(13 nodes) Thioredoxin domain network (Histoplasma capsulatum H88)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	HCEG_00543	Mitochondrial peroxiredoxin PRX1. (222 aa)
	HCEG_00835	Thioredoxin. (337 aa)
	HCEG_00037	Monothiol glutaredoxin-4. (278 aa)
	HCEG_01808	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (191 aa)
	HCEG_01271	Thioredoxin domain-containing protein. (211 aa)
	HCEG_03733	Disulfide isomerase; Belongs to the protein disulfide isomerase family. (381 aa)
	HCEG_04536	Disulfide isomerase. (267 aa)
	HCEG_04537	Disulfide isomerase. (434 aa)
	HCEG_03615	Thioredoxin. (591 aa)
	HCEG_05573	Disulfidisomerase; Belongs to the protein disulfide isomerase family. (515 aa)
	HCEG_05446	Thioredoxin. (493 aa)
	HCEG_06657	Thioredoxin. (242 aa)
	HCEG_08281	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (166 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_00037	HCEG_00835	F0U6N6	F0U6D7	Monothiol glutaredoxin-4.	Thioredoxin.	0.422
HCEG_00543	HCEG_01271	F0U4S7	F0U9M0	Mitochondrial peroxiredoxin PRX1.	Thioredoxin domain-containing protein.	0.573
HCEG_00543	HCEG_01808	F0U4S7	F0U7T4	Mitochondrial peroxiredoxin PRX1.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.850
HCEG_00543	HCEG_03733	F0U4S7	F0UDU5	Mitochondrial peroxiredoxin PRX1.	Disulfide isomerase; Belongs to the protein disulfide isomerase family.	0.796
HCEG_00543	HCEG_04536	F0U4S7	F0UDW0	Mitochondrial peroxiredoxin PRX1.	Disulfide isomerase.	0.796
HCEG_00543	HCEG_04537	F0U4S7	F0UDW1	Mitochondrial peroxiredoxin PRX1.	Disulfide isomerase.	0.796
HCEG_00543	HCEG_05446	F0U4S7	F0ULG1	Mitochondrial peroxiredoxin PRX1.	Thioredoxin.	0.796
HCEG_00543	HCEG_05573	F0U4S7	F0UIA6	Mitochondrial peroxiredoxin PRX1.	Disulfidisomerase; Belongs to the protein disulfide isomerase family.	0.796
HCEG_00543	HCEG_06657	F0U4S7	F0UMX5	Mitochondrial peroxiredoxin PRX1.	Thioredoxin.	0.856
HCEG_00543	HCEG_08281	F0U4S7	F0UT39	Mitochondrial peroxiredoxin PRX1.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.833
HCEG_00835	HCEG_00037	F0U6D7	F0U6N6	Thioredoxin.	Monothiol glutaredoxin-4.	0.422
HCEG_00835	HCEG_05573	F0U6D7	F0UIA6	Thioredoxin.	Disulfidisomerase; Belongs to the protein disulfide isomerase family.	0.408
HCEG_00835	HCEG_06657	F0U6D7	F0UMX5	Thioredoxin.	Thioredoxin.	0.564
HCEG_01271	HCEG_00543	F0U9M0	F0U4S7	Thioredoxin domain-containing protein.	Mitochondrial peroxiredoxin PRX1.	0.573
HCEG_01271	HCEG_01808	F0U9M0	F0U7T4	Thioredoxin domain-containing protein.	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	0.438
HCEG_01808	HCEG_00543	F0U7T4	F0U4S7	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Mitochondrial peroxiredoxin PRX1.	0.850
HCEG_01808	HCEG_01271	F0U7T4	F0U9M0	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Thioredoxin domain-containing protein.	0.438
HCEG_01808	HCEG_03733	F0U7T4	F0UDU5	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Disulfide isomerase; Belongs to the protein disulfide isomerase family.	0.724
HCEG_01808	HCEG_04536	F0U7T4	F0UDW0	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Disulfide isomerase.	0.724
HCEG_01808	HCEG_04537	F0U7T4	F0UDW1	Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Disulfide isomerase.	0.724