STRINGSTRING
HCDG_00014 HCDG_00014 HCDG_01177 HCDG_01177 UNG1 UNG1 HCDG_03831 HCDG_03831 HCDG_03857 HCDG_03857 HCDG_03888 HCDG_03888 HCDG_03938 HCDG_03938 HCDG_03956 HCDG_03956 HCDG_03980 HCDG_03980 HCDG_04004 HCDG_04004 HCDG_03350 HCDG_03350 MCM7 MCM7 HCDG_03377 HCDG_03377 HCDG_03430 HCDG_03430 HCDG_03431 HCDG_03431 HCDG_03470 HCDG_03470 HCDG_03519 HCDG_03519 HCDG_03532 HCDG_03532 HCDG_03547 HCDG_03547 HCDG_03605 HCDG_03605 HCDG_03657 HCDG_03657 HCDG_03734 HCDG_03734 HCDG_04055 HCDG_04055 HCDG_04058 HCDG_04058 HCDG_04158 HCDG_04158 HCDG_04180 HCDG_04180 HCDG_04181 HCDG_04181 HCDG_04219 HCDG_04219 HCDG_04272 HCDG_04272 HCDG_04298 HCDG_04298 HCDG_04327 HCDG_04327 HCDG_04425 HCDG_04425 HCDG_04434 HCDG_04434 HCDG_04683 HCDG_04683 HCDG_04476 HCDG_04476 HCDG_04482 HCDG_04482 HCDG_04763 HCDG_04763 SLX1 SLX1 HCDG_04888 HCDG_04888 HCDG_04922 HCDG_04922 HCDG_04924 HCDG_04924 HCDG_05002 HCDG_05002 HCDG_04530 HCDG_04530 HCDG_04549 HCDG_04549 HCDG_04550 HCDG_04550 HCDG_04600 HCDG_04600 HCDG_04674 HCDG_04674 HCDG_05626 HCDG_05626 HCDG_05597 HCDG_05597 HCDG_05547 HCDG_05547 HCDG_05524 HCDG_05524 HCDG_05207 HCDG_05207 HCDG_05181 HCDG_05181 HCDG_05173 HCDG_05173 HCDG_05104 HCDG_05104 HCDG_05018 HCDG_05018 HCDG_05378 HCDG_05378 HCDG_05269 HCDG_05269 HCDG_05258 HCDG_05258 HCDG_04693 HCDG_04693 HCDG_09426 HCDG_09426 HCDG_09263 HCDG_09263 HCDG_09248 HCDG_09248 HCDG_09244 HCDG_09244 HCDG_09107 HCDG_09107 HCDG_09013 HCDG_09013 HCDG_09000 HCDG_09000 HCDG_08967 HCDG_08967 HCDG_08935 HCDG_08935 HCDG_08601 HCDG_08601 HCDG_08579 HCDG_08579 HCDG_08553 HCDG_08553 HCDG_08440 HCDG_08440 HCDG_08419 HCDG_08419 HCDG_08788 HCDG_08788 HCDG_08730 HCDG_08730 HCDG_08729 HCDG_08729 HCDG_08698 HCDG_08698 FEN1 FEN1 HCDG_08398 HCDG_08398 HCDG_08381 HCDG_08381 HCDG_08274 HCDG_08274 HCDG_08256 HCDG_08256 HCDG_08255 HCDG_08255 HCDG_08245 HCDG_08245 HCDG_08208 HCDG_08208 HCDG_08181 HCDG_08181 HCDG_08138 HCDG_08138 HCDG_08112 HCDG_08112 HCDG_08064 HCDG_08064 HCDG_08057 HCDG_08057 HCDG_08026 HCDG_08026 HCDG_08015 HCDG_08015 HCDG_08000 HCDG_08000 HCDG_07961 HCDG_07961 HCDG_07885 HCDG_07885 HCDG_07798 HCDG_07798 HCDG_07729 HCDG_07729 HCDG_07712 HCDG_07712 HCDG_07644 HCDG_07644 HCDG_07462 HCDG_07462 HCDG_07461 HCDG_07461 HCDG_07445 HCDG_07445 HCDG_07443 HCDG_07443 HCDG_07428 HCDG_07428 HCDG_07321 HCDG_07321 HCDG_07280 HCDG_07280 HCDG_07270 HCDG_07270 HCDG_07227 HCDG_07227 HCDG_07128 HCDG_07128 HCDG_07540 HCDG_07540 HCDG_07529 HCDG_07529 HCDG_07076 HCDG_07076 HCDG_07040 HCDG_07040 HCDG_06976 HCDG_06976 HCDG_06902 HCDG_06902 HCDG_06901 HCDG_06901 HCDG_06882 HCDG_06882 HCDG_06860 HCDG_06860 HCDG_06853 HCDG_06853 HCDG_06843 HCDG_06843 HCDG_06781 HCDG_06781 HCDG_06775 HCDG_06775 HCDG_06774 HCDG_06774 HCDG_06770 HCDG_06770 HCDG_06730 HCDG_06730 PIF1 PIF1 HCDG_06587 HCDG_06587 HCDG_06497 HCDG_06497 HCDG_06490 HCDG_06490 HCDG_06482 HCDG_06482 HCDG_06434 HCDG_06434 HCDG_06433 HCDG_06433 HCDG_06409 HCDG_06409 HCDG_06340 HCDG_06340 HCDG_06328 HCDG_06328 HCDG_06293 HCDG_06293 HCDG_06104 HCDG_06104 HCDG_06086 HCDG_06086 HCDG_06078 HCDG_06078 HCDG_06048 HCDG_06048 HCDG_06041 HCDG_06041 HCDG_05993 HCDG_05993 