STRINGSTRING
HCDG_00550 HCDG_00550 HCDG_00642 HCDG_00642 HCDG_00723 HCDG_00723 HCDG_00763 HCDG_00763 HCDG_00764 HCDG_00764 HCDG_00765 HCDG_00765 HCDG_00766 HCDG_00766 HCDG_00830 HCDG_00830 HCDG_00967 HCDG_00967 HCDG_00968 HCDG_00968 HCDG_00969 HCDG_00969 HCDG_01177 HCDG_01177 HCDG_00014 HCDG_00014 HCDG_00064 HCDG_00064 HCDG_00199 HCDG_00199 HCDG_00325 HCDG_00325 HCDG_00335 HCDG_00335 HCDG_00336 HCDG_00336 HCDG_00382 HCDG_00382 HCDG_00385 HCDG_00385 HCDG_00386 HCDG_00386 HCDG_01725 HCDG_01725 HCDG_01961 HCDG_01961 HCDG_02051 HCDG_02051 HCDG_02167 HCDG_02167 HCDG_02168 HCDG_02168 HCDG_02191 HCDG_02191 HCDG_02270 HCDG_02270 HCDG_02311 HCDG_02311 HCDG_01539 HCDG_01539 HCDG_01592 HCDG_01592 HCDG_01593 HCDG_01593 HCDG_01632 HCDG_01632 HCDG_02486 HCDG_02486 HCDG_02496 HCDG_02496 HCDG_02679 HCDG_02679 HCDG_02765 HCDG_02765 HCDG_02778 HCDG_02778 HCDG_02792 HCDG_02792 HCDG_02809 HCDG_02809 HCDG_03139 HCDG_03139 HCDG_03183 HCDG_03183 HCDG_03248 HCDG_03248 HCDG_03249 HCDG_03249 HCDG_03318 HCDG_03318 HCDG_03831 HCDG_03831 HCDG_03857 HCDG_03857 HCDG_03938 HCDG_03938 HCDG_03350 HCDG_03350 MCM7 MCM7 HCDG_03377 HCDG_03377 HCDG_03389 HCDG_03389 HCDG_03519 HCDG_03519 HCDG_04227 HCDG_04227 HCDG_04309 HCDG_04309 HCDG_04310 HCDG_04310 HCDG_04359 HCDG_04359 HCDG_04434 HCDG_04434 HCDG_04476 HCDG_04476 HCDG_04922 HCDG_04922 HCDG_04530 HCDG_04530 HCDG_04683 HCDG_04683 HCDG_05357 HCDG_05357 HCDG_05071 HCDG_05071 HCDG_05173 HCDG_05173 HCDG_05181 HCDG_05181 HCDG_05524 HCDG_05524 HCDG_05547 HCDG_05547 HCDG_05757 HCDG_05757 HCDG_06236 HCDG_06236 HCDG_06242 HCDG_06242 HCDG_05838 HCDG_05838 HCDG_05839 HCDG_05839 HCDG_05913 HCDG_05913 HCDG_05922 HCDG_05922 HCDG_05959 HCDG_05959 HCDG_06040 HCDG_06040 HCDG_06041 HCDG_06041 HCDG_06104 HCDG_06104 HCDG_06340 HCDG_06340 HCDG_06388 HCDG_06388 HCDG_06409 HCDG_06409 HCDG_06490 HCDG_06490 HCDG_06497 HCDG_06497 HCDG_06520 HCDG_06520 HCDG_06708 HCDG_06708 HCDG_06743 HCDG_06743 HCDG_06775 HCDG_06775 HCDG_06884 HCDG_06884 HCDG_06901 HCDG_06901 HCDG_06902 HCDG_06902 HCDG_06976 HCDG_06976 HCDG_07529 HCDG_07529 HCDG_07227 HCDG_07227 HCDG_07317 HCDG_07317 HCDG_07318 HCDG_07318 HCDG_07321 HCDG_07321 HCDG_07428 HCDG_07428 HCDG_07461 HCDG_07461 HCDG_07462 HCDG_07462 HCDG_07644 HCDG_07644 HCDG_07798 HCDG_07798 HCDG_07961 HCDG_07961 HCDG_08024 HCDG_08024 HCDG_08026 HCDG_08026 HCDG_08065 HCDG_08065 HCDG_08112 HCDG_08112 HCDG_08190 HCDG_08190 HCDG_08381 HCDG_08381 FEN1 FEN1 HCDG_08919 HCDG_08919 HCDG_08729 HCDG_08729 HCDG_08743 HCDG_08743 HCDG_08440 HCDG_08440 HCDG_08967 HCDG_08967 HCDG_09052 HCDG_09052 HCDG_09318 HCDG_09318
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_00550Cell division cycle protein. (803 aa)
HCDG_00642Uncharacterized protein. (369 aa)
HCDG_00723DNA mismatch repair protein. (820 aa)
HCDG_00763Uncharacterized protein. (200 aa)
HCDG_00764DNA mismatch repair protein. (312 aa)
HCDG_00765DNA mismatch repair protein. (519 aa)
HCDG_00766Rhodanese domain-containing protein. (166 aa)
HCDG_00830BRCT domain-containing protein. (1322 aa)
HCDG_00967DNA repair protein RAD50. (1421 aa)
