13 items (Histoplasma capsulatum H143) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	HCDG_07462	DNA replication licensing factor mcm2. (252 aa)
	HCDG_07227	DNA helicase; Belongs to the MCM family. (965 aa)
	HCDG_07461	DNA replication licensing factor mcm2; Belongs to the MCM family. (542 aa)
	HCDG_06340	DNA helicase; Belongs to the MCM family. (1758 aa)
	HCDG_06041	DNA replication complex GINS protein psf3. (159 aa)
	HCDG_08065	MRC1 domain-containing protein. (1491 aa)
	HCDG_04476	DNA helicase; Belongs to the MCM family. (857 aa)
	HCDG_05913	PSF1 domain-containing protein. (277 aa)
	HCDG_04683	DNA helicase; Belongs to the MCM family. (718 aa)
	HCDG_00550	Cell division cycle protein. (803 aa)
	HCDG_03043	FACT complex subunit pob3. (152 aa)
	HCDG_03044	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (332 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (698 aa)

Your Current Organism:

Histoplasma capsulatum H143

NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCDG_00550	HCDG_04476	C6H1G8	C6HE45	Cell division cycle protein.	DNA helicase; Belongs to the MCM family.	0.996
HCDG_00550	HCDG_04683	C6H1G8	C6HFG0	Cell division cycle protein.	DNA helicase; Belongs to the MCM family.	0.996
HCDG_00550	HCDG_05913	C6H1G8	C6HIM9	Cell division cycle protein.	PSF1 domain-containing protein.	0.825
HCDG_00550	HCDG_06041	C6H1G8	C6HJ07	Cell division cycle protein.	DNA replication complex GINS protein psf3.	0.761
HCDG_00550	HCDG_06340	C6H1G8	C6HJF9	Cell division cycle protein.	DNA helicase; Belongs to the MCM family.	0.998
HCDG_00550	HCDG_07227	C6H1G8	C6HMB1	Cell division cycle protein.	DNA helicase; Belongs to the MCM family.	0.998
HCDG_00550	HCDG_07461	C6H1G8	C6HMZ5	Cell division cycle protein.	DNA replication licensing factor mcm2; Belongs to the MCM family.	0.987
HCDG_00550	HCDG_07462	C6H1G8	C6HMZ6	Cell division cycle protein.	DNA replication licensing factor mcm2.	0.987
HCDG_00550	HCDG_08065	C6H1G8	C6HPD4	Cell division cycle protein.	MRC1 domain-containing protein.	0.690
HCDG_00550	MCM7	C6H1G8	C6HBG2	Cell division cycle protein.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.998
HCDG_03043	HCDG_03044	C6HA12	C6HA13	FACT complex subunit pob3.	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	0.931
HCDG_03043	HCDG_04476	C6HA12	C6HE45	FACT complex subunit pob3.	DNA helicase; Belongs to the MCM family.	0.459
HCDG_03043	HCDG_04683	C6HA12	C6HFG0	FACT complex subunit pob3.	DNA helicase; Belongs to the MCM family.	0.627
HCDG_03043	HCDG_06340	C6HA12	C6HJF9	FACT complex subunit pob3.	DNA helicase; Belongs to the MCM family.	0.873
HCDG_03043	HCDG_07227	C6HA12	C6HMB1	FACT complex subunit pob3.	DNA helicase; Belongs to the MCM family.	0.604
HCDG_03043	HCDG_07461	C6HA12	C6HMZ5	FACT complex subunit pob3.	DNA replication licensing factor mcm2; Belongs to the MCM family.	0.681
HCDG_03043	HCDG_07462	C6HA12	C6HMZ6	FACT complex subunit pob3.	DNA replication licensing factor mcm2.	0.681
HCDG_03043	MCM7	C6HA12	C6HBG2	FACT complex subunit pob3.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.622
HCDG_03044	HCDG_03043	C6HA13	C6HA12	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	FACT complex subunit pob3.	0.931
HCDG_03044	HCDG_04476	C6HA13	C6HE45	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]	DNA helicase; Belongs to the MCM family.	0.459