STRINGSTRING
HCDG_07462 HCDG_07462 HCDG_08024 HCDG_08024 HCDG_08065 HCDG_08065 HCDG_08381 HCDG_08381 HCDG_08729 HCDG_08729 HCDG_00550 HCDG_00550 HCDG_01220 HCDG_01220 HCDG_00325 HCDG_00325 HCDG_01725 HCDG_01725 HCDG_01727 HCDG_01727 HCDG_03043 HCDG_03043 HCDG_03044 HCDG_03044 HCDG_03183 HCDG_03183 HCDG_03248 HCDG_03248 HCDG_03249 HCDG_03249 MCM7 MCM7 HCDG_03519 HCDG_03519 HCDG_04476 HCDG_04476 HCDG_04683 HCDG_04683 HCDG_05536 HCDG_05536 HCDG_06236 HCDG_06236 HCDG_05913 HCDG_05913 HCDG_06041 HCDG_06041 HCDG_06340 HCDG_06340 HCDG_06743 HCDG_06743 HCDG_07227 HCDG_07227 HCDG_07428 HCDG_07428 HCDG_07461 HCDG_07461 HCDG_07798 HCDG_07798
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_07462DNA replication licensing factor mcm2. (252 aa)
HCDG_08024DNA primase; Belongs to the eukaryotic-type primase small subunit family. (567 aa)
HCDG_08065MRC1 domain-containing protein. (1491 aa)
HCDG_08381Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (541 aa)
HCDG_08729Chromosome segregation protein. (849 aa)
HCDG_00550Cell division cycle protein. (803 aa)
HCDG_01220Insulin II gene enhancer-binding protein rip1. (734 aa)
HCDG_00325DNA polymerase delta small subunit. (565 aa)
HCDG_01725Uncharacterized protein. (451 aa)
HCDG_01727DNA polymerase delta subunit 4. (214 aa)
HCDG_03043FACT complex subunit pob3. (152 aa)
HCDG_03044FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (332 aa)
HCDG_03183DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (504 aa)
HCDG_03248Vezatin domain-containing protein. (314 aa)
HCDG_03249Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (548 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (698 aa)
HCDG_03519DNA polymerase. (1053 aa)
HCDG_04476DNA helicase; Belongs to the MCM family. (857 aa)
HCDG_04683DNA helicase; Belongs to the MCM family. (718 aa)
HCDG_05536Chromatin assembly factor 1 subunit p60. (758 aa)
HCDG_06236DNA polymerase. (1458 aa)
HCDG_05913PSF1 domain-containing protein. (277 aa)
HCDG_06041DNA replication complex GINS protein psf3. (159 aa)
HCDG_06340DNA helicase; Belongs to the MCM family. (1758 aa)
HCDG_06743DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (633 aa)
HCDG_07227DNA helicase; Belongs to the MCM family. (965 aa)
HCDG_07428Single-stranded DNA binding protein p30 subunit. (265 aa)
HCDG_07461DNA replication licensing factor mcm2; Belongs to the MCM family. (542 aa)
HCDG_07798DNA replication initiation factor Cdc45. (846 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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