14 items (Histoplasma capsulatum H88) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCEG_02985	Ubiquitin-like domain-containing protein. (152 aa)
	HCEG_01082	3' exoribonuclease. (350 aa)
	HCEG_01354	BZIP domain-containing protein. (252 aa)
	TIF35	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (288 aa)
	HCEG_03011	CAF1 family ribonuclease. (522 aa)
	HCEG_02443	KH domain-containing protein. (551 aa)
	HCEG_03709	mRNA decapping complex subunit Dcp2. (990 aa)
	HCEG_03773	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1126 aa)
	HCEG_06174	BSD domain-containing protein; Belongs to the nucleosome assembly protein (NAP) family. (402 aa)
	HCEG_06940	Uncharacterized protein. (363 aa)
	HCEG_04514	Uncharacterized protein. (277 aa)
	HCEG_03375	Importin beta-2 subunit. (906 aa)
	HCEG_05673	Nuclear pore complex subunit Nup159. (1473 aa)
	HCEG_06210	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1451 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_01082	HCEG_03011	F0U8H0	F0UB42	3' exoribonuclease.	CAF1 family ribonuclease.	0.649
HCEG_01082	HCEG_03375	F0U8H0	F0UFQ3	3' exoribonuclease.	Importin beta-2 subunit.	0.655
HCEG_01082	HCEG_03709	F0U8H0	F0UDS1	3' exoribonuclease.	mRNA decapping complex subunit Dcp2.	0.671
HCEG_01082	HCEG_04514	F0U8H0	F0UHG5	3' exoribonuclease.	Uncharacterized protein.	0.671
HCEG_01082	HCEG_06210	F0U8H0	F0UPP2	3' exoribonuclease.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.770
HCEG_01354	HCEG_06210	F0U4P5	F0UPP2	BZIP domain-containing protein.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.704
HCEG_01354	TIF35	F0U4P5	F0URB5	BZIP domain-containing protein.	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.	0.875
HCEG_02443	HCEG_03011	F0UCF2	F0UB42	KH domain-containing protein.	CAF1 family ribonuclease.	0.728
HCEG_02443	HCEG_03709	F0UCF2	F0UDS1	KH domain-containing protein.	mRNA decapping complex subunit Dcp2.	0.628
HCEG_02443	HCEG_04514	F0UCF2	F0UHG5	KH domain-containing protein.	Uncharacterized protein.	0.628
HCEG_02985	HCEG_06210	F0UAW3	F0UPP2	Ubiquitin-like domain-containing protein.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.704
HCEG_02985	TIF35	F0UAW3	F0URB5	Ubiquitin-like domain-containing protein.	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.	0.875
HCEG_03011	HCEG_01082	F0UB42	F0U8H0	CAF1 family ribonuclease.	3' exoribonuclease.	0.649
HCEG_03011	HCEG_02443	F0UB42	F0UCF2	CAF1 family ribonuclease.	KH domain-containing protein.	0.728
HCEG_03011	HCEG_03709	F0UB42	F0UDS1	CAF1 family ribonuclease.	mRNA decapping complex subunit Dcp2.	0.713
HCEG_03011	HCEG_04514	F0UB42	F0UHG5	CAF1 family ribonuclease.	Uncharacterized protein.	0.713
HCEG_03011	HCEG_06210	F0UB42	F0UPP2	CAF1 family ribonuclease.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.400
HCEG_03375	HCEG_01082	F0UFQ3	F0U8H0	Importin beta-2 subunit.	3' exoribonuclease.	0.655
HCEG_03375	HCEG_05673	F0UFQ3	F0UIW1	Importin beta-2 subunit.	Nuclear pore complex subunit Nup159.	0.426
HCEG_03375	HCEG_06210	F0UFQ3	F0UPP2	Importin beta-2 subunit.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.849