(16 nodes) Mixed, incl. Cell wall integrity MAPK cascade, and Protein phosphatase network (Histoplasma capsulatum H143)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCDG_00634	MAP kinase skh1/pek1; Belongs to the protein kinase superfamily. (344 aa)
	HCDG_00717	Tyrosine phosphatase MSG5. (826 aa)
	HCDG_00838	Mitogen-activated protein kinase. (421 aa)
	HCDG_00376	Rhodanese domain-containing protein. (370 aa)
	HCDG_02852	Integral membrane protein. (1175 aa)
	HCDG_03490	Uncharacterized protein. (332 aa)
	HCDG_05155	Glycogen synthase kinase; Belongs to the protein kinase superfamily. (291 aa)
	HCDG_06493	CAMK kinase. (640 aa)
	HCDG_06704	Protein phosphatase 2C. (611 aa)
	HCDG_06866	Hr1 domain-containing protein. (82 aa)
	HCDG_06868	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (766 aa)
	HCDG_07334	TRAF-type zinc finger protein. (474 aa)
	HCDG_07774	Protein phosphatase 2c. (675 aa)
	HCDG_08519	Protein-tyrosine phosphatase. (497 aa)
	HCDG_09033	MAP kinase Hogp. (252 aa)
	HCDG_09425	Calcium/calmodulin-dependent protein kinase. (522 aa)

Your Current Organism:

Histoplasma capsulatum H143

NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCDG_00376	HCDG_00634	C6H555	C6H1Q2	Rhodanese domain-containing protein.	MAP kinase skh1/pek1; Belongs to the protein kinase superfamily.	0.623
HCDG_00376	HCDG_00717	C6H555	C6H1Y5	Rhodanese domain-containing protein.	Tyrosine phosphatase MSG5.	0.545
HCDG_00376	HCDG_00838	C6H555	C6H2A6	Rhodanese domain-containing protein.	Mitogen-activated protein kinase.	0.927
HCDG_00376	HCDG_02852	C6H555	C6H9H1	Rhodanese domain-containing protein.	Integral membrane protein.	0.614
HCDG_00376	HCDG_03490	C6H555	C6HBU1	Rhodanese domain-containing protein.	Uncharacterized protein.	0.614
HCDG_00376	HCDG_05155	C6H555	C6HGR4	Rhodanese domain-containing protein.	Glycogen synthase kinase; Belongs to the protein kinase superfamily.	0.615
HCDG_00376	HCDG_06704	C6H555	C6HKH3	Rhodanese domain-containing protein.	Protein phosphatase 2C.	0.706
HCDG_00376	HCDG_07774	C6H555	C6HNJ3	Rhodanese domain-containing protein.	Protein phosphatase 2c.	0.409
HCDG_00376	HCDG_08519	C6H555	C6HRD4	Rhodanese domain-containing protein.	Protein-tyrosine phosphatase.	0.778
HCDG_00376	HCDG_09033	C6H555	C6HS52	Rhodanese domain-containing protein.	MAP kinase Hogp.	0.985
HCDG_00634	HCDG_00376	C6H1Q2	C6H555	MAP kinase skh1/pek1; Belongs to the protein kinase superfamily.	Rhodanese domain-containing protein.	0.623
HCDG_00634	HCDG_00717	C6H1Q2	C6H1Y5	MAP kinase skh1/pek1; Belongs to the protein kinase superfamily.	Tyrosine phosphatase MSG5.	0.460
HCDG_00634	HCDG_00838	C6H1Q2	C6H2A6	MAP kinase skh1/pek1; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.990
HCDG_00634	HCDG_02852	C6H1Q2	C6H9H1	MAP kinase skh1/pek1; Belongs to the protein kinase superfamily.	Integral membrane protein.	0.584
HCDG_00634	HCDG_03490	C6H1Q2	C6HBU1	MAP kinase skh1/pek1; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.578
HCDG_00634	HCDG_05155	C6H1Q2	C6HGR4	MAP kinase skh1/pek1; Belongs to the protein kinase superfamily.	Glycogen synthase kinase; Belongs to the protein kinase superfamily.	0.819
HCDG_00634	HCDG_06493	C6H1Q2	C6HJW2	MAP kinase skh1/pek1; Belongs to the protein kinase superfamily.	CAMK kinase.	0.977
HCDG_00634	HCDG_06704	C6H1Q2	C6HKH3	MAP kinase skh1/pek1; Belongs to the protein kinase superfamily.	Protein phosphatase 2C.	0.612
HCDG_00634	HCDG_06866	C6H1Q2	C6HKY5	MAP kinase skh1/pek1; Belongs to the protein kinase superfamily.	Hr1 domain-containing protein.	0.773
HCDG_00634	HCDG_06868	C6H1Q2	C6HKY7	MAP kinase skh1/pek1; Belongs to the protein kinase superfamily.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.791