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HCDG_02061 HCDG_02061 MCM7 MCM7 HCDG_05913 HCDG_05913 HCDG_06041 HCDG_06041 HCDG_06340 HCDG_06340 HCDG_07227 HCDG_07227 HCDG_07461 HCDG_07461 HCDG_07462 HCDG_07462 HCDG_08381 HCDG_08381
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_02061Helicase family member. (1510 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (698 aa)
HCDG_05913PSF1 domain-containing protein. (277 aa)
HCDG_06041DNA replication complex GINS protein psf3. (159 aa)
HCDG_06340DNA helicase; Belongs to the MCM family. (1758 aa)
HCDG_07227DNA helicase; Belongs to the MCM family. (965 aa)
HCDG_07461DNA replication licensing factor mcm2; Belongs to the MCM family. (542 aa)
HCDG_07462DNA replication licensing factor mcm2. (252 aa)
HCDG_08381Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (541 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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