STRINGSTRING
HCEG_01760 HCEG_01760 HCEG_00908 HCEG_00908 HCEG_00102 HCEG_00102 HCEG_00762 HCEG_00762 HCEG_00693 HCEG_00693 HCEG_01490 HCEG_01490 HCEG_01451 HCEG_01451 HCEG_01423 HCEG_01423 HCEG_00566 HCEG_00566 HCEG_05108 HCEG_05108 HCEG_05724 HCEG_05724 HCEG_05664 HCEG_05664 HCEG_00319 HCEG_00319 HCEG_04789 HCEG_04789 PIF1 PIF1 HCEG_03672 HCEG_03672 HCEG_03677 HCEG_03677 HCEG_04257 HCEG_04257 HCEG_03303 HCEG_03303 HCEG_04108 HCEG_04108 HCEG_03862 HCEG_03862 HCEG_02775 HCEG_02775 HCEG_01864 HCEG_01864 HCEG_02649 HCEG_02649 HCEG_02352 HCEG_02352 HCEG_03053 HCEG_03053 HCEG_02199 HCEG_02199 HCEG_02196 HCEG_02196 HCEG_02922 HCEG_02922 HCEG_02916 HCEG_02916 HCEG_02910 HCEG_02910 HCEG_02023 HCEG_02023 HCEG_00379 HCEG_00379 HCEG_09247 HCEG_09247 HCEG_09236 HCEG_09236 HCEG_08445 HCEG_08445 HCEG_08190 HCEG_08190 HCEG_08122 HCEG_08122 HCEG_08024 HCEG_08024 HCEG_07953 HCEG_07953 HCEG_07934 HCEG_07934 HCEG_07864 HCEG_07864 HCEG_07863 HCEG_07863 HCEG_06226 HCEG_06226 HCEG_06146 HCEG_06146 HCEG_06921 HCEG_06921 HCEG_06067 HCEG_06067 HCEG_06064 HCEG_06064 HCEG_06054 HCEG_06054 HCEG_05980 HCEG_05980 HCEG_07330 HCEG_07330 HCEG_04606 HCEG_04606 HCEG_04258 HCEG_04258 HCEG_04414 HCEG_04414 HCEG_03610 HCEG_03610 HCEG_01827 HCEG_01827 HCEG_01761 HCEG_01761
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCEG_01760DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (130 aa)
HCEG_00908Rad51 domain-containing protein. (456 aa)
HCEG_00102Uncharacterized protein. (265 aa)
HCEG_00762TPR domain-containing protein. (433 aa)
HCEG_00693DNA repair protein RAD50. (1298 aa)
HCEG_01490ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (572 aa)
HCEG_01451RAD52 DNA repair protein RADC. (567 aa)
HCEG_01423Predicted protein. (205 aa)
HCEG_00566BRCT domain-containing protein. (1322 aa)
HCEG_05108Uncharacterized protein. (234 aa)
HCEG_05724Lectin C-type domain-containing protein. (580 aa)
HCEG_05664RecQ family helicase MusN. (1559 aa)
HCEG_00319Uncharacterized protein. (180 aa)
HCEG_04789DNA polymerase delta small subunit. (565 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (794 aa)
HCEG_03672SsDNA binding protein Ssb3. (117 aa)
HCEG_03677Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2803 aa)
HCEG_04257Uncharacterized protein. (108 aa)
HCEG_03303ATP-dependent RNA helicase ROK1. (751 aa)
HCEG_04108SsDNA binding protein. (140 aa)
HCEG_03862Uncharacterized protein. (84 aa)
HCEG_02775DsDNA-dependent ATPase. (974 aa)
HCEG_01864Predicted protein. (184 aa)
HCEG_02649RecA family ATPase Rhp57. (701 aa)
HCEG_02352Uncharacterized protein. (605 aa)
HCEG_03053DNA polymerase. (1111 aa)
HCEG_02199Predicted protein. (122 aa)
HCEG_02196DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa)
HCEG_02922DUF1168 domain-containing protein. (201 aa)
HCEG_02916Crossover junction endonuclease mus81. (650 aa)
HCEG_02910UDP-galactopyranose mutase. (533 aa)
HCEG_02023Uncharacterized protein. (138 aa)
HCEG_00379Uncharacterized protein. (369 aa)
HCEG_09247Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (209 aa)
HCEG_09236DNA polymerase delta subunit 4. (214 aa)
HCEG_08445Telomere silencing protein Zds1. (803 aa)
HCEG_08190Smr domain-containing protein. (233 aa)
HCEG_08122SNF2 family helicase/ATPase. (1787 aa)
HCEG_08024DUF1000 domain-containing protein. (229 aa)
HCEG_07953Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (602 aa)
HCEG_07934Nucleolar protein NOP2. (1473 aa)
HCEG_07864DNA damage response protein RcaA. (351 aa)
HCEG_07863DNA damage response protein RcaA. (248 aa)
HCEG_06226Uncharacterized protein. (194 aa)
HCEG_06146mRNA splicing protein Yju2. (277 aa)
HCEG_06921Single-stranded DNA binding protein p30 subunit. (276 aa)
HCEG_06067Uncharacterized protein. (404 aa)
HCEG_06064Chromo domain-containing protein. (345 aa)
HCEG_06054ERCC4 domain-containing protein. (627 aa)
HCEG_05980Double-strand break repair protein; Belongs to the MRE11/RAD32 family. (1016 aa)
HCEG_07330Uncharacterized protein. (376 aa)
HCEG_04606HD superfamily hydrolase. (383 aa)
HCEG_04258Uncharacterized protein. (165 aa)
HCEG_04414Rad51 family DNA repair protein. (449 aa)
HCEG_03610BRCT domain-containing protein. (921 aa)
HCEG_01827DNA repair and recombination protein RAD54. (830 aa)
HCEG_01761DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (450 aa)
Your Current Organism:
Histoplasma capsulatum H88
NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88
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