144 items (Histoplasma capsulatum H143) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCDG_00183	SRF-type transcription factor RlmA. (636 aa)
	HCDG_00145	Multiprotein-bridging factor 1. (157 aa)
	HCDG_01283	MYB DNA-binding domain-containing protein. (656 aa)
	HCDG_09528	Uncharacterized protein. (147 aa)
	HCDG_09404	SAGA-associated factor 29. (480 aa)
	HCDG_09395	Uncharacterized protein. (399 aa)
	HCDG_09394	Uncharacterized protein. (236 aa)
	HCDG_09189	Uncharacterized protein. (539 aa)
	HCDG_08981	MADS box transcription factor Mcm1. (238 aa)
	HCDG_08976	SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...] (379 aa)
	HCDG_08655	26S protease regulatory subunit 6A-B; Belongs to the AAA ATPase family. (464 aa)
	HCDG_08625	26S protease regulatory subunit 6B. (202 aa)
	HCDG_08622	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (422 aa)
	HCDG_08764	C-type cyclin. (395 aa)
	HCDG_00073	LisH domain-containing protein. (254 aa)
	HCDG_00072	Uncharacterized protein. (60 aa)
	HCDG_00050	Uncharacterized protein. (377 aa)
	HCDG_00027	Histone H2A; Belongs to the histone H2A family. (138 aa)
	HCDG_00022	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (781 aa)
	HCDG_01179	SAP30_Sin3_bdg domain-containing protein. (226 aa)
	HCDG_01066	Chromatin remodeling complex ATPase chain ISW1. (1051 aa)
	HCDG_01028	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (709 aa)
	HCDG_00918	BZIP domain-containing protein. (239 aa)
	HCDG_00864	Serine/threonine protein kinase. (897 aa)
	HCDG_00814	Retinal dehydrogenase; Belongs to the aldehyde dehydrogenase family. (536 aa)
	HCDG_00693	Uncharacterized protein. (402 aa)
	HCDG_00517	Chromatin remodeling complex subunit; Belongs to the actin family. (754 aa)
	HCDG_08748	RING finger domain-containing protein. (552 aa)
	HCDG_08747	Uncharacterized protein. (133 aa)
	HCDG_08395	SWIRM domain-containing protein. (227 aa)
	HCDG_08312	Uncharacterized protein. (279 aa)
	HCDG_08306	DUF1000 domain-containing protein. (229 aa)
	HCDG_08256	RSC complex subunit. (518 aa)
	HCDG_08255	RSC complex subunit. (625 aa)
	HCDG_08201	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (121 aa)
	HCDG_08064	Plus3 domain-containing protein. (638 aa)
	HCDG_08021	WD40 domain-containing protein. (1027 aa)
	HCDG_07987	C6 transcription factor. (226 aa)
	HCDG_07880	Aldehyde dehydrogenase. (460 aa)
	HCDG_07870	Transcription initiation factor TFIID subunit 9. (248 aa)
	HCDG_07859	Helix-loop-helix DNA-binding domain-containing protein. (105 aa)
	HCDG_07802	DUF1014 domain-containing protein. (205 aa)
	HCDG_07720	Uncharacterized protein. (836 aa)
	HCDG_07477	APSES transcription factor. (668 aa)
	HCDG_07414	Uncharacterized protein. (312 aa)
	HCDG_07349	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (131 aa)
	HCDG_07200	C6 zinc finger protein. (663 aa)
	HCDG_07574	Histone-lysine N-methyltransferase. (792 aa)
	HCDG_07033	C6 transcription factor. (731 aa)
	HCDG_06663	APSES transcription factor. (854 aa)
	HCDG_06580	CID domain-containing protein. (246 aa)
	HCDG_06521	RSC complex subunit. (617 aa)
	HCDG_06487	HLH transcription factor. (501 aa)
	HCDG_06486	Uncharacterized protein. (255 aa)
	HCDG_06451	Uncharacterized protein. (628 aa)
	HCDG_05886	Alpha/beta hydrolase fold protein. (333 aa)
	HCDG_05903	Cell differentiation protein rcd1. (423 aa)
	HCDG_05912	HMG box protein. (487 aa)
	HCDG_05978	Uncharacterized protein. (209 aa)
	HCDG_05983	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1092 aa)
	HCDG_06009	Uncharacterized protein. (279 aa)
	HCDG_06106	BHLH domain-containing protein. (539 aa)
