STRINGSTRING
HCDG_02486 HCDG_02486 HCDG_07461 HCDG_07461 HCDG_02641 HCDG_02641 HCDG_02679 HCDG_02679 HCDG_02765 HCDG_02765 HCDG_04768 HCDG_04768 HCDG_04616 HCDG_04616 HCDG_04683 HCDG_04683 HCDG_05357 HCDG_05357 HCDG_05443 HCDG_05443 HCDG_05071 HCDG_05071 HCDG_06236 HCDG_06236 HCDG_06047 HCDG_06047 HCDG_06340 HCDG_06340 HCDG_06743 HCDG_06743 HCDG_01030 HCDG_01030 HCDG_00776 HCDG_00776 HCDG_00550 HCDG_00550 HCDG_06770 HCDG_06770 HCDG_06958 HCDG_06958 HCDG_07227 HCDG_07227 HCDG_02792 HCDG_02792 HCDG_02856 HCDG_02856 HCDG_03183 HCDG_03183 HCDG_03318 HCDG_03318 MCM7 MCM7 HCDG_03389 HCDG_03389 HCDG_03665 HCDG_03665 HCDG_04018 HCDG_04018 HCDG_04227 HCDG_04227 HCDG_04362 HCDG_04362 HCDG_07428 HCDG_07428 HCDG_07246 HCDG_07246 HCDG_04476 HCDG_04476 HCDG_07462 HCDG_07462 HCDG_07798 HCDG_07798 HCDG_08024 HCDG_08024 HCDG_08381 HCDG_08381 HCDG_09318 HCDG_09318 HCDG_04365 HCDG_04365 HCDG_02270 HCDG_02270 HCDG_01725 HCDG_01725 HCDG_01565 HCDG_01565
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_02486Origin recognition complex subunit. (755 aa)
HCDG_07461DNA replication licensing factor mcm2; Belongs to the MCM family. (542 aa)
HCDG_02641Uncharacterized protein. (123 aa)
HCDG_02679Serine/threonine protein kinase. (501 aa)
HCDG_02765Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (828 aa)
HCDG_04768Uncharacterized protein. (171 aa)
HCDG_04616Uncharacterized protein. (404 aa)
HCDG_04683DNA helicase; Belongs to the MCM family. (718 aa)
HCDG_05357Origin recognition complex subunit. (686 aa)
HCDG_05443Uncharacterized protein. (108 aa)
HCDG_05071Origin recognition complex subunit Orc5. (485 aa)
HCDG_06236DNA polymerase. (1458 aa)
HCDG_06047Uncharacterized protein. (605 aa)
HCDG_06340DNA helicase; Belongs to the MCM family. (1758 aa)
HCDG_06743DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (633 aa)
HCDG_01030TPR domain-containing protein. (370 aa)
HCDG_00776Uncharacterized protein. (122 aa)
HCDG_00550Cell division cycle protein. (803 aa)
HCDG_06770SsDNA binding protein Ssb3. (117 aa)
HCDG_06958Uncharacterized protein. (84 aa)
HCDG_07227DNA helicase; Belongs to the MCM family. (965 aa)
HCDG_02792Uncharacterized protein. (309 aa)
HCDG_02856Uncharacterized protein. (168 aa)
HCDG_03183DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (504 aa)
HCDG_03318DNA polymerase epsilon subunit B. (644 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (698 aa)
HCDG_03389Cell division control protein; Belongs to the CDC6/cdc18 family. (553 aa)
HCDG_03665Uncharacterized protein. (61 aa)
HCDG_04018Telomere silencing protein Zds1. (843 aa)
HCDG_04227G1/S regulator. (676 aa)
HCDG_04362OB-fold nucleic acid binding domain-containing protein. (280 aa)
HCDG_07428Single-stranded DNA binding protein p30 subunit. (265 aa)
HCDG_07246CBFD_NFYB_HMF domain-containing protein. (199 aa)
HCDG_04476DNA helicase; Belongs to the MCM family. (857 aa)
HCDG_07462DNA replication licensing factor mcm2. (252 aa)
HCDG_07798DNA replication initiation factor Cdc45. (846 aa)
HCDG_08024DNA primase; Belongs to the eukaryotic-type primase small subunit family. (567 aa)
HCDG_08381Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (541 aa)
HCDG_09318Origin recognition complex subunit Orc2. (556 aa)
HCDG_04365DnaJ protein. (331 aa)
HCDG_02270DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2111 aa)
HCDG_01725Uncharacterized protein. (451 aa)
HCDG_01565Uncharacterized protein. (314 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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