HCDG_00968DNA repair protein RAD1. (401 aa)
HCDG_00969Uncharacterized protein. (77 aa)
HCDG_01177RECA_2 domain-containing protein. (423 aa)
HCDG_00014DNA replication factor C subunit Rfc3. (345 aa)
HCDG_00064Meiotic recombination protein; Belongs to the RecA family. (381 aa)
HCDG_00199DNA replication factor C subunit Rfc2. (394 aa)
HCDG_00325DNA polymerase delta small subunit. (565 aa)
HCDG_00335Topoisomerase I. (109 aa)
HCDG_00336Topoisomerase 1-associated factor 1. (810 aa)
HCDG_00382Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (346 aa)
HCDG_00385Uncharacterized protein. (711 aa)
HCDG_00386Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1490 aa)
HCDG_01725Uncharacterized protein. (451 aa)
HCDG_01961Checkpoint protein; Belongs to the HUS1 family. (364 aa)
HCDG_02051Serine/threonine protein kinase. (390 aa)
HCDG_02167Acetamidase/formamidase. (324 aa)
HCDG_02168Acetamidase/formamidase. (180 aa)
HCDG_02191DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (630 aa)
HCDG_02270DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2111 aa)
HCDG_02311DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (941 aa)
HCDG_01539DNA mismatch repair protein. (1003 aa)
HCDG_01592RAD52 DNA repair protein RADC. (204 aa)
HCDG_01593RAD52 DNA repair protein RADC. (276 aa)
HCDG_01632ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (572 aa)
HCDG_02486Origin recognition complex subunit. (755 aa)
HCDG_02496DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (272 aa)
HCDG_02679Serine/threonine protein kinase. (501 aa)
HCDG_02765Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (828 aa)
HCDG_02778Uncharacterized protein. (966 aa)
HCDG_02792Uncharacterized protein. (309 aa)
HCDG_02809DNA repair protein RAD51. (249 aa)
HCDG_03139Helicase C-terminal domain-containing protein. (1055 aa)
HCDG_03183DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (504 aa)
HCDG_03248Vezatin domain-containing protein. (314 aa)
HCDG_03249Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (548 aa)
HCDG_03318DNA polymerase epsilon subunit B. (644 aa)
HCDG_03831RecA family ATPase Rhp57. (701 aa)
HCDG_03857Cell cycle checkpoint protein rad17. (967 aa)
HCDG_03938Uncharacterized protein. (772 aa)
HCDG_03350DNA mismatch repair protein. (1114 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (698 aa)
HCDG_033773'-5' exonuclease/helicase. (947 aa)
HCDG_03389Cell division control protein; Belongs to the CDC6/cdc18 family. (553 aa)
HCDG_03519DNA polymerase. (1053 aa)
HCDG_04227G1/S regulator. (676 aa)
HCDG_04309M-phase inducer phosphatase. (437 aa)
HCDG_04310DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (284 aa)
HCDG_04359Meiosis induction protein kinase. (761 aa)
HCDG_04434DNA mismatch repair protein. (1515 aa)
HCDG_04476DNA helicase; Belongs to the MCM family. (857 aa)
HCDG_04922Zn(2)-C6 fungal-type domain-containing protein. (645 aa)
HCDG_04530Meiotic recombination protein; Belongs to the MRE11/RAD32 family. (503 aa)
HCDG_04683DNA helicase; Belongs to the MCM family. (718 aa)
HCDG_05357Origin recognition complex subunit. (686 aa)
