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HCEG_04968 HCEG_04968 HCEG_01354 HCEG_01354 HCEG_01423 HCEG_01423 HCEG_01490 HCEG_01490 HCEG_00694 HCEG_00694 HCEG_00695 HCEG_00695 HCEG_00762 HCEG_00762 HCEG_00041 HCEG_00041 HCEG_01732 HCEG_01732 HCEG_00102 HCEG_00102 HCEG_01760 HCEG_01760 HCEG_01761 HCEG_01761 HCEG_00279 HCEG_00279 HCEG_00290 HCEG_00290 HCEG_00311 HCEG_00311 HCEG_01134 HCEG_01134 HCEG_00379 HCEG_00379 HCEG_00422 HCEG_00422 HCEG_02023 HCEG_02023 HCEG_02038 HCEG_02038 HCEG_02876 HCEG_02876 HCEG_02071 HCEG_02071 HCEG_02910 HCEG_02910 HCEG_02948 HCEG_02948 HCEG_02152 HCEG_02152 HCEG_02985 HCEG_02985 HCEG_02352 HCEG_02352 HCEG_03181 HCEG_03181 HCEG_03196 HCEG_03196 MCM7 MCM7 HCEG_02582 HCEG_02582 HCEG_02596 HCEG_02596 HCEG_02675 HCEG_02675 HCEG_01864 HCEG_01864 HCEG_01906 HCEG_01906 HCEG_03789 HCEG_03789 HCEG_03862 HCEG_03862 HCEG_03876 HCEG_03876 HCEG_04071 HCEG_04071 HCEG_04139 HCEG_04139 HCEG_04160 HCEG_04160 HCEG_04189 HCEG_04189 HCEG_03411 HCEG_03411 HCEG_04228 HCEG_04228 HCEG_04257 HCEG_04257 HCEG_04258 HCEG_04258 HCEG_04424 HCEG_04424 HCEG_03610 HCEG_03610 HCEG_03622 HCEG_03622 HCEG_03623 HCEG_03623 HCEG_03665 HCEG_03665 HCEG_03672 HCEG_03672 HCEG_04526 HCEG_04526 HCEG_04725 HCEG_04725 HCEG_05620 HCEG_05620 HCEG_05664 HCEG_05664 HCEG_04834 HCEG_04834 HCEG_04910 HCEG_04910 HCEG_05761 HCEG_05761 HCEG_04965 HCEG_04965 HCEG_05075 HCEG_05075 HCEG_05108 HCEG_05108 HCEG_05185 HCEG_05185 HCEG_05207 HCEG_05207 HCEG_05334 HCEG_05334 HCEG_06462 HCEG_06462 HCEG_06483 HCEG_06483 HCEG_06490 HCEG_06490 HCEG_07365 HCEG_07365 HCEG_06604 HCEG_06604 HCEG_06650 HCEG_06650 HCEG_06721 HCEG_06721 HCEG_06064 HCEG_06064 HCEG_06067 HCEG_06067 HCEG_06921 HCEG_06921 HCEG_06955 HCEG_06955 HCEG_06134 HCEG_06134 HCEG_06226 HCEG_06226 HCEG_07434 HCEG_07434 HCEG_07540 HCEG_07540 HCEG_07550 HCEG_07550 HCEG_07847 HCEG_07847 HCEG_07934 HCEG_07934 HCEG_07953 HCEG_07953 HCEG_07978 HCEG_07978 HCEG_08291 HCEG_08291 HCEG_08445 HCEG_08445 HCEG_08661 HCEG_08661 HCEG_08734 HCEG_08734 HCEG_08735 HCEG_08735 HCEG_08743 HCEG_08743 HCEG_08870 HCEG_08870 HCEG_08919 HCEG_08919 HCEG_08936 HCEG_08936 HCEG_09028 HCEG_09028 HCEG_09228 HCEG_09228 HCEG_09238 HCEG_09238 HCEG_09266 HCEG_09266
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCEG_04968DUF1767 domain-containing protein. (261 aa)
HCEG_01354BZIP domain-containing protein. (252 aa)
HCEG_01423Predicted protein. (205 aa)
HCEG_01490ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (572 aa)
HCEG_00694DNA repair protein RAD1. (401 aa)
HCEG_00695Predicted protein. (77 aa)
HCEG_00762TPR domain-containing protein. (433 aa)
HCEG_00041Serine/threonine protein kinase. (1106 aa)
HCEG_01732Cytoplasm to vacuole targeting Vps64. (760 aa)
HCEG_00102Uncharacterized protein. (265 aa)
HCEG_01760DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (130 aa)
HCEG_01761DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (450 aa)
HCEG_00279HEC/Ndc80p family protein. (734 aa)
HCEG_00290Cell division cycle protein. (803 aa)
HCEG_00311Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (415 aa)
HCEG_01134Nuclear distribution protein NudE. (584 aa)
HCEG_00379Uncharacterized protein. (369 aa)
HCEG_00422Protein kinase domain-containing protein. (362 aa)
HCEG_02023Uncharacterized protein. (138 aa)
HCEG_0203814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (326 aa)
HCEG_02876Spindle assembly checkpoint component mad1. (794 aa)
HCEG_02071Serine/threonine protein kinase. (501 aa)
HCEG_02910UDP-galactopyranose mutase. (533 aa)
HCEG_02948Microtubule associated protein EB1. (250 aa)
HCEG_02152Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (828 aa)
HCEG_02985Ubiquitin-like domain-containing protein. (152 aa)
HCEG_02352Uncharacterized protein. (605 aa)
HCEG_03181Cell division cycle protein. (763 aa)
HCEG_031963'-5' exonuclease/helicase. (935 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (818 aa)
