80 items (Histoplasma capsulatum H143) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCDG_00803	Pantetheine-phosphate adenylyltransferase. (418 aa)
	HCDG_01145	Galactose-1-phosphate uridylyltransferase. (200 aa)
	HCDG_00052	RNA polymerase I subunit Rpa43. (464 aa)
	HCDG_00063	UDP-N-acetylglucosamine pyrophosphorylase. (282 aa)
	HCDG_01273	Uncharacterized protein. (196 aa)
	HCDG_01274	RNA-dependent RNA polymerase. (396 aa)
	HCDG_01275	Uncharacterized protein. (155 aa)
	HCDG_01368	mRNA capping enzyme alpha subunit. (368 aa)
	HCDG_01386	High-affinity nickel transporter. (694 aa)
	HCDG_00325	DNA polymerase delta small subunit. (565 aa)
	HCDG_02140	Translation initiation factor eIF-2B epsilon subunit. (723 aa)
	HCDG_02270	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2111 aa)
	HCDG_02296	APH domain-containing protein. (573 aa)
	HCDG_01468	Phosphoethanolamine. (441 aa)
	HCDG_01565	Uncharacterized protein. (314 aa)
	HCDG_01640	Uncharacterized protein. (400 aa)
	HCDG_01645	Cytidylyltransferase. (380 aa)
	HCDG_01680	Lipoyltransferase and lipoate-protein ligase. (179 aa)
	HCDG_02710	Uncharacterized protein. (601 aa)
	HCDG_02798	Polymerase. (717 aa)
	HCDG_02856	Uncharacterized protein. (168 aa)
	HCDG_02865	UTP--glucose-1-phosphate uridylyltransferase. (524 aa)
	HCDG_02871	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (363 aa)
	HCDG_03031	DNA-directed RNA polymerase I and III. (380 aa)
	HCDG_03183	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (504 aa)
	HCDG_03215	DNA-directed RNA polymerase I. (159 aa)
	HCDG_03861	Uncharacterized protein. (152 aa)
	HCDG_03862	Uncharacterized protein. (278 aa)
	HCDG_04003	RNA polymerase subunit. (236 aa)
	HCDG_04010	MMP37-like protein. (424 aa)
	HCDG_03422	DNA-directed RNA polymerase II. (168 aa)
	HCDG_03519	DNA polymerase. (1053 aa)
	HCDG_03528	Uncharacterized protein. (428 aa)
	HCDG_03529	Poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (639 aa)
	HCDG_03733	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1676 aa)
	HCDG_04086	GDP-mannose pyrophosphorylase A. (437 aa)
	HCDG_04126	Nicotinamide mononucleotide adenylyl transferase. (253 aa)
	HCDG_04322	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1242 aa)
	HCDG_04348	RNA polymerase II subunit 3. (333 aa)
	HCDG_04900	RNA-dependent RNA polymerase. (1317 aa)
	HCDG_05064	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1227 aa)
	HCDG_05524	DNA polymerase kappa. (604 aa)
	HCDG_05669	Poly(A) RNA polymerase cid14. (680 aa)
	HCDG_05767	RNA-dependent RNA polymerase. (1240 aa)
	HCDG_05774	DNA-directed RNA polymerase I and III. (137 aa)
	HCDG_06236	DNA polymerase. (1458 aa)
	HCDG_05959	DNA polymerase iota. (730 aa)
	HCDG_06031	Mannose-1-phosphate guanyltransferase. (300 aa)
	HCDG_06073	Metallothionein-I gene transcription activator. (75 aa)
	HCDG_06351	Translation initiation protein Sua5. (473 aa)
	HCDG_06409	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1111 aa)
	HCDG_06778	DNA polymerase gamma. (1084 aa)
	NCS2	Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (349 aa)
	HCDG_06927	DNA-directed RNA polymerase III. (202 aa)
	HCDG_07000	Bis(5'-nucleosyl)-tetraphosphatase. (350 aa)
	HCDG_07529	DNA polymerase. (1503 aa)
	MET3	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
	HCDG_07321	Mitotic spindle checkpoint protein. (357 aa)
	HCDG_07359	DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1265 aa)
	HCDG_07360	Uncharacterized protein. (368 aa)
	HCDG_07373	Molybdenum cofactor biosynthesis protein. (227 aa)
	HCDG_07374	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (467 aa)
	HCDG_07429	FAD synthetase. (323 aa)
	HCDG_07434	Uncharacterized protein. (554 aa)
	HCDG_07810	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (493 aa)
	HCDG_07824	DUF455 domain-containing protein. (1256 aa)
	HCDG_07873	tRNA(His) guanylyltransferase. (292 aa)
	HCDG_07875	DNA-directed RNA polymerase II. (668 aa)
	HCDG_07876	Ribosomal polymerase B1. (132 aa)
	HCDG_08020	DNA-directed RNA polymerase. (115 aa)
	HCDG_08024	DNA primase; Belongs to the eukaryotic-type primase small subunit family. (567 aa)
	HCDG_08119	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1333 aa)
	HCDG_08300	Cholinephosphate cytidylyltransferase. (416 aa)
	HCDG_08693	YdiU domain-containing protein. (620 aa)
	HCDG_09039	Molybdenum cofactor biosynthetic protein. (302 aa)
	HCDG_09040	Molybdenum cofactor biosynthetic protein. (182 aa)
	HCDG_09229	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (259 aa)
	HCDG_09271	PAP/25A associated domain family. (839 aa)
	HCDG_09299	APH domain-containing protein. (421 aa)
	HCDG_09521	VEG136 protein. (308 aa)

