STRINGSTRING
HCDG_07428 HCDG_07428 HCDG_01961 HCDG_01961 HCDG_02051 HCDG_02051 HCDG_03249 HCDG_03249 HCDG_02191 HCDG_02191 HCDG_06409 HCDG_06409 HCDG_04530 HCDG_04530 HCDG_01177 HCDG_01177 HCDG_00406 HCDG_00406 HCDG_03248 HCDG_03248 HCDG_07091 HCDG_07091 HCDG_09244 HCDG_09244 HCDG_08015 HCDG_08015
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_07428Single-stranded DNA binding protein p30 subunit. (265 aa)
HCDG_01961Checkpoint protein; Belongs to the HUS1 family. (364 aa)
HCDG_02051Serine/threonine protein kinase. (390 aa)
HCDG_03249Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (548 aa)
HCDG_02191DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (630 aa)
HCDG_06409DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1111 aa)
HCDG_04530Meiotic recombination protein; Belongs to the MRE11/RAD32 family. (503 aa)
HCDG_01177RECA_2 domain-containing protein. (423 aa)
HCDG_00406XPG_I_2 domain-containing protein. (756 aa)
HCDG_03248Vezatin domain-containing protein. (314 aa)
HCDG_07091WD40 domain-containing protein. (597 aa)
HCDG_09244Uncharacterized protein. (188 aa)
HCDG_08015DNA repair protein RAD18. (1148 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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