HCDG_05071Origin recognition complex subunit Orc5. (485 aa)
HCDG_05173Activator 1 37 kDa subunit. (354 aa)
HCDG_05181AGC kinase. (590 aa)
HCDG_05524DNA polymerase kappa. (604 aa)
HCDG_05547Serine/threonine protein kinase. (631 aa)
HCDG_05757Uncharacterized protein. (320 aa)
HCDG_06236DNA polymerase. (1458 aa)
HCDG_06242DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (450 aa)
HCDG_05838Uncharacterized protein. (112 aa)
HCDG_05839Mismatch repair protein. (627 aa)
HCDG_05913PSF1 domain-containing protein. (277 aa)
HCDG_05922Sister chromatid cohesion protein Ctf8. (268 aa)
HCDG_05959DNA polymerase iota. (730 aa)
HCDG_06040Uncharacterized protein. (1031 aa)
HCDG_06041DNA replication complex GINS protein psf3. (159 aa)
HCDG_06104DNA replication ATP-dependent helicase dna2. (1609 aa)
HCDG_06340DNA helicase; Belongs to the MCM family. (1758 aa)
HCDG_06388RecQ family helicase MusN. (1559 aa)
HCDG_06409DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1111 aa)
HCDG_06490Activator 1 38 kDa subunit. (325 aa)
HCDG_06497Replication factor C subunit 1. (1071 aa)
HCDG_06520Chromosome transmission fidelity protein. (939 aa)
HCDG_06708BRCT domain-containing protein. (891 aa)
HCDG_06743DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (633 aa)
HCDG_06775Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2777 aa)
HCDG_06884Protein kinase. (713 aa)
HCDG_06901Uncharacterized protein. (187 aa)
HCDG_06902DNA mismatch repair protein. (449 aa)
HCDG_06976MutS2 protein. (999 aa)
HCDG_07529DNA polymerase. (1503 aa)
HCDG_07227DNA helicase; Belongs to the MCM family. (965 aa)
HCDG_07317Uncharacterized protein. (244 aa)
HCDG_07318Uncharacterized protein. (61 aa)
HCDG_07321Mitotic spindle checkpoint protein. (357 aa)
HCDG_07428Single-stranded DNA binding protein p30 subunit. (265 aa)
HCDG_07461DNA replication licensing factor mcm2; Belongs to the MCM family. (542 aa)
HCDG_07462DNA replication licensing factor mcm2. (252 aa)
HCDG_07644Uncharacterized protein. (103 aa)
HCDG_07798DNA replication initiation factor Cdc45. (846 aa)
HCDG_07961AAA domain-containing protein. (1230 aa)
HCDG_08024DNA primase; Belongs to the eukaryotic-type primase small subunit family. (567 aa)
HCDG_08026Exonuclease. (829 aa)
HCDG_08065MRC1 domain-containing protein. (1491 aa)
HCDG_08112Rad51 family DNA repair protein. (455 aa)
HCDG_08190DNA damage and replication checkpoint protein Rfx1. (558 aa)
HCDG_08381Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (541 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
HCDG_08919Sister chromatid cohesion acetyltransferase Eco1. (480 aa)
HCDG_08729Chromosome segregation protein. (849 aa)
HCDG_08743Tousled-like kinase. (489 aa)
HCDG_08440Serine/threonine protein kinase. (1106 aa)
HCDG_08967Pregnancy upregulated non-ubiquitously expressed CaM kinase. (653 aa)
HCDG_09052DNA mismatch repair protein. (826 aa)
HCDG_09318Origin recognition complex subunit Orc2. (556 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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