HCDG_05959 HCDG_05959 HCDG_05953 HCDG_05953 HCDG_05932 HCDG_05932 HCDG_05925 HCDG_05925 HCDG_05915 HCDG_05915 HCDG_05913 HCDG_05913 HCDG_05839 HCDG_05839 HCDG_05838 HCDG_05838 HCDG_06273 HCDG_06273 HCDG_06242 HCDG_06242 HCDG_06236 HCDG_06236 HCDG_06229 HCDG_06229 HCDG_06228 HCDG_06228 HCDG_06197 HCDG_06197 HCDG_06157 HCDG_06157 HCDG_05806 HCDG_05806 HCDG_05777 HCDG_05777 HCDG_05757 HCDG_05757 HCDG_03183 HCDG_03183 HCDG_03205 HCDG_03205 HCDG_03248 HCDG_03248 HCDG_03249 HCDG_03249 HCDG_03318 HCDG_03318 HCDG_00508 HCDG_00508 HCDG_00528 HCDG_00528 HCDG_00583 HCDG_00583 HCDG_00723 HCDG_00723 HCDG_00763 HCDG_00763 HCDG_00764 HCDG_00764 HCDG_00765 HCDG_00765 HCDG_00876 HCDG_00876 HCDG_00895 HCDG_00895 HCDG_00900 HCDG_00900 HCDG_00967 HCDG_00967 HCDG_00968 HCDG_00968 HCDG_00969 HCDG_00969 HCDG_01079 HCDG_01079 HCDG_03139 HCDG_03139 HCDG_03061 HCDG_03061 HCDG_03052 HCDG_03052 HCDG_03044 HCDG_03044 HCDG_03043 HCDG_03043 SLX4 SLX4 HCDG_02921 HCDG_02921 HCDG_02882 HCDG_02882 HCDG_02872 HCDG_02872 HCDG_02853 HCDG_02853 HCDG_02812 HCDG_02812 HCDG_02809 HCDG_02809 HCDG_02798 HCDG_02798 HCDG_02793 HCDG_02793 HCDG_02679 HCDG_02679 HCDG_02665 HCDG_02665 HCDG_02623 HCDG_02623 HCDG_02576 HCDG_02576 HCDG_02573 HCDG_02573 HCDG_02455 HCDG_02455 HCDG_01669 HCDG_01669 HCDG_01652 HCDG_01652 HCDG_01593 HCDG_01593 HCDG_01592 HCDG_01592 HCDG_01574 HCDG_01574 HCDG_01539 HCDG_01539 HCDG_01510 HCDG_01510 HCDG_01495 HCDG_01495 HCDG_02438 HCDG_02438 HCDG_02311 HCDG_02311 HCDG_02270 HCDG_02270 HCDG_02210 HCDG_02210 HCDG_02195 HCDG_02195 HCDG_02191 HCDG_02191 HCDG_02168 HCDG_02168 HCDG_02167 HCDG_02167 HCDG_02116 HCDG_02116 HCDG_02076 HCDG_02076 HCDG_02027 HCDG_02027 HCDG_02018 HCDG_02018 HCDG_01961 HCDG_01961 HCDG_01905 HCDG_01905 HCDG_01901 HCDG_01901 HCDG_01760 HCDG_01760 HCDG_01727 HCDG_01727 HCDG_00463 HCDG_00463 HCDG_00406 HCDG_00406 HCDG_00386 HCDG_00386 HCDG_00385 HCDG_00385 HCDG_00382 HCDG_00382 HCDG_00369 HCDG_00369 HCDG_00336 HCDG_00336 HCDG_00335 HCDG_00335 HCDG_00270 HCDG_00270 HCDG_00230 HCDG_00230 HCDG_00217 HCDG_00217 HCDG_00199 HCDG_00199 HCDG_01426 HCDG_01426 HCDG_01386 HCDG_01386 HCDG_01369 HCDG_01369 HCDG_00064 HCDG_00064 HCDG_00050 HCDG_00050 NTH1 NTH1 HCDG_01197 HCDG_01197
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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HCDG_00014DNA replication factor C subunit Rfc3. (345 aa)
HCDG_01177RECA_2 domain-containing protein. (423 aa)
UNG1Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (886 aa)
HCDG_03831RecA family ATPase Rhp57. (701 aa)
HCDG_03857Cell cycle checkpoint protein rad17. (967 aa)
HCDG_03888Cell wall protein. (251 aa)
HCDG_03938Uncharacterized protein. (772 aa)
HCDG_03956DsDNA-dependent ATPase. (974 aa)
HCDG_03980GRF zinc finger domain-containing protein. (432 aa)
HCDG_04004Uncharacterized protein. (519 aa)
HCDG_03350DNA mismatch repair protein. (1114 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (698 aa)
HCDG_033773'-5' exonuclease/helicase. (947 aa)
HCDG_03430DNA repair protein RAD7. (638 aa)
HCDG_03431DNA repair protein RAD16. (848 aa)
HCDG_03470Histidine triad nucleotide-binding protein. (281 aa)
