STRINGSTRING
HCDG_00537 HCDG_00537 HCDG_00550 HCDG_00550 HCDG_00573 HCDG_00573 HCDG_00642 HCDG_00642 HCDG_00776 HCDG_00776 HCDG_00951 HCDG_00951 HCDG_00968 HCDG_00968 HCDG_00969 HCDG_00969 HCDG_01030 HCDG_01030 HCDG_00014 HCDG_00014 HCDG_00042 HCDG_00042 HCDG_01409 HCDG_01409 HCDG_00199 HCDG_00199 HCDG_00277 HCDG_00277 HCDG_00385 HCDG_00385 HCDG_00386 HCDG_00386 HCDG_01725 HCDG_01725 HCDG_01735 HCDG_01735 HCDG_01961 HCDG_01961 HCDG_02051 HCDG_02051 HCDG_02070 HCDG_02070 HCDG_02191 HCDG_02191 HCDG_02221 HCDG_02221 HCDG_01500 HCDG_01500 HCDG_01565 HCDG_01565 HCDG_01632 HCDG_01632 HCDG_02486 HCDG_02486 HCDG_02628 HCDG_02628 HCDG_02641 HCDG_02641 HCDG_02679 HCDG_02679 HCDG_02765 HCDG_02765 HCDG_02856 HCDG_02856 HCDG_02937 HCDG_02937 HCDG_02957 HCDG_02957 HCDG_03857 HCDG_03857 MCM7 MCM7 HCDG_03377 HCDG_03377 HCDG_03389 HCDG_03389 HCDG_03405 HCDG_03405 HCDG_03585 HCDG_03585 HCDG_03621 HCDG_03621 HCDG_03665 HCDG_03665 HCDG_03703 HCDG_03703 HCDG_03767 HCDG_03767 HCDG_03782 HCDG_03782 HCDG_04018 HCDG_04018 HCDG_04227 HCDG_04227 HCDG_04301 HCDG_04301 HCDG_04302 HCDG_04302 HCDG_04309 HCDG_04309 HCDG_04476 HCDG_04476 HCDG_04768 HCDG_04768 HCDG_05005 HCDG_05005 HCDG_04616 HCDG_04616 HCDG_04683 HCDG_04683 HCDG_05235 HCDG_05235 HCDG_05357 HCDG_05357 HCDG_05443 HCDG_05443 HCDG_05071 HCDG_05071 HCDG_05173 HCDG_05173 HCDG_05181 HCDG_05181 HCDG_05547 HCDG_05547 HCDG_06242 HCDG_06242 HCDG_06047 HCDG_06047 HCDG_06340 HCDG_06340 HCDG_06388 HCDG_06388 HCDG_06490 HCDG_06490 HCDG_06708 HCDG_06708 HCDG_06720 HCDG_06720 HCDG_06721 HCDG_06721 HCDG_06762 HCDG_06762 HCDG_06770 HCDG_06770 HCDG_06884 HCDG_06884 HCDG_06958 HCDG_06958 HCDG_06972 HCDG_06972 HCDG_07157 HCDG_07157 HCDG_07227 HCDG_07227 HCDG_07428 HCDG_07428 HCDG_07461 HCDG_07461 HCDG_07462 HCDG_07462 HCDG_07644 HCDG_07644 HCDG_07798 HCDG_07798 HCDG_08001 HCDG_08001 HCDG_08037 HCDG_08037 HCDG_08065 HCDG_08065 HCDG_08121 HCDG_08121 HCDG_08352 HCDG_08352 HCDG_08381 HCDG_08381 HCDG_08699 HCDG_08699 HCDG_08743 HCDG_08743 HCDG_08440 HCDG_08440 HCDG_08497 HCDG_08497 HCDG_08967 HCDG_08967 HCDG_09318 HCDG_09318
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_00537HEC/Ndc80p family protein. (734 aa)
HCDG_00550Cell division cycle protein. (803 aa)
HCDG_00573PCRan1 kinase; Belongs to the protein kinase superfamily. (401 aa)
HCDG_00642Uncharacterized protein. (369 aa)
HCDG_00776Uncharacterized protein. (122 aa)
HCDG_00951Polyubiquitin. (305 aa)
HCDG_00968DNA repair protein RAD1. (401 aa)
HCDG_00969Uncharacterized protein. (77 aa)
HCDG_01030TPR domain-containing protein. (370 aa)
HCDG_00014DNA replication factor C subunit Rfc3. (345 aa)
HCDG_00042Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (1109 aa)
HCDG_01409Nuclear distribution protein NudE. (584 aa)
HCDG_00199DNA replication factor C subunit Rfc2. (394 aa)
HCDG_00277Uncharacterized protein. (836 aa)
HCDG_00385Uncharacterized protein. (711 aa)
HCDG_00386Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1490 aa)
HCDG_01725Uncharacterized protein. (451 aa)
HCDG_01735Spindle assembly checkpoint protein SLDB. (374 aa)
HCDG_01961Checkpoint protein; Belongs to the HUS1 family. (364 aa)
HCDG_02051Serine/threonine protein kinase. (390 aa)
HCDG_02070Spindle pole body component alp14. (926 aa)
HCDG_02191DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (630 aa)
HCDG_02221Cytoplasm to vacuole targeting Vps64. (760 aa)
HCDG_01500BZIP domain-containing protein. (252 aa)
HCDG_01565Uncharacterized protein. (314 aa)
HCDG_01632ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (572 aa)
HCDG_02486Origin recognition complex subunit. (755 aa)
HCDG_026283 protein epsilon; Belongs to the 14-3-3 family. (293 aa)
