STRINGSTRING
HCDG_08381 HCDG_08381 HCDG_08497 HCDG_08497 HCDG_00642 HCDG_00642 HCDG_00951 HCDG_00951 HCDG_01177 HCDG_01177 HCDG_01727 HCDG_01727 HCDG_02051 HCDG_02051 HCDG_02191 HCDG_02191 HCDG_01500 HCDG_01500 HCDG_08112 HCDG_08112 HCDG_07288 HCDG_07288 HCDG_01632 HCDG_01632 HCDG_00573 HCDG_00573 HCDG_02809 HCDG_02809 HCDG_03831 HCDG_03831 HCDG_03938 HCDG_03938 HCDG_04600 HCDG_04600 SLX1 SLX1 HCDG_03657 HCDG_03657 HCDG_03585 HCDG_03585 HCDG_03377 HCDG_03377 HCDG_06884 HCDG_06884 HCDG_06388 HCDG_06388
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_08381Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (541 aa)
HCDG_08497Uncharacterized protein. (387 aa)
HCDG_00642Uncharacterized protein. (369 aa)
HCDG_00951Polyubiquitin. (305 aa)
HCDG_01177RECA_2 domain-containing protein. (423 aa)
HCDG_01727DNA polymerase delta subunit 4. (214 aa)
HCDG_02051Serine/threonine protein kinase. (390 aa)
HCDG_02191DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (630 aa)
HCDG_01500BZIP domain-containing protein. (252 aa)
HCDG_08112Rad51 family DNA repair protein. (455 aa)
HCDG_07288Asparaginyl-tRNA synthetase. (508 aa)
HCDG_01632ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (572 aa)
HCDG_00573PCRan1 kinase; Belongs to the protein kinase superfamily. (401 aa)
HCDG_02809DNA repair protein RAD51. (249 aa)
HCDG_03831RecA family ATPase Rhp57. (701 aa)
HCDG_03938Uncharacterized protein. (772 aa)
HCDG_04600ERCC4 domain-containing protein. (197 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (421 aa)
HCDG_03657Crossover junction endonuclease mus81. (650 aa)
HCDG_03585Ubiquitin/79aa fusion protein. (152 aa)
HCDG_033773'-5' exonuclease/helicase. (947 aa)
HCDG_06884Protein kinase. (713 aa)
HCDG_06388RecQ family helicase MusN. (1559 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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