STRINGSTRING
HCDG_02856 HCDG_02856 FEN1 FEN1 HCDG_08381 HCDG_08381 HCDG_08024 HCDG_08024 HCDG_06958 HCDG_06958 HCDG_06770 HCDG_06770 HCDG_06743 HCDG_06743 HCDG_06104 HCDG_06104 HCDG_06047 HCDG_06047 HCDG_06236 HCDG_06236 HCDG_05443 HCDG_05443 HCDG_04616 HCDG_04616 HCDG_04768 HCDG_04768 HCDG_04018 HCDG_04018 HCDG_03665 HCDG_03665 HCDG_03605 HCDG_03605 HCDG_03519 HCDG_03519 HCDG_03249 HCDG_03249 HCDG_03248 HCDG_03248 HCDG_03183 HCDG_03183 HCDG_02641 HCDG_02641 HCDG_01565 HCDG_01565 HCDG_01727 HCDG_01727 HCDG_00325 HCDG_00325 HCDG_01369 HCDG_01369 HCDG_01030 HCDG_01030 HCDG_00776 HCDG_00776
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_02856Uncharacterized protein. (168 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
HCDG_08381Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (541 aa)
HCDG_08024DNA primase; Belongs to the eukaryotic-type primase small subunit family. (567 aa)
HCDG_06958Uncharacterized protein. (84 aa)
HCDG_06770SsDNA binding protein Ssb3. (117 aa)
HCDG_06743DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (633 aa)
HCDG_06104DNA replication ATP-dependent helicase dna2. (1609 aa)
HCDG_06047Uncharacterized protein. (605 aa)
HCDG_06236DNA polymerase. (1458 aa)
HCDG_05443Uncharacterized protein. (108 aa)
HCDG_04616Uncharacterized protein. (404 aa)
HCDG_04768Uncharacterized protein. (171 aa)
HCDG_04018Telomere silencing protein Zds1. (843 aa)
HCDG_03665Uncharacterized protein. (61 aa)
HCDG_03605DNA ligase. (844 aa)
HCDG_03519DNA polymerase. (1053 aa)
HCDG_03249Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (548 aa)
HCDG_03248Vezatin domain-containing protein. (314 aa)
HCDG_03183DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (504 aa)
HCDG_02641Uncharacterized protein. (123 aa)
HCDG_01565Uncharacterized protein. (314 aa)
HCDG_01727DNA polymerase delta subunit 4. (214 aa)
HCDG_00325DNA polymerase delta small subunit. (565 aa)
HCDG_01369DNA ligase. (899 aa)
HCDG_01030TPR domain-containing protein. (370 aa)
HCDG_00776Uncharacterized protein. (122 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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