HCDG_03519DNA polymerase. (1053 aa)
HCDG_03532Postreplication repair E3 ubiquitin-protein ligase rad18. (420 aa)
HCDG_03547Uncharacterized protein. (1552 aa)
HCDG_03605DNA ligase. (844 aa)
HCDG_03657Crossover junction endonuclease mus81. (650 aa)
HCDG_03734DNA repair helicase RAD3. (773 aa)
HCDG_04055Uncharacterized protein. (387 aa)
HCDG_04058SP-RING-type domain-containing protein. (506 aa)
HCDG_04158Nitrilase. (883 aa)
HCDG_04180Uncharacterized protein. (110 aa)
HCDG_04181Uncharacterized protein. (811 aa)
HCDG_04219SNF2 family helicase/ATPase. (1028 aa)
HCDG_04272Oxidoreductase. (413 aa)
HCDG_04298DNA lyase. (528 aa)
HCDG_04327Uncharacterized protein. (669 aa)
HCDG_04425Uncharacterized protein. (300 aa)
HCDG_04434DNA mismatch repair protein. (1515 aa)
HCDG_04683DNA helicase; Belongs to the MCM family. (718 aa)
HCDG_04476DNA helicase; Belongs to the MCM family. (857 aa)
HCDG_04482Thermotolerance protein. (1275 aa)
HCDG_04763DNA repair helicase RAD25. (1379 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (421 aa)
HCDG_04888Meiosis-specific topoisomerase Spo11. (380 aa)
HCDG_04922Zn(2)-C6 fungal-type domain-containing protein. (645 aa)
HCDG_04924Uncharacterized protein. (181 aa)
HCDG_05002Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (471 aa)
HCDG_04530Meiotic recombination protein; Belongs to the MRE11/RAD32 family. (503 aa)
HCDG_04549Uncharacterized protein. (111 aa)
HCDG_04550RNA binding domain-containing protein. (162 aa)
HCDG_04600ERCC4 domain-containing protein. (197 aa)
HCDG_04674ATP-dependent DNA ligase domain-containing protein. (1086 aa)
HCDG_05626Chromatin remodeling complex subunit; Belongs to the actin family. (1761 aa)
HCDG_05597DEAD/DEAH box helicase. (1198 aa)
HCDG_05547Serine/threonine protein kinase. (631 aa)
HCDG_05524DNA polymerase kappa. (604 aa)
HCDG_05207DNA repair protein RAD14. (334 aa)
HCDG_05181AGC kinase. (590 aa)
HCDG_05173Activator 1 37 kDa subunit. (354 aa)
HCDG_05104General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (505 aa)
HCDG_05018RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (467 aa)
HCDG_05378TAM domain methyltransferase. (248 aa)
HCDG_05269BRCT domain-containing protein. (269 aa)
HCDG_05258Ubiquitin homeostasis protein lub1. (788 aa)
HCDG_04693Histone acetylase complex subunit Paf400; Belongs to the PI3/PI4-kinase family. (3750 aa)
HCDG_09426Fumarate hydratase class II. (567 aa)
HCDG_09263Ku70. (573 aa)
HCDG_09248Pre-mRNA-splicing factor cwc24. (826 aa)
HCDG_09244Uncharacterized protein. (188 aa)
HCDG_09107DNA excision repair protein Rad2. (1159 aa)
HCDG_09013ENDO3c domain-containing protein. (299 aa)
HCDG_09000DNA repair protein RAD1. (866 aa)
HCDG_08967Pregnancy upregulated non-ubiquitously expressed CaM kinase. (653 aa)
HCDG_08935Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (156 aa)
HCDG_08601Nucleosome binding protein. (102 aa)
HCDG_08579Rnapii degradation factor def1. (884 aa)
HCDG_08553MAGE domain-containing protein. (336 aa)
HCDG_08440Serine/threonine protein kinase. (1106 aa)
HCDG_08419DNA cross-link repair protein pso2/snm1. (841 aa)
