STRINGSTRING
HCEG_04023 HCEG_04023 HCEG_07217 HCEG_07217 HCEG_06376 HCEG_06376 HCEG_05386 HCEG_05386 HCEG_05299 HCEG_05299 HCEG_05083 HCEG_05083 HCEG_05722 HCEG_05722 HCEG_05680 HCEG_05680 HCEG_04695 HCEG_04695 HCEG_05468 HCEG_05468 HCEG_04440 HCEG_04440 HCEG_03484 HCEG_03484 HCEG_04316 HCEG_04316 HCEG_03479 HCEG_03479 HCEG_04268 HCEG_04268 HCEG_04208 HCEG_04208 HCEG_04161 HCEG_04161 HCEG_03498 HCEG_03498 HCEG_09349 HCEG_09349 HCEG_08934 HCEG_08934 HCEG_08780 HCEG_08780 HCEG_08526 HCEG_08526 HCEG_08129 HCEG_08129 HCEG_08042 HCEG_08042 HCEG_08034 HCEG_08034 HCEG_08018 HCEG_08018 HCEG_07939 HCEG_07939 HCEG_07910 HCEG_07910 HCEG_07516 HCEG_07516 HCEG_07470 HCEG_07470 HCEG_07132 HCEG_07132 HCEG_06280 HCEG_06280 HCEG_06278 HCEG_06278 HCEG_06219 HCEG_06219 HCEG_06842 HCEG_06842 HCEG_06841 HCEG_06841 HCEG_06688 HCEG_06688 HCEG_06632 HCEG_06632 HCEG_06621 HCEG_06621 HCEG_07301 HCEG_07301 HCEG_00519 HCEG_00519 HCEG_00807 HCEG_00807 HCEG_00050 HCEG_00050 HCEG_00100 HCEG_00100 HCEG_00162 HCEG_00162 HCEG_00171 HCEG_00171 HCEG_00221 HCEG_00221 HCEG_00264 HCEG_00264 HCEG_00270 HCEG_00270 HCEG_01146 HCEG_01146 HCEG_01151 HCEG_01151 HCEG_01158 HCEG_01158 HCEG_02822 HCEG_02822 HCEG_02846 HCEG_02846 HCEG_02058 HCEG_02058 HCEG_02114 HCEG_02114 HCEG_02156 HCEG_02156 HCEG_02312 HCEG_02312 HCEG_03152 HCEG_03152 HCEG_02327 HCEG_02327 HCEG_02351 HCEG_02351 HCEG_01911 HCEG_01911 HCEG_03909 HCEG_03909 HCEG_03929 HCEG_03929 HCEG_03930 HCEG_03930 HCEG_03956 HCEG_03956
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCEG_04023Cyclin; Belongs to the cyclin family. (381 aa)
HCEG_07217DUF4211 domain-containing protein. (524 aa)
HCEG_06376Uncharacterized protein. (269 aa)
HCEG_05386Transcription initiation factor TFIID subunit 5. (715 aa)
HCEG_05299FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (575 aa)
HCEG_05083DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1307 aa)
HCEG_05722Uncharacterized protein. (719 aa)
HCEG_05680Transcription factor TFIID. (1117 aa)
HCEG_04695Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (720 aa)
HCEG_05468DNA-directed RNA polymerase I. (165 aa)
HCEG_04440RNA polymerase II transcription factor B subunit 5. (120 aa)
HCEG_03484DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1747 aa)
HCEG_04316Tetratricopeptide repeat protein. (1209 aa)
HCEG_03479Transcription initiation factor TFIID. (296 aa)
HCEG_04268Serine/threonine protein kinase bur-1. (554 aa)
HCEG_04208DNA-directed RNA polymerase N. (115 aa)
HCEG_04161Plus3 domain-containing protein. (638 aa)
HCEG_03498Transcription factor TFIIA complex subunit Toa1. (425 aa)
HCEG_09349Serine/threonine protein kinase crk1; Belongs to the protein kinase superfamily. (413 aa)
HCEG_08934Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (298 aa)
HCEG_08780DNA-directed RNA polymerase II. (475 aa)
HCEG_08526BTB domain-containing protein. (866 aa)
HCEG_08129Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (121 aa)
HCEG_08042Uncharacterized protein. (392 aa)
HCEG_08034TFIID subunit. (270 aa)
HCEG_08018Uncharacterized protein. (473 aa)
HCEG_07939FACT complex subunit spt16. (1023 aa)
HCEG_07910Acyl_transf_3 domain-containing protein. (459 aa)
HCEG_07516Cap binding protein. (852 aa)
HCEG_07470General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (505 aa)
HCEG_07132Transcription initiation factor TFIID subunit 12. (668 aa)
HCEG_06280Transcription initiation factor TFIID complex 60 kDa subunit. (629 aa)
HCEG_06278Transcription factor TFIID. (394 aa)
HCEG_06219DNA repair helicase RAD25. (1416 aa)
HCEG_06842Uncharacterized protein. (396 aa)
HCEG_06841Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (131 aa)
HCEG_06688DNA-directed RNA polymerase I. (114 aa)
HCEG_06632Predicted protein. (351 aa)
HCEG_06621RNA polymerase II transcription factor B subunit 4. (412 aa)
HCEG_07301C-type cyclin. (395 aa)
HCEG_00519Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1083 aa)
HCEG_00807CDK-activating kinase assembly factor MAT1. (379 aa)
HCEG_00050Transcription initiation factor tfiid 55 kd subunit. (559 aa)
HCEG_00100Polymerase II polypeptide D. (152 aa)
HCEG_00162Transcription initiation protein. (352 aa)
HCEG_00171Uncharacterized protein. (686 aa)
HCEG_00221RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (885 aa)
HCEG_00264Cyclin; Belongs to the cyclin family. (672 aa)
HCEG_00270Transcription initiation factor TFIID-2. (262 aa)
HCEG_01146Nuclear cap-binding protein subunit 2. (171 aa)
HCEG_01151DNA directed RNA polymerase II 15 kDa subunit. (126 aa)
HCEG_01158Transcription factor spTFIIE alpha subunit. (424 aa)
HCEG_02822RNA polymerase subunit. (236 aa)
HCEG_02846DNA repair helicase RAD3. (797 aa)
HCEG_02058RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (485 aa)
HCEG_02114Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1433 aa)
HCEG_02156Transcription factor iws1. (423 aa)
HCEG_02312TPR domain-containing protein. (402 aa)
HCEG_03152DNA-directed RNA polymerase II. (168 aa)
HCEG_02327Metallothionein-I gene transcription activator. (75 aa)
HCEG_02351RNA polymerase II transcription factor. (644 aa)
HCEG_01911Cell division control protein. (506 aa)
HCEG_03909TATA-binding protein associated factor Taf2. (1247 aa)
HCEG_03929Uncharacterized protein. (668 aa)
HCEG_03930RNA polymerase II subunit 7. (169 aa)
HCEG_03956Transcription initiation factor iif. (387 aa)
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.