(14 nodes) Thiolase-like network (Histoplasma capsulatum H88)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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protein homology

Your Input:
	HCEG_09383	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (437 aa)
	HCEG_01390	Nonspecific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family. (458 aa)
	HCEG_00868	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
	HCEG_00165	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (376 aa)
	HCEG_01094	3-oxoacyl-acyl-carrier-protein synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (564 aa)
	HCEG_00295	Iterative type I polyketide synthase. (2645 aa)
	HCEG_02418	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (417 aa)
	HCEG_02600	Fatty acid synthase. (82 aa)
	HCEG_03696	Polyketide synthase. (2335 aa)
	HCEG_04693	Fatty acid synthase. (1902 aa)
	HCEG_06547	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
	HCEG_06590	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (388 aa)
	HCEG_07720	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (413 aa)
	HCEG_09323	Polyketide synthase. (2479 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_00165	HCEG_00868	F0U7Y1	F0U6S7	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.988
HCEG_00165	HCEG_01094	F0U7Y1	F0U8I2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-oxoacyl-acyl-carrier-protein synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.887
HCEG_00165	HCEG_01390	F0U7Y1	F0U4Y5	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Nonspecific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.853
HCEG_00165	HCEG_02418	F0U7Y1	F0UCA3	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.988
HCEG_00165	HCEG_02600	F0U7Y1	F0UCV9	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Fatty acid synthase.	0.567
HCEG_00165	HCEG_06547	F0U7Y1	F0UMI8	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.974
HCEG_00165	HCEG_06590	F0U7Y1	F0UMQ8	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.983
HCEG_00165	HCEG_07720	F0U7Y1	F0URH8	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.988
HCEG_00165	HCEG_09383	F0U7Y1	F0UW91	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.990
HCEG_00295	HCEG_01094	F0U8M8	F0U8I2	Iterative type I polyketide synthase.	3-oxoacyl-acyl-carrier-protein synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.550
HCEG_00295	HCEG_02600	F0U8M8	F0UCV9	Iterative type I polyketide synthase.	Fatty acid synthase.	0.654
HCEG_00868	HCEG_00165	F0U6S7	F0U7Y1	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.988
HCEG_00868	HCEG_01094	F0U6S7	F0U8I2	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	3-oxoacyl-acyl-carrier-protein synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.490
HCEG_00868	HCEG_01390	F0U6S7	F0U4Y5	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	Nonspecific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.899
HCEG_00868	HCEG_02418	F0U6S7	F0UCA3	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.802
HCEG_00868	HCEG_06547	F0U6S7	F0UMI8	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.716
HCEG_00868	HCEG_06590	F0U6S7	F0UMQ8	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.825
HCEG_00868	HCEG_07720	F0U6S7	F0URH8	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.806
HCEG_00868	HCEG_09383	F0U6S7	F0UW91	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.931
HCEG_01094	HCEG_00165	F0U8I2	F0U7Y1	3-oxoacyl-acyl-carrier-protein synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.887