46 items (Histoplasma capsulatum H143) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HCDG_02969	Forkhead domain-containing protein. (355 aa)
	HCDG_00662	Phosphoprotein phosphatase A. (617 aa)
	HCDG_00880	WD40 domain-containing protein. (393 aa)
	HCDG_00951	Polyubiquitin. (305 aa)
	HCDG_01063	SHREC complex subunit Mit1. (676 aa)
	HCDG_00005	Uncharacterized protein. (217 aa)
	HCDG_09510	MIT domain-containing protein. (994 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (618 aa)
	HCDG_08900	Phosphatidylinositol-4-phosphate 5-kinase its3. (956 aa)
	GUF1	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (657 aa)
	HCDG_07524	Mitogen-activated protein kinase MAF1. (455 aa)
	HCDG_06645	Uncharacterized protein. (839 aa)
	HCDG_06568	Stress-activated map kinase-interacting protein. (883 aa)
	HCDG_06256	U-box domain-containing protein. (284 aa)
	HCDG_06249	Serine/threonine protein kinase gad8. (68 aa)
	HCDG_06220	Serine/threonine protein kinase. (312 aa)
	HCDG_00343	Leucine rich repeat domain-containing protein. (970 aa)
	HCDG_06144	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (272 aa)
	HCDG_05655	TorA protein; Belongs to the PI3/PI4-kinase family. (2377 aa)
	HCDG_05627	Cytosolic regulator Pianissimo. (1273 aa)
	HCDG_05210	MORN domain-containing protein. (222 aa)
	HCDG_05209	WD_REPEATS_REGION domain-containing protein. (80 aa)
	HCDG_05208	WD40 domain-containing protein. (535 aa)
	HCDG_05369	Uncharacterized protein. (119 aa)
	HCDG_04692	Uncharacterized protein. (213 aa)
	HCDG_04691	Serine/threonine protein phosphatase. (425 aa)
	HCDG_05005	Serine/threonine protein phosphatase. (414 aa)
	HCDG_04913	Uncharacterized protein. (175 aa)
	HCDG_04380	Uncharacterized protein. (141 aa)
	HCDG_04378	E3 ubiquitin protein ligase. (182 aa)
	HCDG_04236	Protein kinase domain-containing protein. (200 aa)
	HCDG_04116	Uncharacterized protein. (179 aa)
	HCDG_04026	Uncharacterized protein. (362 aa)
	HCDG_03736	Uncharacterized protein. (358 aa)
	HCDG_03585	Ubiquitin/79aa fusion protein. (152 aa)
	HCDG_03378	Uncharacterized protein. (132 aa)
	HCDG_03982	Uncharacterized protein. (102 aa)
	HCDG_03981	Uncharacterized protein. (498 aa)
	HCDG_02684	Spindle poison sensitivity protein Scp3. (600 aa)
	HCDG_01505	Fungal specific transcription factor. (760 aa)
	HCDG_01500	BZIP domain-containing protein. (252 aa)
	HCDG_01995	Tuberin. (223 aa)
	HCDG_01994	Tuberin. (1212 aa)
	HCDG_01816	Uncharacterized protein. (158 aa)
	HCDG_01796	Uncharacterized protein. (180 aa)
	HCDG_01754	Serine/threonine-protein phosphatase. (316 aa)

Your Current Organism:

Histoplasma capsulatum H143

NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GUF1	HCDG_00951	C6HPI9	C6H2L9	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Polyubiquitin.	0.667
GUF1	HCDG_01500	C6HPI9	C6H7T9	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	BZIP domain-containing protein.	0.686
GUF1	HCDG_03585	C6HPI9	C6HC36	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.	Ubiquitin/79aa fusion protein.	0.686
HCDG_00005	HCDG_01505	C6H3B1	C6H7U4	Uncharacterized protein.	Fungal specific transcription factor.	0.609
HCDG_00005	HCDG_06144	C6H3B1	C6HHZ4	Uncharacterized protein.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.609
HCDG_00005	HCDG_06220	C6H3B1	C6HI70	Uncharacterized protein.	Serine/threonine protein kinase.	0.603
HCDG_00005	MDM34	C6H3B1	C6HQX6	Uncharacterized protein.	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	0.603
HCDG_00343	HCDG_00662	C6H522	C6H1T0	Leucine rich repeat domain-containing protein.	Phosphoprotein phosphatase A.	0.438
HCDG_00343	HCDG_00951	C6H522	C6H2L9	Leucine rich repeat domain-containing protein.	Polyubiquitin.	0.478
HCDG_00343	HCDG_01500	C6H522	C6H7T9	Leucine rich repeat domain-containing protein.	BZIP domain-containing protein.	0.478
HCDG_00343	HCDG_01754	C6H522	C6H5Q3	Leucine rich repeat domain-containing protein.	Serine/threonine-protein phosphatase.	0.641
HCDG_00343	HCDG_03585	C6H522	C6HC36	Leucine rich repeat domain-containing protein.	Ubiquitin/79aa fusion protein.	0.478
HCDG_00343	HCDG_05005	C6H522	C6HEY8	Leucine rich repeat domain-containing protein.	Serine/threonine protein phosphatase.	0.641
HCDG_00662	HCDG_00343	C6H1T0	C6H522	Phosphoprotein phosphatase A.	Leucine rich repeat domain-containing protein.	0.438
HCDG_00662	HCDG_00951	C6H1T0	C6H2L9	Phosphoprotein phosphatase A.	Polyubiquitin.	0.691
HCDG_00662	HCDG_01500	C6H1T0	C6H7T9	Phosphoprotein phosphatase A.	BZIP domain-containing protein.	0.648
HCDG_00662	HCDG_01754	C6H1T0	C6H5Q3	Phosphoprotein phosphatase A.	Serine/threonine-protein phosphatase.	0.999
HCDG_00662	HCDG_02969	C6H1T0	C6H9T8	Phosphoprotein phosphatase A.	Forkhead domain-containing protein.	0.528
HCDG_00662	HCDG_03585	C6H1T0	C6HC36	Phosphoprotein phosphatase A.	Ubiquitin/79aa fusion protein.	0.648
HCDG_00662	HCDG_04691	C6H1T0	C6HFG8	Phosphoprotein phosphatase A.	Serine/threonine protein phosphatase.	0.987