(15 nodes) Von Willebrand factor A-like domain superfamily network (Histoplasma capsulatum H88)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCEG_05435	Uncharacterized protein; Belongs to the universal ribosomal protein uL11 family. (1485 aa)
	HCEG_05846	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4936 aa)
	HCEG_05004	Uncharacterized protein. (819 aa)
	HCEG_03405	VWFA domain-containing protein. (283 aa)
	HCEG_04085	Ku70 protein. (655 aa)
	HCEG_02223	U-box domain-containing protein. (759 aa)
	HCEG_01837	Protein transporter sec24. (936 aa)
	HCEG_01756	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (723 aa)
	HCEG_00096	26S proteasome regulatory subunit. (302 aa)
	HCEG_01655	Sec23/Sec24 family protein. (1008 aa)
	HCEG_07470	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (505 aa)
	HCEG_06977	Von Willebrand domain-containing protein. (1069 aa)
	HCEG_06621	RNA polymerase II transcription factor B subunit 4. (412 aa)
	HCEG_07284	Von Willebrand RING finger domain-containing protein. (1057 aa)
	HCEG_07233	Transcription factor RfeF. (367 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_01655	HCEG_01837	F0U6G5	F0U7W3	Sec23/Sec24 family protein.	Protein transporter sec24.	0.999
HCEG_01655	HCEG_05435	F0U6G5	F0ULF0	Sec23/Sec24 family protein.	Uncharacterized protein; Belongs to the universal ribosomal protein uL11 family.	0.999
HCEG_01756	HCEG_04085	F0U7C7	F0UF13	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	Ku70 protein.	0.999
HCEG_01837	HCEG_01655	F0U7W3	F0U6G5	Protein transporter sec24.	Sec23/Sec24 family protein.	0.999
HCEG_01837	HCEG_05435	F0U7W3	F0ULF0	Protein transporter sec24.	Uncharacterized protein; Belongs to the universal ribosomal protein uL11 family.	0.999
HCEG_01837	HCEG_07470	F0U7W3	F0UQS8	Protein transporter sec24.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.434
HCEG_04085	HCEG_01756	F0UF13	F0U7C7	Ku70 protein.	ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase.	0.999
HCEG_05435	HCEG_01655	F0ULF0	F0U6G5	Uncharacterized protein; Belongs to the universal ribosomal protein uL11 family.	Sec23/Sec24 family protein.	0.999
HCEG_05435	HCEG_01837	F0ULF0	F0U7W3	Uncharacterized protein; Belongs to the universal ribosomal protein uL11 family.	Protein transporter sec24.	0.999
HCEG_06621	HCEG_07470	F0UMT9	F0UQS8	RNA polymerase II transcription factor B subunit 4.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.999
HCEG_07470	HCEG_01837	F0UQS8	F0U7W3	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	Protein transporter sec24.	0.434
HCEG_07470	HCEG_06621	F0UQS8	F0UMT9	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	RNA polymerase II transcription factor B subunit 4.	0.999