HCEG_02582Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (543 aa)
HCEG_02596Uncharacterized protein. (402 aa)
HCEG_02675Cell cycle control protein. (967 aa)
HCEG_01864Predicted protein. (184 aa)
HCEG_01906Origin recognition complex subunit. (755 aa)
HCEG_03789Nitrogen permease reactivator protein. (823 aa)
HCEG_03862Uncharacterized protein. (84 aa)
HCEG_03876CAP-Gly domain-containing protein. (698 aa)
HCEG_04071Serine/threonine protein kinase hal4. (477 aa)
HCEG_04139Origin recognition complex subunit. (556 aa)
HCEG_04160MRC1 domain-containing protein. (1496 aa)
HCEG_04189ELYS domain-containing protein. (342 aa)
HCEG_03411DNA replication initiation factor Cdc45. (846 aa)
HCEG_04228Histone H2B; Belongs to the histone H2B family. (138 aa)
HCEG_04257Uncharacterized protein. (108 aa)
HCEG_04258Uncharacterized protein. (165 aa)
HCEG_04424Mitotic spindle checkpoint component mad2. (229 aa)
HCEG_03610BRCT domain-containing protein. (921 aa)
HCEG_03622Uncharacterized protein. (452 aa)
HCEG_03623FHA domain-containing protein. (686 aa)
HCEG_03665STE family protein kinase; Belongs to the protein kinase superfamily. (496 aa)
HCEG_03672SsDNA binding protein Ssb3. (117 aa)
HCEG_04526DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (450 aa)
HCEG_04725Phosphatidyl inositol 3-kinase; Belongs to the PI3/PI4-kinase family. (2474 aa)
HCEG_05620DNA helicase; Belongs to the MCM family. (1806 aa)
HCEG_05664RecQ family helicase MusN. (1559 aa)
HCEG_04834Uncharacterized protein. (836 aa)
HCEG_04910Activator 1 41 kDa subunit. (394 aa)
HCEG_05761Activator 1 subunit 5. (352 aa)
HCEG_04965Cyclin-dependent protein kinase; Belongs to the protein kinase superfamily. (315 aa)
HCEG_05075Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (1109 aa)
HCEG_05108Uncharacterized protein. (234 aa)
HCEG_05185DNA damage checkpoint protein rad24; Belongs to the 14-3-3 family. (268 aa)
HCEG_05207Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (999 aa)
HCEG_05334Cyclin-dependent protein kinase; Belongs to the protein kinase superfamily. (400 aa)
HCEG_06462Serine/threonine protein phosphatase. (480 aa)
HCEG_06483Dynein light intermediate chain. (543 aa)
HCEG_06490Serine/threonine protein kinase PRR2. (683 aa)
HCEG_07365Cupin domain-containing protein. (617 aa)
HCEG_06604Origin recognition complex subunit. (686 aa)
HCEG_06650Kinetochore protein nuf2. (464 aa)
HCEG_06721DNA helicase; Belongs to the MCM family. (965 aa)
HCEG_06064Chromo domain-containing protein. (345 aa)
HCEG_06067Uncharacterized protein. (404 aa)
HCEG_06921Single-stranded DNA binding protein p30 subunit. (276 aa)
HCEG_06955DNA helicase; Belongs to the MCM family. (882 aa)
HCEG_06134DNA helicase; Belongs to the MCM family. (718 aa)
HCEG_06226Uncharacterized protein. (194 aa)
HCEG_07434Origin recognition complex subunit. (627 aa)
HCEG_07540Activator 1 37 kDa subunit. (354 aa)
HCEG_07550Serine/threonine protein kinase. (681 aa)
HCEG_07847Serine/threonine protein kinase. (581 aa)
HCEG_07934Nucleolar protein NOP2. (1473 aa)
HCEG_07953Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (602 aa)
HCEG_07978Kinetochore protein spc25. (287 aa)
HCEG_08291Serine/threonine protein kinase cds1. (701 aa)
HCEG_08445Telomere silencing protein Zds1. (803 aa)
HCEG_08661G1/S regulator. (676 aa)
HCEG_08734Spindle assembly checkpoint protein SLDA. (331 aa)
HCEG_08735Spindle assembly checkpoint protein SLDA. (777 aa)
HCEG_08743M-phase inducer phosphatase. (537 aa)
HCEG_08870DNA helicase; Belongs to the MCM family. (877 aa)
HCEG_08919Spindle pole body component. (909 aa)
HCEG_08936F-box domain-containing protein. (1572 aa)
HCEG_09028Checkpoint protein; Belongs to the HUS1 family. (361 aa)
HCEG_09228Spindle assembly checkpoint protein SLDB. (374 aa)
HCEG_09238Uncharacterized protein. (470 aa)
HCEG_09266Activator 1 subunit 3. (443 aa)
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
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