	HCDG_06299	Transcriptional co-activator. (420 aa)
	HCDG_06358	ATP-dependent RNA helicase Prh1. (959 aa)
	HCDG_06433	PAPA-1 domain-containing protein. (406 aa)
	HCDG_06438	PtaB protein. (713 aa)
	HCDG_05549	Histone deacetylase HosB. (1022 aa)
	HCDG_05609	PAS domain-containing protein. (399 aa)
	HCDG_05691	Transcriptional regulator PacG/VIB-1. (585 aa)
	HCDG_05735	NDT80 domain-containing protein. (631 aa)
	HCDG_06248	Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (485 aa)
	HCDG_05823	C6 transcription factor. (752 aa)
	HCDG_05861	Prefoldin subunit 5. (186 aa)
	HCDG_05879	Uncharacterized protein. (1296 aa)
	HCDG_05514	RPEL repeat protein. (139 aa)
	HCDG_05480	Uncharacterized protein. (230 aa)
	HCDG_05162	HLA class III protein Dom3z. (344 aa)
	HCDG_05148	Transcriptional repressor TUP1. (587 aa)
	HCDG_05146	Asparagine-rich zinc-finger protein. (454 aa)
	HCDG_05128	CCAAT-binding factor complex subunit HapE. (265 aa)
	HCDG_05436	Serine/threonine protein kinase bur-1. (554 aa)
	HCDG_05427	Forkhead box protein L2. (793 aa)
	HCDG_05411	GTPase inhibitor. (138 aa)
	HCDG_05363	C6 transcription factor. (449 aa)
	HCDG_05354	YTA7 protein. (1689 aa)
	HCDG_05329	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (113 aa)
	HCDG_04635	C6 transcription factor. (701 aa)
	HCDG_04529	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (633 aa)
	HCDG_04964	Uncharacterized protein. (557 aa)
	HCDG_04939	Transcription factor SPT8. (626 aa)
	HCDG_04883	DNA damage repair protein. (639 aa)
	HCDG_04882	BRCT domain-containing protein. (533 aa)
	HCDG_04825	Transcription initiation factor TFIID complex 60 kDa subunit. (470 aa)
	HCDG_04821	Transcription factor TFIID complex subunit Taf11. (247 aa)
	HCDG_04430	GATA transcription factor. (543 aa)
	HCDG_04367	Universal stress protein family domain-containing protein. (755 aa)
	HCDG_04043	CP2 transcription factor. (388 aa)
	HCDG_04036	Uncharacterized protein. (500 aa)
	HCDG_03614	Forkhead box protein C2. (735 aa)
	HCDG_03613	pH-response transcription factor pacC/RIM101. (69 aa)
	HCDG_03612	pH-response transcription factor pacC/RIM101. (416 aa)
	HCDG_03593	CP2 transcription factor. (659 aa)
	HCDG_03586	C2H2 transcription factor. (708 aa)
	HCDG_03991	Uncharacterized protein. (339 aa)
	HCDG_03986	JmjC domain-containing protein. (596 aa)
	HCDG_03875	C6 transcription factor. (833 aa)
	HCDG_03835	Ankyrin repeat protein. (1419 aa)
	HCDG_03289	Transcriptional regulator Ngg1. (584 aa)
	HCDG_03255	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (368 aa)
	HCDG_03250	Uncharacterized protein. (595 aa)
	HCDG_03178	UDP-N-acetylglucosaminyltransferase. (1696 aa)
	HCDG_03174	MYB family conidiophore development protein FlbD. (389 aa)
	HCDG_03088	BHLH domain-containing protein. (195 aa)
	HCDG_03044	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (332 aa)
	HCDG_03043	FACT complex subunit pob3. (152 aa)
	HCDG_03019	Transcription factor HAP3. (215 aa)
	HCDG_02987	Uncharacterized protein. (323 aa)
	HCDG_02966	Uncharacterized protein. (100 aa)
	HCDG_02854	C6 transcription factor. (1008 aa)
	HCDG_02831	Beta-lactamase. (399 aa)
	HCDG_02801	Uncharacterized protein. (266 aa)
	HCDG_02800	Uncharacterized protein. (249 aa)
	MED16	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (944 aa)
	HCDG_02784	Homeobox transcription factor. (732 aa)
	HCDG_02762	M protein repeat protein. (862 aa)
	HCDG_02726	SPT6_acidic domain-containing protein. (127 aa)
	HCDG_02725	Transcription elongation factor spt6. (730 aa)
	HCDG_02724	Transcription elongation factor spt6. (113 aa)
	HCDG_02623	Proteasome regulatory particle subunit Rpt4. (371 aa)
