39 items (Histoplasma capsulatum H88) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCEG_00489	Predicted protein. (234 aa)
	HCEG_01685	Vacuolar sorting-associated protein; Belongs to the AAA ATPase family. (433 aa)
	PIM1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1059 aa)
	HCEG_01763	Matrix AAA protease MAP-1. (917 aa)
	HCEG_00109	Peroxisomal biogenesis factor 6. (1509 aa)
	HCEG_00118	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (439 aa)
	HCEG_01819	Vacuolar sorting protein; Belongs to the AAA ATPase family. (835 aa)
	HCEG_00222	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (422 aa)
	HCEG_00253	26S protease regulatory subunit 6A-B; Belongs to the AAA ATPase family. (464 aa)
	HCEG_02033	26S protease regulatory subunit S10B; Belongs to the AAA ATPase family. (392 aa)
	HCEG_02889	Secretory protein nsfA. (870 aa)
	HCEG_02925	Mitochondrial chaperone BCS1; Belongs to the AAA ATPase family. (501 aa)
	HCEG_02152	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (828 aa)
	HCEG_02367	Intermembrane space AAA protease. (818 aa)
	HCEG_03181	Cell division cycle protein. (763 aa)
	HCEG_03214	Peroxin 1. (1218 aa)
	HCEG_02441	DNA replication ATPase. (547 aa)
	HCEG_02554	Uncharacterized protein. (772 aa)
	HCEG_02776	Uncharacterized protein; Belongs to the ClpA/ClpB family. (925 aa)
	HCEG_03801	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (928 aa)
	HCEG_04021	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (455 aa)
	HCEG_03451	AAA domain-containing protein. (654 aa)
	HCEG_03566	Cell division control protein; Belongs to the AAA ATPase family. (771 aa)
	HCEG_03572	Telomere length regulator protein. (1231 aa)
	HCEG_04723	Spermatogenesis associated 5. (753 aa)
	HCEG_04744	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (389 aa)
	HCEG_04851	AAA domain-containing protein. (1024 aa)
	HCEG_05710	Spastin. (968 aa)
	HCEG_04910	Activator 1 41 kDa subunit. (394 aa)
	HCEG_05767	Replication factor C subunit 1. (1071 aa)
	HCEG_05790	Chromosome transmission fidelity protein. (948 aa)
	HCEG_05912	AAA family ATPase. (982 aa)
	HCEG_06601	YTA7 protein. (1689 aa)
	HCEG_07404	ATP-dependent Clp protease ATP-binding subunit clpX. (621 aa)
	HCEG_07540	Activator 1 37 kDa subunit. (354 aa)
	HCEG_07816	ATPase family AAA domain-containing protein; Belongs to the AAA ATPase family. (428 aa)
	HCEG_08022	Ribosome biogenesis ATPase RIX7. (751 aa)
	HCEG_08376	Cytochrome c1. (836 aa)
	HCEG_09266	Activator 1 subunit 3. (443 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_00109	HCEG_00118	F0U7H0	F0U7H9	Peroxisomal biogenesis factor 6.	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	0.535
HCEG_00109	HCEG_00222	F0U7H0	F0U8A2	Peroxisomal biogenesis factor 6.	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family.	0.525
HCEG_00109	HCEG_00253	F0U7H0	F0U8D3	Peroxisomal biogenesis factor 6.	26S protease regulatory subunit 6A-B; Belongs to the AAA ATPase family.	0.553
HCEG_00109	HCEG_01685	F0U7H0	F0U6J5	Peroxisomal biogenesis factor 6.	Vacuolar sorting-associated protein; Belongs to the AAA ATPase family.	0.546
HCEG_00109	HCEG_02033	F0U7H0	F0UA46	Peroxisomal biogenesis factor 6.	26S protease regulatory subunit S10B; Belongs to the AAA ATPase family.	0.550
HCEG_00109	HCEG_03214	F0U7H0	F0UC53	Peroxisomal biogenesis factor 6.	Peroxin 1.	0.998
HCEG_00109	HCEG_03572	F0U7H0	F0UGQ7	Peroxisomal biogenesis factor 6.	Telomere length regulator protein.	0.487
HCEG_00109	HCEG_04021	F0U7H0	F0UES6	Peroxisomal biogenesis factor 6.	26S protease regulatory subunit 4; Belongs to the AAA ATPase family.	0.563
HCEG_00109	HCEG_04744	F0U7H0	F0UI73	Peroxisomal biogenesis factor 6.	26S protease regulatory subunit 8; Belongs to the AAA ATPase family.	0.565
HCEG_00109	HCEG_05767	F0U7H0	F0UJA7	Peroxisomal biogenesis factor 6.	Replication factor C subunit 1.	0.487
HCEG_00109	HCEG_06601	F0U7H0	F0UMR9	Peroxisomal biogenesis factor 6.	YTA7 protein.	0.535
HCEG_00118	HCEG_00109	F0U7H9	F0U7H0	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Peroxisomal biogenesis factor 6.	0.535
HCEG_00118	HCEG_00222	F0U7H9	F0U8A2	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family.	0.999
HCEG_00118	HCEG_00253	F0U7H9	F0U8D3	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	26S protease regulatory subunit 6A-B; Belongs to the AAA ATPase family.	0.999
HCEG_00118	HCEG_00489	F0U7H9	F0U4H0	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Predicted protein.	0.701
HCEG_00118	HCEG_01685	F0U7H9	F0U6J5	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Vacuolar sorting-associated protein; Belongs to the AAA ATPase family.	0.427
HCEG_00118	HCEG_01819	F0U7H9	F0U7U5	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Vacuolar sorting protein; Belongs to the AAA ATPase family.	0.567
HCEG_00118	HCEG_02033	F0U7H9	F0UA46	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	26S protease regulatory subunit S10B; Belongs to the AAA ATPase family.	0.999
HCEG_00118	HCEG_02152	F0U7H9	F0UAS1	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.694
HCEG_00118	HCEG_02889	F0U7H9	F0UAB2	26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	Secretory protein nsfA.	0.559