STRINGSTRING
HCDG_06706 HCDG_06706 HCDG_06707 HCDG_06707 HCDG_06715 HCDG_06715 HCDG_06775 HCDG_06775 HCDG_06844 HCDG_06844 HCDG_06984 HCDG_06984 HCDG_07022 HCDG_07022 HCDG_07027 HCDG_07027 HCDG_07412 HCDG_07412 HCDG_07989 HCDG_07989 HCDG_08002 HCDG_08002 HCDG_08131 HCDG_08131 HCDG_08177 HCDG_08177 HCDG_08178 HCDG_08178 HCDG_08188 HCDG_08188 HCDG_08307 HCDG_08307 HCDG_08388 HCDG_08388 HCDG_08863 HCDG_08863 HCDG_08714 HCDG_08714 MDM34 MDM34 HCDG_08598 HCDG_08598 HCDG_08935 HCDG_08935 HCDG_09128 HCDG_09128 HCDG_00660 HCDG_00660 HCDG_00951 HCDG_00951 HCDG_01029 HCDG_01029 HCDG_01061 HCDG_01061 HCDG_01098 HCDG_01098 HCDG_02059 HCDG_02059 HCDG_02159 HCDG_02159 HCDG_02340 HCDG_02340 HCDG_02372 HCDG_02372 HCDG_01500 HCDG_01500 HCDG_01503 HCDG_01503 HCDG_01505 HCDG_01505 HCDG_01666 HCDG_01666 HCDG_02712 HCDG_02712 HCDG_02713 HCDG_02713 HCDG_03378 HCDG_03378 HCDG_03531 HCDG_03531 HCDG_03585 HCDG_03585 HCDG_04026 HCDG_04026 HCDG_04116 HCDG_04116 HCDG_04200 HCDG_04200 HCDG_04231 HCDG_04231 HCDG_04767 HCDG_04767 HCDG_05000 HCDG_05000 HCDG_04533 HCDG_04533 HCDG_04548 HCDG_04548 HCDG_05233 HCDG_05233 HCDG_05235 HCDG_05235 HCDG_05362 HCDG_05362 HCDG_05156 HCDG_05156 HCDG_05792 HCDG_05792 HCDG_06144 HCDG_06144 HCDG_06220 HCDG_06220 HCDG_06274 HCDG_06274 HCDG_05955 HCDG_05955 HCDG_06086 HCDG_06086 HCDG_06411 HCDG_06411
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HCDG_06706ESCRT-III component. (216 aa)
HCDG_06707Transmembrane GTPase fzo1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (937 aa)
HCDG_06715Ubiquitin C-terminal hydrolase; Belongs to the peptidase C19 family. (734 aa)
HCDG_06775Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2777 aa)
HCDG_06844ATG16 domain-containing protein. (152 aa)
HCDG_06984Casein kinase subunit II. (161 aa)
HCDG_07022Uncharacterized protein. (196 aa)
HCDG_07027Uncharacterized protein. (550 aa)
HCDG_07412Protein kinase. (1492 aa)
HCDG_07989UV radiation resistance protein. (668 aa)
HCDG_08002Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (454 aa)
HCDG_08131Uncharacterized protein. (631 aa)
HCDG_08177Autophagocytosis protein Aut1. (134 aa)
HCDG_08178Autophagy-related protein 3. (242 aa)
HCDG_08188DUF1649 domain-containing protein. (208 aa)
HCDG_08307SNF7 family protein. (211 aa)
HCDG_08388Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (702 aa)
HCDG_08863Mitochondrial import receptor subunit TOM22. (159 aa)
HCDG_08714Autophagy-related protein. (118 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (618 aa)
HCDG_08598ATG11 domain-containing protein. (1303 aa)
HCDG_08935Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family. (156 aa)
HCDG_09128Autophagy_act_C domain-containing protein. (265 aa)
HCDG_0066040S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (1054 aa)
HCDG_00951Polyubiquitin. (305 aa)
HCDG_01029Uncharacterized protein. (114 aa)
HCDG_01061C-x8-C-x5-C-x3-H type zinc finger protein. (554 aa)
HCDG_01098DUF3543 domain-containing protein. (256 aa)
HCDG_02059Magnesium dependent phosphatase. (222 aa)
HCDG_02159Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (393 aa)
HCDG_02340ESCRT-III component. (209 aa)
HCDG_02372CBS protein. (539 aa)
HCDG_01500BZIP domain-containing protein. (252 aa)
HCDG_01503Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (367 aa)
HCDG_01505Fungal specific transcription factor. (760 aa)
HCDG_01666Uncharacterized protein. (126 aa)
HCDG_02712ZZ type zinc finger domain-containing protein. (449 aa)
HCDG_02713ZZ type zinc finger domain-containing protein. (168 aa)
HCDG_03378Uncharacterized protein. (132 aa)
HCDG_03531SNF7 family protein. (486 aa)
HCDG_03585Ubiquitin/79aa fusion protein. (152 aa)
HCDG_04026Uncharacterized protein. (362 aa)
HCDG_04116Uncharacterized protein. (179 aa)
HCDG_04200Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (827 aa)
HCDG_04231Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (179 aa)
HCDG_04767Uncharacterized protein. (189 aa)
HCDG_05000Phosphatidylinositol 3-kinase VPS34. (836 aa)
HCDG_04533Mitochondrial import receptor subunit TOM20. (175 aa)
HCDG_04548Vacuolar sorting protein. (151 aa)
HCDG_05233SVP1-like protein. (370 aa)
HCDG_05235Dynein light intermediate chain. (543 aa)
HCDG_05362Vacuolar targeting protein Atg18. (330 aa)
HCDG_05156Mitochondrial import receptor subunit TOM40. (352 aa)
HCDG_05792Snf1 kinase complex beta-subunit Gal83. (405 aa)
HCDG_06144Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (272 aa)
HCDG_06220Serine/threonine protein kinase. (312 aa)
HCDG_06274Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (336 aa)
HCDG_05955Cell division control protein. (266 aa)
HCDG_06086Ubiquitin-conjugating enzyme. (135 aa)
HCDG_06411DJ-1/PfpI protein. (227 aa)
Your Current Organism:
Histoplasma capsulatum H143
NCBI taxonomy Id: 544712
Other names: Ajellomyces capsulatus H143, H. capsulatum H143
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