(19 nodes) RAC1 GTPase cycle network (Histoplasma capsulatum H88)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCEG_08907	SH3 and Ded_cyto domain-containing protein; Belongs to the DOCK family. (2202 aa)
	HCEG_08285	Uncharacterized protein. (247 aa)
	HCEG_07468	Predicted protein. (353 aa)
	HCEG_07058	Rac1 GTPase. (199 aa)
	HCEG_06423	Uncharacterized protein. (117 aa)
	HCEG_06422	Uncharacterized protein. (78 aa)
	HCEG_05346	Predicted protein. (306 aa)
	HCEG_05951	Predicted protein. (144 aa)
	HCEG_04474	NADPH oxidase regulator NoxR. (547 aa)
	HCEG_03541	Endoglucanase. (343 aa)
	HCEG_08352	Uncharacterized protein. (247 aa)
	HCEG_04572	Serine/threonine protein kinase. (317 aa)
	HCEG_01436	Predicted protein. (251 aa)
	HCEG_02587	Myosin class II heavy chain. (2442 aa)
	HCEG_02379	Rho guanyl nucleotide exchange factor. (963 aa)
	HCEG_03219	Rho GTPase activator. (738 aa)
	HCEG_02626	Proline-rich. (392 aa)
	HCEG_01180	Uncharacterized protein. (368 aa)
	HCEG_01628	GTPase-activating protein. (785 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_01180	HCEG_01436	F0U924	F0U583	Uncharacterized protein.	Predicted protein.	0.472
HCEG_01180	HCEG_07058	F0U924	F0UPU8	Uncharacterized protein.	Rac1 GTPase.	0.472
HCEG_01436	HCEG_01180	F0U583	F0U924	Predicted protein.	Uncharacterized protein.	0.472
HCEG_01436	HCEG_01628	F0U583	F0U683	Predicted protein.	GTPase-activating protein.	0.764
HCEG_01436	HCEG_02379	F0U583	F0UC64	Predicted protein.	Rho guanyl nucleotide exchange factor.	0.930
HCEG_01436	HCEG_02587	F0U583	F0UCU6	Predicted protein.	Myosin class II heavy chain.	0.702
HCEG_01436	HCEG_02626	F0U583	F0UCY5	Predicted protein.	Proline-rich.	0.522
HCEG_01436	HCEG_03219	F0U583	F0UC58	Predicted protein.	Rho GTPase activator.	0.690
HCEG_01436	HCEG_03541	F0U583	F0UGM6	Predicted protein.	Endoglucanase.	0.996
HCEG_01436	HCEG_04474	F0U583	F0UH72	Predicted protein.	NADPH oxidase regulator NoxR.	0.712
HCEG_01436	HCEG_04572	F0U583	F0UDZ6	Predicted protein.	Serine/threonine protein kinase.	0.803
HCEG_01436	HCEG_05346	F0U583	F0UL27	Predicted protein.	Predicted protein.	0.665
HCEG_01436	HCEG_05951	F0U583	F0UKF5	Predicted protein.	Predicted protein.	0.472
HCEG_01436	HCEG_06422	F0U583	F0ULV7	Predicted protein.	Uncharacterized protein.	0.472
HCEG_01436	HCEG_06423	F0U583	F0ULV8	Predicted protein.	Uncharacterized protein.	0.472
HCEG_01436	HCEG_07468	F0U583	F0UQS6	Predicted protein.	Predicted protein.	0.472
HCEG_01436	HCEG_08285	F0U583	F0UT43	Predicted protein.	Uncharacterized protein.	0.472
HCEG_01436	HCEG_08352	F0U583	F0UTB0	Predicted protein.	Uncharacterized protein.	0.472
HCEG_01436	HCEG_08907	F0U583	F0UUW5	Predicted protein.	SH3 and Ded_cyto domain-containing protein; Belongs to the DOCK family.	0.936
HCEG_01628	HCEG_01436	F0U683	F0U583	GTPase-activating protein.	Predicted protein.	0.764