71 items (Histoplasma capsulatum H143) - STRING interaction network

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proteins of unknown 3D structure

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	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (698 aa)
	HCDG_00991	Putative oxidoreductase. (222 aa)
	HCDG_01015	Amine oxidase. (1080 aa)
	HCDG_01063	SHREC complex subunit Mit1. (676 aa)
	HCDG_00022	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (781 aa)
	HCDG_00027	Histone H2A; Belongs to the histone H2A family. (138 aa)
	HCDG_01273	Uncharacterized protein. (196 aa)
	HCDG_01274	RNA-dependent RNA polymerase. (396 aa)
	HCDG_01275	Uncharacterized protein. (155 aa)
	HCDG_00162	C3H1-type domain-containing protein. (718 aa)
	HCDG_00190	SNF2 family helicase/ATPase. (1181 aa)
	HCDG_00440	Set1 complex component ash2. (595 aa)
	HCDG_01983	Mis6 domain-containing protein. (435 aa)
	HCDG_02161	DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1234 aa)
	HCDG_02275	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (377 aa)
	HCDG_02315	Exosome complex exonuclease RRP6. (671 aa)
	HCDG_02316	Uncharacterized protein. (119 aa)
	HCDG_01659	Histone chaperone Rttp106-like protein. (476 aa)
	HCDG_02724	Transcription elongation factor spt6. (113 aa)
	HCDG_02725	Transcription elongation factor spt6. (730 aa)
	HCDG_02726	SPT6_acidic domain-containing protein. (127 aa)
	HCDG_02793	Sir2 family histone deacetylase Hst4. (574 aa)
	HCDG_03043	FACT complex subunit pob3. (152 aa)
	HCDG_03044	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (332 aa)
	HCDG_03242	Serine/threonine protein phosphatase PP1. (154 aa)
	HCDG_03317	Tetratricopeptide repeat domain-containing protein. (466 aa)
	HCDG_03559	CAF1 family ribonuclease. (535 aa)
	HCDG_03654	Uncharacterized protein. (2005 aa)
	HCDG_03720	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	HCDG_04074	Heterochromatin protein HP1. (246 aa)
	HCDG_04333	WD40 domain-containing protein. (568 aa)
	HCDG_04361	Stc1 domain-containing protein. (298 aa)
	HCDG_04476	DNA helicase; Belongs to the MCM family. (857 aa)
	HCDG_04832	Uncharacterized protein. (591 aa)
	HCDG_04938	DEAD box helicase. (975 aa)
	HCDG_04996	zf-C3H1 domain-containing protein. (1308 aa)
	HCDG_04543	C2H2 finger domain-containing protein. (1475 aa)
	HCDG_04683	DNA helicase; Belongs to the MCM family. (718 aa)
	HCDG_04721	BSD domain-containing protein; Belongs to the nucleosome assembly protein (NAP) family. (399 aa)
	HCDG_05405	RING finger domain-containing protein. (125 aa)
	HCDG_05432	Nucleosome assembly protein; Belongs to the nucleosome assembly protein (NAP) family. (351 aa)
	HCDG_05045	Chromo domain-containing protein. (524 aa)
	HCDG_05161	tRNA isopentenyltransferase. (449 aa)
	HCDG_05536	Chromatin assembly factor 1 subunit p60. (758 aa)
	HCDG_05767	RNA-dependent RNA polymerase. (1240 aa)
	HCDG_05862	Uncharacterized protein. (726 aa)
	HCDG_05983	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1092 aa)
	HCDG_06090	Chromatin regulatory protein sir2. (515 aa)
	HCDG_06324	Silent information regulator 2. (424 aa)
	HCDG_06408	Peptidylprolyl isomerase. (492 aa)
	HCDG_06433	PAPA-1 domain-containing protein. (406 aa)
	HCDG_06565	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	HCDG_06587	Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (557 aa)
	HCDG_06771	GATA transcription factor. (901 aa)
	HCDG_06774	Nuclear pore complex subunit Nup192; Belongs to the cullin family. (2454 aa)
	HCDG_06843	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (530 aa)
	HCDG_06912	Uncharacterized protein. (351 aa)
	HCDG_07141	Uncharacterized protein. (489 aa)
	HCDG_07246	CBFD_NFYB_HMF domain-containing protein. (199 aa)
	HCDG_07877	WD40 domain-containing protein. (260 aa)
	HCDG_08001	Uncharacterized protein. (54 aa)
	HCDG_08208	SNF2 family helicase/ATPase. (1762 aa)
	HCDG_08330	RXT2_N domain-containing protein. (555 aa)
	HCDG_08368	Shugoshin. (716 aa)
	HCDG_08902	H15 domain-containing protein. (199 aa)
	HCDG_08788	YEATS family protein. (252 aa)
	HCDG_08481	Arsenite resistance protein Ars2. (915 aa)
	HCDG_08524	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (282 aa)
	HCDG_08540	PHD transcription factor. (900 aa)
	HCDG_08643	PHD finger containing protein Phf1. (565 aa)
	HCDG_09189	Uncharacterized protein. (539 aa)

Your Current Organism:

Histoplasma capsulatum H143

NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCDG_00022	HCDG_00027	C6H3C8	C6H3D3	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone H2A; Belongs to the histone H2A family.	0.794
HCDG_00022	HCDG_00991	C6H3C8	C6H2Q9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Putative oxidoreductase.	0.776
HCDG_00022	HCDG_01015	C6H3C8	C6H2T3	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Amine oxidase.	0.768
HCDG_00022	HCDG_01063	C6H3C8	C6H2Y1	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	SHREC complex subunit Mit1.	0.773
HCDG_00022	HCDG_02161	C6H3C8	C6H6W0	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.489
HCDG_00022	HCDG_02275	C6H3C8	C6H774	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.744
HCDG_00022	HCDG_02793	C6H3C8	C6H9B2	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Sir2 family histone deacetylase Hst4.	0.501
HCDG_00022	HCDG_03720	C6H3C8	C6HCH0	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.887
HCDG_00022	HCDG_04074	C6H3C8	C6HCZ3	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Heterochromatin protein HP1.	0.675
HCDG_00022	HCDG_04543	C6H3C8	C6HF20	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	C2H2 finger domain-containing protein.	0.704
HCDG_00022	HCDG_05045	C6H3C8	C6HGF4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Chromo domain-containing protein.	0.554
HCDG_00022	HCDG_05983	C6H3C8	C6HIU9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.744
HCDG_00022	HCDG_06090	C6H3C8	C6HJ56	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Chromatin regulatory protein sir2.	0.693
HCDG_00022	HCDG_06324	C6H3C8	C6HJE3	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Silent information regulator 2.	0.559
HCDG_00022	HCDG_06565	C6H3C8	C6HK34	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.732
HCDG_00022	HCDG_06912	C6H3C8	C6HL31	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Uncharacterized protein.	0.612
HCDG_00022	HCDG_08001	C6H3C8	C6HP70	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Uncharacterized protein.	0.936
HCDG_00022	HCDG_08208	C6H3C8	C6HPS7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	SNF2 family helicase/ATPase.	0.577
HCDG_00022	HCDG_08524	C6H3C8	C6HRD9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	0.426
HCDG_00022	HCDG_08902	C6H3C8	C6HQI4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	H15 domain-containing protein.	0.426