25 items (Histoplasma capsulatum H88) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Known Interactions

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Predicted Interactions

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protein homology

Your Input:
	HCEG_04227	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (508 aa)
	HCEG_00612	WD40 repeat-containing protein. (393 aa)
	HCEG_01525	Uncharacterized protein. (126 aa)
	HCEG_00824	Serine/threonine protein kinase. (1019 aa)
	HCEG_01739	WD40 repeat-containing protein. (1400 aa)
	HCEG_01789	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (966 aa)
	HCEG_00196	ATG11 domain-containing protein. (1303 aa)
	HCEG_04558	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (333 aa)
	HCEG_03798	TapA protein. (353 aa)
	HCEG_03922	Uncharacterized protein. (550 aa)
	HCEG_04469	AGC family protein kinase. (427 aa)
	HCEG_06453	Phosphatidylinositol 3-kinase VPS34. (912 aa)
	HCEG_07347	Autophagy-related protein. (118 aa)
	HCEG_06609	Vacuolar targeting protein Atg18. (438 aa)
	HCEG_06903	Uncharacterized protein. (1626 aa)
	HCEG_07745	TorA protein; Belongs to the PI3/PI4-kinase family. (2377 aa)
	HCEG_07947	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (702 aa)
	HCEG_08140	DUF1649 domain-containing protein. (245 aa)
	HCEG_08149	Autophagy-related protein 3. (378 aa)
	HCEG_08634	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (665 aa)
	HCEG_08635	Uncharacterized protein. (86 aa)
	HCEG_08664	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (179 aa)
	HCEG_08940	Autophagy protein Atg2. (2159 aa)
	HCEG_09208	Serine/threonine-protein phosphatase. (325 aa)
	HCEG_09293	Autophagy_act_C domain-containing protein. (265 aa)

Your Current Organism:

Histoplasma capsulatum H88

NCBI taxonomy Id: 544711
Other names: Ajellomyces capsulatus H88, H. capsulatum H88

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCEG_00196	HCEG_00824	F0U812	F0U6C6	ATG11 domain-containing protein.	Serine/threonine protein kinase.	0.986
HCEG_00196	HCEG_01739	F0U812	F0U706	ATG11 domain-containing protein.	WD40 repeat-containing protein.	0.930
HCEG_00196	HCEG_01789	F0U812	F0U7G0	ATG11 domain-containing protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.987
HCEG_00196	HCEG_03922	F0U812	F0UEH7	ATG11 domain-containing protein.	Uncharacterized protein.	0.765
HCEG_00196	HCEG_04227	F0U812	F0UFW3	ATG11 domain-containing protein.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.	0.510
HCEG_00196	HCEG_04469	F0U812	F0UH67	ATG11 domain-containing protein.	AGC family protein kinase.	0.587
HCEG_00196	HCEG_04558	F0U812	F0UDY2	ATG11 domain-containing protein.	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	0.511
HCEG_00196	HCEG_06453	F0U812	F0UM41	ATG11 domain-containing protein.	Phosphatidylinositol 3-kinase VPS34.	0.715
HCEG_00196	HCEG_06609	F0U812	F0UMS7	ATG11 domain-containing protein.	Vacuolar targeting protein Atg18.	0.520
HCEG_00196	HCEG_06903	F0U812	F0UNY4	ATG11 domain-containing protein.	Uncharacterized protein.	0.679
HCEG_00196	HCEG_07347	F0U812	F0UME0	ATG11 domain-containing protein.	Autophagy-related protein.	0.546
HCEG_00196	HCEG_07745	F0U812	F0URK3	ATG11 domain-containing protein.	TorA protein; Belongs to the PI3/PI4-kinase family.	0.940
HCEG_00196	HCEG_07947	F0U812	F0US55	ATG11 domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]	0.655
HCEG_00196	HCEG_08140	F0U812	F0USP8	ATG11 domain-containing protein.	DUF1649 domain-containing protein.	0.948
HCEG_00196	HCEG_08149	F0U812	F0USQ7	ATG11 domain-containing protein.	Autophagy-related protein 3.	0.511
HCEG_00196	HCEG_08634	F0U812	F0UU42	ATG11 domain-containing protein.	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily.	0.964
HCEG_00196	HCEG_08635	F0U812	F0UU43	ATG11 domain-containing protein.	Uncharacterized protein.	0.842
HCEG_00196	HCEG_08664	F0U812	F0UU72	ATG11 domain-containing protein.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	0.637
HCEG_00196	HCEG_08940	F0U812	F0UUZ8	ATG11 domain-containing protein.	Autophagy protein Atg2.	0.511
HCEG_00196	HCEG_09208	F0U812	F0UVR6	ATG11 domain-containing protein.	Serine/threonine-protein phosphatase.	0.943