	HCDG_02509	Uncharacterized protein. (211 aa)
	HCDG_02480	Cell division control protein. (534 aa)
	HCDG_01474	RNA polymerase II transcriptional coactivator. (156 aa)
	HCDG_02388	Zinc-responsiveness transcriptional activator. (414 aa)
	HCDG_01863	C6 finger domain-containing protein. (740 aa)
	HCDG_01853	C6 finger domain-containing protein. (361 aa)
	HCDG_01806	Uncharacterized protein. (130 aa)
	HCDG_01689	C2H2 zinc finger protein. (832 aa)
	HCDG_00461	CBF/NF-Y family transcription factor. (153 aa)
	HCDG_00436	Uncharacterized protein. (92 aa)
	HCDG_00435	Uncharacterized protein. (107 aa)
	HCDG_00421	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (720 aa)
	HCDG_00369	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (389 aa)
	HCDG_00242	Nitrogen regulatory protein OTam. (791 aa)
	HCDG_01367	SAGA complex component. (370 aa)

Your Current Organism:

Histoplasma capsulatum H143

NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HCDG_00022	HCDG_00027	C6H3C8	C6H3D3	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone H2A; Belongs to the histone H2A family.	0.794
HCDG_00022	HCDG_00183	C6H3C8	C6H4A2	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	SRF-type transcription factor RlmA.	0.672
HCDG_00022	HCDG_00435	C6H3C8	C6H5B4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Uncharacterized protein.	0.652
HCDG_00022	HCDG_00436	C6H3C8	C6H5B5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Uncharacterized protein.	0.652
HCDG_00022	HCDG_00918	C6H3C8	C6H2I6	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	BZIP domain-containing protein.	0.683
HCDG_00022	HCDG_01066	C6H3C8	C6H2Y4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Chromatin remodeling complex ATPase chain ISW1.	0.611
HCDG_00022	HCDG_01179	C6H3C8	C6H397	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	SAP30_Sin3_bdg domain-containing protein.	0.430
HCDG_00022	HCDG_01689	C6H3C8	C6H5I8	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	C2H2 zinc finger protein.	0.439
HCDG_00022	HCDG_02388	C6H3C8	C6H7I7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Zinc-responsiveness transcriptional activator.	0.439
HCDG_00022	HCDG_02480	C6H3C8	C6H8E9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Cell division control protein.	0.638
HCDG_00022	HCDG_03250	C6H3C8	C6HAL9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Uncharacterized protein.	0.577
HCDG_00022	HCDG_03586	C6H3C8	C6HC37	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	C2H2 transcription factor.	0.439
HCDG_00022	HCDG_03612	C6H3C8	C6HC63	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	pH-response transcription factor pacC/RIM101.	0.439
HCDG_00022	HCDG_03613	C6H3C8	C6HC64	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	pH-response transcription factor pacC/RIM101.	0.439
HCDG_00022	HCDG_04430	C6H3C8	C6HDZ9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	GATA transcription factor.	0.913
HCDG_00022	HCDG_05146	C6H3C8	C6HGQ5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Asparagine-rich zinc-finger protein.	0.439
HCDG_00022	HCDG_05148	C6H3C8	C6HGQ7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Transcriptional repressor TUP1.	0.459
HCDG_00022	HCDG_05363	C6H3C8	C6HG23	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	C6 transcription factor.	0.577
HCDG_00022	HCDG_05691	C6H3C8	C6HHL0	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Transcriptional regulator PacG/VIB-1.	0.439
HCDG_00022	HCDG_05879	C6H3C8	C6HIJ5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Uncharacterized protein.	0.585