STRINGSTRING
HCDG_00642 HCDG_00642 HCDG_00830 HCDG_00830 HCDG_00967 HCDG_00967 HCDG_00968 HCDG_00968 HCDG_00969 HCDG_00969 HCDG_01177 HCDG_01177 HCDG_00064 HCDG_00064 HCDG_00199 HCDG_00199 HCDG_00385 HCDG_00385 HCDG_01961 HCDG_01961 HCDG_02191 HCDG_02191 HCDG_01592 HCDG_01592 HCDG_01593 HCDG_01593 HCDG_01632 HCDG_01632 HCDG_02809 HCDG_02809 HCDG_03139 HCDG_03139 HCDG_03831 HCDG_03831 HCDG_03857 HCDG_03857 HCDG_03938 HCDG_03938 HCDG_03377 HCDG_03377 HCDG_04530 HCDG_04530 HCDG_06242 HCDG_06242 HCDG_06104 HCDG_06104 HCDG_06388 HCDG_06388 HCDG_06775 HCDG_06775 HCDG_07428 HCDG_07428 HCDG_07644 HCDG_07644 HCDG_07961 HCDG_07961 HCDG_08026 HCDG_08026 HCDG_08112 HCDG_08112 HCDG_08381 HCDG_08381
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_00642Uncharacterized protein. (369 aa)
HCDG_00830BRCT domain-containing protein. (1322 aa)
HCDG_00967DNA repair protein RAD50. (1421 aa)
HCDG_00968DNA repair protein RAD1. (401 aa)
HCDG_00969Uncharacterized protein. (77 aa)
HCDG_01177RECA_2 domain-containing protein. (423 aa)
HCDG_00064Meiotic recombination protein; Belongs to the RecA family. (381 aa)
HCDG_00199DNA replication factor C subunit Rfc2. (394 aa)
HCDG_00385Uncharacterized protein. (711 aa)
HCDG_01961Checkpoint protein; Belongs to the HUS1 family. (364 aa)
HCDG_02191DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (630 aa)
HCDG_01592RAD52 DNA repair protein RADC. (204 aa)
HCDG_01593RAD52 DNA repair protein RADC. (276 aa)
HCDG_01632ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (572 aa)
HCDG_02809DNA repair protein RAD51. (249 aa)
HCDG_03139Helicase C-terminal domain-containing protein. (1055 aa)
HCDG_03831RecA family ATPase Rhp57. (701 aa)
HCDG_03857Cell cycle checkpoint protein rad17. (967 aa)
HCDG_03938Uncharacterized protein. (772 aa)
HCDG_033773'-5' exonuclease/helicase. (947 aa)
HCDG_04530Meiotic recombination protein; Belongs to the MRE11/RAD32 family. (503 aa)
HCDG_06242DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (450 aa)
HCDG_06104DNA replication ATP-dependent helicase dna2. (1609 aa)
HCDG_06388RecQ family helicase MusN. (1559 aa)
HCDG_06775Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2777 aa)
HCDG_07428Single-stranded DNA binding protein p30 subunit. (265 aa)
HCDG_07644Uncharacterized protein. (103 aa)
HCDG_07961AAA domain-containing protein. (1230 aa)
HCDG_08026Exonuclease. (829 aa)
HCDG_08112Rad51 family DNA repair protein. (455 aa)
HCDG_08381Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (541 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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