Your Current Organism:

Histoplasma capsulatum H143

NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCDG_00052	HCDG_02871	C6H3P1	C6H9J0	RNA polymerase I subunit Rpa43.	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.	0.532
HCDG_00052	HCDG_03031	C6H3P1	C6HA00	RNA polymerase I subunit Rpa43.	DNA-directed RNA polymerase I and III.	0.999
HCDG_00052	HCDG_03215	C6H3P1	C6HAI4	RNA polymerase I subunit Rpa43.	DNA-directed RNA polymerase I.	0.999
HCDG_00052	HCDG_03733	C6H3P1	C6HCI4	RNA polymerase I subunit Rpa43.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
HCDG_00052	HCDG_04003	C6H3P1	C6HBC1	RNA polymerase I subunit Rpa43.	RNA polymerase subunit.	0.999
HCDG_00052	HCDG_04322	C6H3P1	C6HDP1	RNA polymerase I subunit Rpa43.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
HCDG_00052	HCDG_04348	C6H3P1	C6HDR7	RNA polymerase I subunit Rpa43.	RNA polymerase II subunit 3.	0.986
HCDG_00052	HCDG_05064	C6H3P1	C6HGH3	RNA polymerase I subunit Rpa43.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.984
HCDG_00052	HCDG_05774	C6H3P1	C6HHU3	RNA polymerase I subunit Rpa43.	DNA-directed RNA polymerase I and III.	0.998
HCDG_00052	HCDG_06073	C6H3P1	C6HJ39	RNA polymerase I subunit Rpa43.	Metallothionein-I gene transcription activator.	0.999
HCDG_00052	HCDG_06927	C6H3P1	C6HL46	RNA polymerase I subunit Rpa43.	DNA-directed RNA polymerase III.	0.563
HCDG_00052	HCDG_08020	C6H3P1	C6HP89	RNA polymerase I subunit Rpa43.	DNA-directed RNA polymerase.	0.999
HCDG_00052	HCDG_08119	C6H3P1	C6HPI8	RNA polymerase I subunit Rpa43.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.983
HCDG_00052	HCDG_09229	C6H3P1	C6HSP8	RNA polymerase I subunit Rpa43.	DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.	0.462
HCDG_00063	HCDG_01145	C6H3Q2	C6H363	UDP-N-acetylglucosamine pyrophosphorylase.	Galactose-1-phosphate uridylyltransferase.	0.751
HCDG_00063	HCDG_02865	C6H3Q2	C6H9I4	UDP-N-acetylglucosamine pyrophosphorylase.	UTP--glucose-1-phosphate uridylyltransferase.	0.563
HCDG_00325	HCDG_01386	C6H504	C6H4E7	DNA polymerase delta small subunit.	High-affinity nickel transporter.	0.595
HCDG_00325	HCDG_02270	C6H504	C6H769	DNA polymerase delta small subunit.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.974
HCDG_00325	HCDG_02798	C6H504	C6H9B7	DNA polymerase delta small subunit.	Polymerase.	0.662
HCDG_00325	HCDG_03183	C6H504	C6HAF2	DNA polymerase delta small subunit.	DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.	0.965