HCDG_08788YEATS family protein. (252 aa)
HCDG_08730Uncharacterized protein. (328 aa)
HCDG_08729Chromosome segregation protein. (849 aa)
HCDG_08698Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (341 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
HCDG_08398FACT complex subunit spt16. (1023 aa)
HCDG_08381Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (541 aa)
HCDG_08274DNA ATP-dependent helicase. (1764 aa)
HCDG_08256RSC complex subunit. (518 aa)
HCDG_08255RSC complex subunit. (625 aa)
HCDG_08245Methylated-DNA-protein-cysteine methyltransferase. (490 aa)
HCDG_08208SNF2 family helicase/ATPase. (1762 aa)
HCDG_08181DUF1337 domain-containing protein. (144 aa)
HCDG_08138RNA polymerase II transcription factor B subunit 5. (104 aa)
HCDG_08112Rad51 family DNA repair protein. (455 aa)
HCDG_08064Plus3 domain-containing protein. (638 aa)
HCDG_080576-O-methylguanine DNA methyltransferase. (197 aa)
HCDG_08026Exonuclease. (829 aa)
HCDG_08015DNA repair protein RAD18. (1148 aa)
HCDG_08000Histone H2A; Belongs to the histone H2A family. (134 aa)
HCDG_07961AAA domain-containing protein. (1230 aa)
HCDG_07885Uncharacterized protein. (98 aa)
HCDG_07798DNA replication initiation factor Cdc45. (846 aa)
HCDG_07729Uncharacterized protein. (304 aa)
HCDG_07712Uncharacterized protein. (218 aa)
HCDG_07644Uncharacterized protein. (103 aa)
HCDG_07462DNA replication licensing factor mcm2. (252 aa)
HCDG_07461DNA replication licensing factor mcm2; Belongs to the MCM family. (542 aa)
HCDG_07445Uncharacterized protein. (100 aa)
HCDG_07443DNA damage-binding protein 1a. (1134 aa)
HCDG_07428Single-stranded DNA binding protein p30 subunit. (265 aa)
HCDG_07321Mitotic spindle checkpoint protein. (357 aa)
HCDG_07280Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (279 aa)
HCDG_07270Sister chromatid cohesion protein. (1772 aa)
HCDG_07227DNA helicase; Belongs to the MCM family. (965 aa)
HCDG_07128RNA polymerase II transcription factor B subunit 4. (412 aa)
HCDG_07540Endo/exonuclease/phosphatase domain-containing protein. (636 aa)
HCDG_07529DNA polymerase. (1503 aa)
HCDG_07076Poly [ADP-ribose] polymerase. (595 aa)
HCDG_07040DNA repair/transcription protein. (1023 aa)
HCDG_06976MutS2 protein. (999 aa)
HCDG_06902DNA mismatch repair protein. (449 aa)
HCDG_06901Uncharacterized protein. (187 aa)
HCDG_06882WD40 domain-containing protein. (793 aa)
HCDG_06860Serine/threonine protein phosphatase PP-X isozyme 1. (427 aa)
HCDG_06853DNA ligase. (940 aa)
HCDG_06843Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (530 aa)
HCDG_06781DNA repair protein rad5. (1034 aa)
HCDG_06775Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2777 aa)
HCDG_06774Nuclear pore complex subunit Nup192; Belongs to the cullin family. (2454 aa)
HCDG_06770SsDNA binding protein Ssb3. (117 aa)
HCDG_06730Ubiquitin-protein ligase E4. (476 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (794 aa)
HCDG_06587Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (557 aa)
HCDG_06497Replication factor C subunit 1. (1071 aa)
HCDG_06490Activator 1 38 kDa subunit. (325 aa)
HCDG_06482Uncharacterized protein. (278 aa)