HCDG_02641Uncharacterized protein. (123 aa)
HCDG_02679Serine/threonine protein kinase. (501 aa)
HCDG_02765Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (828 aa)
HCDG_02856Uncharacterized protein. (168 aa)
HCDG_02937DNA damage checkpoint protein rad24; Belongs to the 14-3-3 family. (268 aa)
HCDG_02957Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (999 aa)
HCDG_03857Cell cycle checkpoint protein rad17. (967 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (698 aa)
HCDG_033773'-5' exonuclease/helicase. (947 aa)
HCDG_03389Cell division control protein; Belongs to the CDC6/cdc18 family. (553 aa)
HCDG_03405Protein kinase. (397 aa)
HCDG_03585Ubiquitin/79aa fusion protein. (152 aa)
HCDG_03621Microtubule-associated protein EB1. (221 aa)
HCDG_03665Uncharacterized protein. (61 aa)
HCDG_03703Spindle assembly checkpoint component mad1. (794 aa)
HCDG_03767Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (543 aa)
HCDG_03782Uncharacterized protein. (359 aa)
HCDG_04018Telomere silencing protein Zds1. (843 aa)
HCDG_04227G1/S regulator. (676 aa)
HCDG_04301Mitotic spindle checkpoint component mad3. (331 aa)
HCDG_04302Protein kinase domain-containing protein. (597 aa)
HCDG_04309M-phase inducer phosphatase. (437 aa)
HCDG_04476DNA helicase; Belongs to the MCM family. (857 aa)
HCDG_04768Uncharacterized protein. (171 aa)
HCDG_05005Serine/threonine protein phosphatase. (414 aa)
HCDG_04616Uncharacterized protein. (404 aa)
HCDG_04683DNA helicase; Belongs to the MCM family. (718 aa)
HCDG_05235Dynein light intermediate chain. (543 aa)
HCDG_05357Origin recognition complex subunit. (686 aa)
HCDG_05443Uncharacterized protein. (108 aa)
HCDG_05071Origin recognition complex subunit Orc5. (485 aa)
HCDG_05173Activator 1 37 kDa subunit. (354 aa)
HCDG_05181AGC kinase. (590 aa)
HCDG_05547Serine/threonine protein kinase. (631 aa)
HCDG_06242DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (450 aa)
HCDG_06047Uncharacterized protein. (605 aa)
HCDG_06340DNA helicase; Belongs to the MCM family. (1758 aa)
HCDG_06388RecQ family helicase MusN. (1559 aa)
HCDG_06490Activator 1 38 kDa subunit. (325 aa)
HCDG_06708BRCT domain-containing protein. (891 aa)
HCDG_06720Uncharacterized protein. (452 aa)
HCDG_06721Uncharacterized protein. (685 aa)
HCDG_06762Protein kinase; Belongs to the protein kinase superfamily. (482 aa)
HCDG_06770SsDNA binding protein Ssb3. (117 aa)
HCDG_06884Protein kinase. (713 aa)
HCDG_06958Uncharacterized protein. (84 aa)
HCDG_06972Noc1p protein. (655 aa)
HCDG_07157Kinetochore protein. (464 aa)
HCDG_07227DNA helicase; Belongs to the MCM family. (965 aa)
HCDG_07428Single-stranded DNA binding protein p30 subunit. (265 aa)
HCDG_07461DNA replication licensing factor mcm2; Belongs to the MCM family. (542 aa)
HCDG_07462DNA replication licensing factor mcm2. (252 aa)
HCDG_07644Uncharacterized protein. (103 aa)
HCDG_07798DNA replication initiation factor Cdc45. (846 aa)
HCDG_08001Uncharacterized protein. (54 aa)
HCDG_08037ELYS domain-containing protein. (342 aa)
HCDG_08065MRC1 domain-containing protein. (1491 aa)
HCDG_08121Mitotic spindle checkpoint component mad2. (229 aa)
HCDG_08352Kinetochore protein. (287 aa)
HCDG_08381Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (541 aa)
HCDG_08699Cupin domain-containing protein. (618 aa)
HCDG_08743Tousled-like kinase. (489 aa)
HCDG_08440Serine/threonine protein kinase. (1106 aa)
HCDG_08497Uncharacterized protein. (387 aa)
HCDG_08967Pregnancy upregulated non-ubiquitously expressed CaM kinase. (653 aa)
HCDG_09318Origin recognition complex subunit Orc2. (556 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.