STRINGSTRING
HCDG_03007 HCDG_03007 HCDG_00662 HCDG_00662 HCDG_00968 HCDG_00968 HCDG_00969 HCDG_00969 HCDG_00240 HCDG_00240 HCDG_00277 HCDG_00277 HCDG_00382 HCDG_00382 HCDG_01735 HCDG_01735 HCDG_01770 HCDG_01770 HCDG_01961 HCDG_01961 HCDG_01982 HCDG_01982 HCDG_02051 HCDG_02051 HCDG_02065 HCDG_02065 HCDG_02561 HCDG_02561 HCDG_02679 HCDG_02679 HCDG_03155 HCDG_03155 HCDG_03242 HCDG_03242 HCDG_03857 HCDG_03857 HCDG_03389 HCDG_03389 HCDG_03405 HCDG_03405 HCDG_03657 HCDG_03657 HCDG_03703 HCDG_03703 HCDG_04301 HCDG_04301 HCDG_04302 HCDG_04302 HCDG_04882 HCDG_04882 HCDG_04883 HCDG_04883 HCDG_04530 HCDG_04530 HCDG_04600 HCDG_04600 HCDG_04691 HCDG_04691 HCDG_04692 HCDG_04692 HCDG_05181 HCDG_05181 HCDG_05547 HCDG_05547 HCDG_06242 HCDG_06242 HCDG_06375 HCDG_06375 HCDG_06708 HCDG_06708 HCDG_06720 HCDG_06720 HCDG_06721 HCDG_06721 HCDG_06762 HCDG_06762 HCDG_06775 HCDG_06775 HCDG_06843 HCDG_06843 HCDG_08065 HCDG_08065 HCDG_08121 HCDG_08121 HCDG_08196 HCDG_08196 HCDG_08743 HCDG_08743 HCDG_08440 HCDG_08440 HCDG_08967 HCDG_08967
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_03007C2H2 finger domain-containing protein. (462 aa)
HCDG_00662Phosphoprotein phosphatase A. (617 aa)
HCDG_00968DNA repair protein RAD1. (401 aa)
HCDG_00969Uncharacterized protein. (77 aa)
HCDG_00240Dual specificity protein kinase Ttk. (811 aa)
HCDG_00277Uncharacterized protein. (836 aa)
HCDG_00382Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (346 aa)
HCDG_01735Spindle assembly checkpoint protein SLDB. (374 aa)
HCDG_01770Tyrosine phosphatase CDC14. (578 aa)
HCDG_01961Checkpoint protein; Belongs to the HUS1 family. (364 aa)
HCDG_01982CLPTM1 domain-containing protein. (525 aa)
HCDG_02051Serine/threonine protein kinase. (390 aa)
HCDG_02065Meiosis-specific protein Hop1. (750 aa)
HCDG_02561Chromosome segregation protein. (1587 aa)
HCDG_02679Serine/threonine protein kinase. (501 aa)
HCDG_03155Cell division control protein. (463 aa)
HCDG_03242Serine/threonine protein phosphatase PP1. (154 aa)
HCDG_03857Cell cycle checkpoint protein rad17. (967 aa)
HCDG_03389Cell division control protein; Belongs to the CDC6/cdc18 family. (553 aa)
HCDG_03405Protein kinase. (397 aa)
HCDG_03657Crossover junction endonuclease mus81. (650 aa)
HCDG_03703Spindle assembly checkpoint component mad1. (794 aa)
HCDG_04301Mitotic spindle checkpoint component mad3. (331 aa)
HCDG_04302Protein kinase domain-containing protein. (597 aa)
HCDG_04882BRCT domain-containing protein. (533 aa)
HCDG_04883DNA damage repair protein. (639 aa)
HCDG_04530Meiotic recombination protein; Belongs to the MRE11/RAD32 family. (503 aa)
HCDG_04600ERCC4 domain-containing protein. (197 aa)
HCDG_04691Serine/threonine protein phosphatase. (425 aa)
HCDG_04692Uncharacterized protein. (213 aa)
HCDG_05181AGC kinase. (590 aa)
HCDG_05547Serine/threonine protein kinase. (631 aa)
HCDG_06242DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (450 aa)
HCDG_06375Uncharacterized protein. (532 aa)
HCDG_06708BRCT domain-containing protein. (891 aa)
HCDG_06720Uncharacterized protein. (452 aa)
HCDG_06721Uncharacterized protein. (685 aa)
HCDG_06762Protein kinase; Belongs to the protein kinase superfamily. (482 aa)
HCDG_06775Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2777 aa)
HCDG_06843Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (530 aa)
HCDG_08065MRC1 domain-containing protein. (1491 aa)
HCDG_08121Mitotic spindle checkpoint component mad2. (229 aa)
HCDG_08196Protein kinase. (1545 aa)
HCDG_08743Tousled-like kinase. (489 aa)
HCDG_08440Serine/threonine protein kinase. (1106 aa)
HCDG_08967Pregnancy upregulated non-ubiquitously expressed CaM kinase. (653 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.