HCDG_06434Uncharacterized protein. (1890 aa)
HCDG_06433PAPA-1 domain-containing protein. (406 aa)
HCDG_06409DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1111 aa)
HCDG_06340DNA helicase; Belongs to the MCM family. (1758 aa)
HCDG_06328Double-strand-break repair protein rad21. (600 aa)
HCDG_06293Uncharacterized protein. (248 aa)
HCDG_06104DNA replication ATP-dependent helicase dna2. (1609 aa)
HCDG_06086Ubiquitin-conjugating enzyme. (135 aa)
HCDG_06078Formamidopyrimidine-DNA glycosylase lyase mutM. (383 aa)
HCDG_06048RNA polymerase II transcription factor. (644 aa)
HCDG_06041DNA replication complex GINS protein psf3. (159 aa)
HCDG_05993Proteasome activator subunit 4. (743 aa)
HCDG_05959DNA polymerase iota. (730 aa)
HCDG_05953DNA replication ATPase. (547 aa)
HCDG_05932RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. (459 aa)
HCDG_05925Histone acetylase complex subunit. (331 aa)
HCDG_05915NET domain-containing protein. (253 aa)
HCDG_05913PSF1 domain-containing protein. (277 aa)
HCDG_05839Mismatch repair protein. (627 aa)
HCDG_05838Uncharacterized protein. (112 aa)
HCDG_06273Tyrosyl-DNA phosphodiesterase. (685 aa)
HCDG_06242DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (450 aa)
HCDG_06236DNA polymerase. (1458 aa)
HCDG_06229DNA repair and recombination protein RAD26. (102 aa)
HCDG_06228DNA repair and recombination protein RAD26. (819 aa)
HCDG_06197Mitochondrial genome maintenance protein MGM101. (303 aa)
HCDG_06157Uncharacterized protein. (251 aa)
HCDG_05806Tyrosyl-DNA phosphodiesterase domain-containing protein. (183 aa)
HCDG_05777Enhancer of polycomb-like protein. (588 aa)
HCDG_05757Uncharacterized protein. (320 aa)
HCDG_03183DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (504 aa)
HCDG_03205DNA polymerase I. (941 aa)
HCDG_03248Vezatin domain-containing protein. (314 aa)
HCDG_03249Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (548 aa)
HCDG_03318DNA polymerase epsilon subunit B. (644 aa)
HCDG_00508Hydrolase. (319 aa)
HCDG_00528Uncharacterized protein. (119 aa)
HCDG_00583Uncharacterized protein. (150 aa)
HCDG_00723DNA mismatch repair protein. (820 aa)
HCDG_00763Uncharacterized protein. (200 aa)
HCDG_00764DNA mismatch repair protein. (312 aa)
HCDG_00765DNA mismatch repair protein. (519 aa)
HCDG_00876Uncharacterized protein. (747 aa)
HCDG_00895Uncharacterized protein. (468 aa)
HCDG_00900BRCT domain-containing protein. (857 aa)
HCDG_00967DNA repair protein RAD50. (1421 aa)
HCDG_00968DNA repair protein RAD1. (401 aa)
HCDG_00969Uncharacterized protein. (77 aa)
HCDG_01079CDK-activating kinase assembly factor MAT1. (369 aa)
HCDG_03139Helicase C-terminal domain-containing protein. (1055 aa)
HCDG_03061Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (820 aa)
HCDG_030528-oxoguanine DNA glycosylase. (422 aa)
HCDG_03044FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (332 aa)
HCDG_03043FACT complex subunit pob3. (152 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (847 aa)
HCDG_02921C6 zinc finger protein. (851 aa)
HCDG_02882DNA excision repair protein. (979 aa)
HCDG_02872Chromatin modification-related protein. (444 aa)
