STRINGSTRING
HCDG_08026 HCDG_08026 HCDG_08960 HCDG_08960 HCDG_08959 HCDG_08959 HCDG_08528 HCDG_08528 HCDG_08698 HCDG_08698 FEN1 FEN1 HCDG_00551 HCDG_00551 HCDG_00823 HCDG_00823 HCDG_00447 HCDG_00447 HCDG_01733 HCDG_01733 HCDG_01885 HCDG_01885 HCDG_02234 HCDG_02234 HCDG_02573 HCDG_02573 SLX4 SLX4 HCDG_03061 HCDG_03061 HCDG_03938 HCDG_03938 HCDG_03406 HCDG_03406 SLX1 SLX1 HCDG_04607 HCDG_04607 HCDG_04622 HCDG_04622 HCDG_05291 HCDG_05291 HCDG_05122 HCDG_05122 HCDG_05162 HCDG_05162 HCDG_06103 HCDG_06103 HCDG_06104 HCDG_06104 HCDG_06620 HCDG_06620 HCDG_06621 HCDG_06621 HCDG_06639 HCDG_06639 HCDG_06829 HCDG_06829 HCDG_06890 HCDG_06890 HCDG_06891 HCDG_06891 HCDG_06983 HCDG_06983 HCDG_07705 HCDG_07705
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_08026Exonuclease. (829 aa)
HCDG_08960Ribonuclease P complex subunit Pop1. (393 aa)
HCDG_08959Ribonuclease P complex subunit Pop1. (387 aa)
HCDG_08528Eukaryotic translation initiation factor 2c. (902 aa)
HCDG_08698Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (341 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
HCDG_00551Uncharacterized protein. (458 aa)
HCDG_00823QDE2 protein. (1038 aa)
HCDG_00447Piwi domain-containing protein. (168 aa)
HCDG_01733Uncharacterized protein. (95 aa)
HCDG_01885RNAse P Rpr2/Rpp21 subunit domain-containing protein. (200 aa)
HCDG_02234Uncharacterized protein. (235 aa)
HCDG_02573Uncharacterized protein. (594 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (847 aa)
HCDG_03061Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (820 aa)
HCDG_03938Uncharacterized protein. (772 aa)
HCDG_03406RNase III domain-containing protein. (141 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (421 aa)
HCDG_04607Uncharacterized protein. (170 aa)
HCDG_04622RNA lariat debranching enzyme. (752 aa)
HCDG_0529160S ribosomal protein L3. (394 aa)
HCDG_05122RNase3 domain-containing protein. (380 aa)
HCDG_05162HLA class III protein Dom3z. (344 aa)
HCDG_06103Uncharacterized protein. (308 aa)
HCDG_06104DNA replication ATP-dependent helicase dna2. (1609 aa)
HCDG_06620Dicer-like protein. (800 aa)
HCDG_06621Dicer-like protein. (341 aa)
HCDG_06639Uncharacterized protein. (88 aa)
HCDG_06829XPG N-terminal domain-containing protein. (722 aa)
HCDG_06890ATP-dependent helicase DCL1. (495 aa)
HCDG_06891ATP-dependent helicase DCL1. (896 aa)
HCDG_06983Ribonuclease P protein subunit p30. (316 aa)
HCDG_07705Ribonuclease Z. (1123 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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