Polymerase. (717 aa)
HCEG_02196DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa)
HCEG_02210Chromodomain helicase. (1552 aa)
HCEG_03053DNA polymerase. (1111 aa)
HCEG_03103Histidine triad nucleotide-binding protein. (281 aa)
HCEG_02297DNA replication helicase Dna2. (1609 aa)
HCEG_02322Formamidopyrimidine-DNA glycosylase lyase mutM. (383 aa)
HCEG_03144DNA repair protein RAD16. (848 aa)
HCEG_03145DNA repair protein RAD7. (622 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (818 aa)
HCEG_03223DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1166 aa)
HCEG_02436DNA polymerase iota. (660 aa)
HCEG_02441DNA replication ATPase. (547 aa)
HCEG_02461RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (459 aa)
HCEG_02555DNA mismatch repair protein. (738 aa)
HCEG_02556DNA_MISMATCH_REPAIR_2 domain-containing protein. (216 aa)
HCEG_02649RecA family ATPase Rhp57. (701 aa)
HCEG_02675Cell cycle control protein. (967 aa)
HCEG_02704Uncharacterized protein. (460 aa)
HCEG_02758Uncharacterized protein. (827 aa)
HCEG_02775DsDNA-dependent ATPase. (974 aa)
HCEG_03734XPG I-region protein. (729 aa)
HCEG_04557Tyrosyl-DNA phosphodiesterase. (682 aa)
HCEG_03761DNA ligase. (1023 aa)
HCEG_03807DNA binding protein. (736 aa)
HCEG_03879MutS2 protein. (999 aa)
HCEG_04085Ku70 protein. (655 aa)
HCEG_04201Exonuclease. (830 aa)
HCEG_04214DNA repair protein RAD18. (1161 aa)
HCEG_04414Rad51 family DNA repair protein. (449 aa)
HCEG_03601Uncharacterized protein. (472 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (794 aa)
HCEG_03680DNA polymerase gamma. (1146 aa)
HCEG_03683DNA repair protein RAD5. (1196 aa)
HCEG_04515DNA repair and recombination protein RAD26. (1092 aa)
HCEG_04520DNA polymerase. (1458 aa)
HCEG_05535DNA repair protein. (705 aa)
UNG1Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (886 aa)
HCEG_04789DNA polymerase delta small subunit. (565 aa)
HCEG_05620DNA helicase; Belongs to the MCM family. (1806 aa)
HCEG_05628SNF2 family helicase. (2239 aa)
HCEG_05664RecQ family helicase MusN. (1559 aa)
HCEG_05683DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1162 aa)
HCEG_04920SNF2 family helicase/ATPase. (1181 aa)
HCEG_05767Replication factor C subunit 1. (1071 aa)
HCEG_05807Structural maintenance of chromosomes protein. (1219 aa)
HCEG_05029Helicase swr1. (1674 aa)
HCEG_05050Meiotic recombination protein dmc1; Belongs to the RecA family. (381 aa)
HCEG_05108Uncharacterized protein. (234 aa)
HCEG_05134Uncharacterized protein. (1032 aa)
HCEG_05170C6 zinc finger domain-containing protein. (847 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (843 aa)
HCEG_053078-oxoguanine DNA glycosylase. (422 aa)
HCEG_05316Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (820 aa)
HCEG_05390Helicase C-terminal domain-containing protein. (1142 aa)
HCEG_04606HD superfamily hydrolase. (383 aa)
HCEG_05443DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (909 aa)
HCEG_05458DNA-directed DNA polymerase theta. (934 aa)
HCEG_06375Zn(2)-C6 fungal-type domain-containing protein. (624 aa)
HCEG_07330Uncharacterized protein. (376 aa)
HCEG_06520ATP-dependent helicase NAM7. (1071 aa)
HCEG_06721DNA helicase; Belongs to the MCM family. (965 aa)
HCEG_06722DNA repair helicase rad5,16. (1113 aa)
HCEG_06815Mitotic spindle checkpoint protein. (181 aa)
HCEG_05980Double-strand break repair protein; Belongs to the MRE11/RAD32 family. (1016 aa)
HCEG_06015Uncharacterized protein. (452 aa)
HCEG_06054ERCC4 domain-containing protein. (627 aa)
HCEG_06125ATP-dependent DNA ligase. (1087 aa)
HCEG_07027DNA polymerase. (1637 aa)
HCEG_06219DNA repair helicase RAD25. (1416 aa)
HCEG_07035Predicted protein. (266 aa)
HCEG_07040Endo/exonuclease/phosphatase domain-containing protein. (636 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (421 aa)
HCEG_06342Meiotic recombination protein spo11. (376 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (359 aa)
HCEG_07381RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (467 aa)
HCEG_07586Tyrosyl-DNA phosphodiesterase domain-containing protein. (652 aa)
HCEG_07802Uncharacterized protein. (1198 aa)
HCEG_07865DNA polymerase kappa. (604 aa)
HCEG_08056DNA ATP-dependent helicase. (1676 aa)
HCEG_08074SNF2-family ATP dependent chromatin remodeling factor. (1423 aa)
HCEG_08122SNF2 family helicase/ATPase. (1787 aa)
HCEG_08197Lymphocyte-specific helicase. (983 aa)
HCEG_08325DNA repair protein RAD1. (975 aa)
HCEG_08337ENDO3c domain-containing protein. (270 aa)
HCEG_08379DNA mismatch repair protein. (836 aa)
HCEG_08434DNA excision repair protein Rad2. (1159 aa)
HCEG_08487Uncharacterized protein. (204 aa)
HCEG_08488Uncharacterized protein. (166 aa)
HCEG_08618Uncharacterized protein. (1589 aa)
HCEG_08654ATP-dependent helicase RIS1. (1052 aa)
HCEG_08731DNA lyase. (528 aa)
HCEG_08829DNA mismatch repair protein. (1515 aa)
HCEG_08929Helicase family member. (1510 aa)
HCEG_08962Uracil DNA glycosylase superfamily protein. (371 aa)
HCEG_08971RING-13 protein. (1188 aa)
HCEG_09401DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1712 aa)
HCEG_09418BTB domain-containing protein. (649 aa)
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
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