HCDG_02853FYVE zinc finger protein. (679 aa)
HCDG_02812Uncharacterized protein. (122 aa)
HCDG_02809DNA repair protein RAD51. (249 aa)
HCDG_02798Polymerase. (717 aa)
HCDG_02793Sir2 family histone deacetylase Hst4. (574 aa)
HCDG_02679Serine/threonine protein kinase. (501 aa)
HCDG_02665RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (485 aa)
HCDG_02623Proteasome regulatory particle subunit Rpt4. (371 aa)
HCDG_02576SNF2 family helicase/ATPase. (1151 aa)
HCDG_02573Uncharacterized protein. (594 aa)
HCDG_02455WD40 domain-containing protein. (487 aa)
HCDG_01669Polynucleotide kinase. (476 aa)
HCDG_01652DNA methyltransferase. (613 aa)
HCDG_01593RAD52 DNA repair protein RADC. (276 aa)
HCDG_01592RAD52 DNA repair protein RADC. (204 aa)
HCDG_01574DNA-3-methyladenine glycosylase. (399 aa)
HCDG_01539DNA mismatch repair protein. (1003 aa)
HCDG_01510Mating-type switching protein swi10. (361 aa)
HCDG_01495RSC complex subunit Sfh1. (526 aa)
HCDG_02438Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
HCDG_02311DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (941 aa)
HCDG_02270DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2111 aa)
HCDG_02210Casein kinase I; Belongs to the protein kinase superfamily. (401 aa)
HCDG_02195ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. (723 aa)
HCDG_02191DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (630 aa)
HCDG_02168Acetamidase/formamidase. (180 aa)
HCDG_02167Acetamidase/formamidase. (324 aa)
HCDG_02116DNA repair and recombination protein RAD54. (649 aa)
HCDG_02076Uncharacterized protein. (412 aa)
HCDG_02027Uracil DNA glycosylase superfamily protein. (301 aa)
HCDG_02018RING-13 protein. (1188 aa)
HCDG_01961Checkpoint protein; Belongs to the HUS1 family. (364 aa)
HCDG_01905Rad21/Rec8 N terminal domain-containing protein. (713 aa)
HCDG_01901Spr18 protein. (1160 aa)
HCDG_01760UV-damage endonuclease. (704 aa)
HCDG_01727DNA polymerase delta subunit 4. (214 aa)
HCDG_00463DNA repair protein Nse1. (325 aa)
HCDG_00406XPG_I_2 domain-containing protein. (756 aa)
HCDG_00386Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1490 aa)
HCDG_00385Uncharacterized protein. (711 aa)
HCDG_00382Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (346 aa)
HCDG_0036926S protease regulatory subunit 8; Belongs to the AAA ATPase family. (389 aa)
HCDG_00336Topoisomerase 1-associated factor 1. (810 aa)
HCDG_00335Topoisomerase I. (109 aa)
HCDG_00270MYB and HSA domain-containing protein. (1453 aa)
HCDG_00230Uncharacterized protein. (238 aa)
HCDG_00217NUDIX domain-containing protein. (295 aa)
HCDG_00199DNA replication factor C subunit Rfc2. (394 aa)
HCDG_01426DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (129 aa)
HCDG_01386High-affinity nickel transporter. (694 aa)
HCDG_01369DNA ligase. (899 aa)
HCDG_00064Meiotic recombination protein; Belongs to the RecA family. (381 aa)
HCDG_00050Uncharacterized protein. (377 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (533 aa)
HCDG_01197Rad4 family protein. (907 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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