STRINGSTRING
HCDG_06047 HCDG_06047 HCDG_06958 HCDG_06958 HCDG_08381 HCDG_08381 HCDG_00967 HCDG_00967 HCDG_00325 HCDG_00325 HCDG_02191 HCDG_02191 HCDG_01565 HCDG_01565 HCDG_02856 HCDG_02856 HCDG_03034 HCDG_03034 HCDG_04768 HCDG_04768 HCDG_05443 HCDG_05443
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_06047Uncharacterized protein. (605 aa)
HCDG_06958Uncharacterized protein. (84 aa)
HCDG_08381Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (541 aa)
HCDG_00967DNA repair protein RAD50. (1421 aa)
HCDG_00325DNA polymerase delta small subunit. (565 aa)
HCDG_02191DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (630 aa)
HCDG_01565Uncharacterized protein. (314 aa)
HCDG_02856Uncharacterized protein. (168 aa)
HCDG_03034Telomere_reg-2 domain-containing protein. (940 aa)
HCDG_04768Uncharacterized protein. (171 aa)
HCDG_05443Uncharacterized protein. (108 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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