26 items (Histoplasma capsulatum H88) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Predicted Interactions

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Your Input:
	HCEG_01761	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (450 aa)
	HCEG_01760	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (130 aa)
	HCEG_00908	Rad51 domain-containing protein. (456 aa)
	HCEG_00102	Uncharacterized protein. (265 aa)
	HCEG_01490	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (572 aa)
	HCEG_01354	BZIP domain-containing protein. (252 aa)
	HCEG_06780	Asparaginyl-tRNA synthetase. (581 aa)
	HCEG_06490	Serine/threonine protein kinase PRR2. (683 aa)
	HCEG_04968	DUF1767 domain-containing protein. (261 aa)
	HCEG_05664	RecQ family helicase MusN. (1559 aa)
	HCEG_09236	DNA polymerase delta subunit 4. (214 aa)
	HCEG_08936	F-box domain-containing protein. (1572 aa)
	HCEG_07953	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (602 aa)
	SLX1	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (421 aa)
	HCEG_06054	ERCC4 domain-containing protein. (627 aa)
	HCEG_04414	Rad51 family DNA repair protein. (449 aa)
	HCEG_04071	Serine/threonine protein kinase hal4. (477 aa)
	HCEG_03789	Nitrogen permease reactivator protein. (823 aa)
	HCEG_02758	Uncharacterized protein. (827 aa)
	HCEG_02649	RecA family ATPase Rhp57. (701 aa)
	HCEG_03196	3'-5' exonuclease/helicase. (935 aa)
	HCEG_02196	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa)
	HCEG_02985	Ubiquitin-like domain-containing protein. (152 aa)
	HCEG_02916	Crossover junction endonuclease mus81. (650 aa)
	HCEG_00379	Uncharacterized protein. (369 aa)
	HCEG_00311	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (415 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_00102	HCEG_00908	F0U758	F0U772	Uncharacterized protein.	Rad51 domain-containing protein.	0.725
HCEG_00102	HCEG_01490	F0U758	F0U5J1	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.834
HCEG_00102	HCEG_02196	F0U758	F0UB18	Uncharacterized protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.725
HCEG_00102	HCEG_02649	F0U758	F0UD08	Uncharacterized protein.	RecA family ATPase Rhp57.	0.800
HCEG_00102	HCEG_02758	F0U758	F0UDL2	Uncharacterized protein.	Uncharacterized protein.	0.584
HCEG_00102	HCEG_02916	F0U758	F0UAJ2	Uncharacterized protein.	Crossover junction endonuclease mus81.	0.845
HCEG_00102	HCEG_03196	F0U758	F0UC35	Uncharacterized protein.	3'-5' exonuclease/helicase.	0.998
HCEG_00102	HCEG_04414	F0U758	F0UGW0	Uncharacterized protein.	Rad51 family DNA repair protein.	0.630
HCEG_00102	HCEG_04968	F0U758	F0UJF7	Uncharacterized protein.	DUF1767 domain-containing protein.	0.932
HCEG_00102	HCEG_05664	F0U758	F0UIQ0	Uncharacterized protein.	RecQ family helicase MusN.	0.834
HCEG_00102	HCEG_06780	F0U758	F0UNA7	Uncharacterized protein.	Asparaginyl-tRNA synthetase.	0.632
HCEG_00102	HCEG_07953	F0U758	F0US61	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.863
HCEG_00102	SLX1	F0U758	F0UPZ3	Uncharacterized protein.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.764
HCEG_00311	HCEG_00908	F0U8P4	F0U772	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Rad51 domain-containing protein.	0.453
HCEG_00311	HCEG_02196	F0U8P4	F0UB18	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.715
HCEG_00379	HCEG_00908	F0U967	F0U772	Uncharacterized protein.	Rad51 domain-containing protein.	0.725
HCEG_00379	HCEG_01490	F0U967	F0U5J1	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.834
HCEG_00379	HCEG_02196	F0U967	F0UB18	Uncharacterized protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.725
HCEG_00379	HCEG_02649	F0U967	F0UD08	Uncharacterized protein.	RecA family ATPase Rhp57.	0.800
HCEG_00379	HCEG_02758	F0U967	F0UDL2	Uncharacterized protein.	Uncharacterized protein.	0.584